1. Presenter Name: Ijaz ullah
Roll #: 42
Department: Biochemistry
Program : M.Sc
Semester: 1st
Subject : Biochemistry-I
Presentation Topic: Isomerism in lipids,
Storage of lipids
2. ISOMERISM IN LIPIDS
Cis and trans isomerism is found in unsaturated
fats, because of the presence of double bond .
The specific isomerism present in a particular
lipid have significant effects on the lipid s,
structure properties and function in living
organisms.
This geometric isomerism is shown when the
double is present tin the middle on any where
else in the chain except for the terminal
position.
3. Cis isomerism:
The orientation of the substitutes on the same side the
double bond result in the cis bond formation, as
4. GEOMETRY :
Due to presence of same substituent on the
same side ,the two substituent repel each other
which causes a kink in the chain as above .
So the cis isomers are always bent or kinked
preventing cis fstty acids from packing closely
together.
Functional properties:
The isoe packing of the cis isomer helps to
maintain the fluidity as in cellular membranes.
This also gives the lipid a typical liquid state on
room temperature.
5. TRANS ISOMERSM :
If the same substituent lie on the
opposite side of the double bond the
isomer will be trans as
Geometry:
Trans isomer are structurally similar to saturated fatty
acids because the hydrocarbon chain dose not contain
a kink.
Both saturated and Tran fatty acids pack closely
together as monomers when they are present in fats.
Trans isomers do not alter the geometry of the fats.
6. Functional:
Trans fatty acids are present in natural foods.
They also raise blood cholesterol levels
particular of LDL cholesterol.
Trans fatty acids reduce the HDL cholesterol
and can raise the risk of coronary heart
disease.
7. How are lipids stored in the body?
Lipids such as cholesterol, cholesteryl esters and
triglycerides are stored in your body primarily in
specialized fat cells called adipocytes, which comprise
a specialized fatty tissue called adipose tissue.
Stored lipids can be derived from thelipids in your
diet or from lipids that your body synthesizes.
Adipocytes have an almost unlimited capacity to
store lipids in cell organelles called lipid droplets,
which can grow to a very large size.
Although adipose tissue has essential
functions in your body, excessive lipid storage
can compromise cell function.
