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Bart Geerts
MD PhD MSc
Health care & deep learning
My background
▪ Haven’t gone far ….
▪ Married and two boys
▪ Education:
▪ MD, PhD, MSc Biomedical sciences, MBA
▪ Anaesthetist, ICU physician, & clin. pharmacologist
▪ Work:
▪ Previously @ LUMC, Rijnland, UCL, WHO
▪ Cardiac-anaesthetist @ AMC
▪ Academic @ AMC & other places
▪ Advisor @ NLC Health Incubator & Philips
▪ Medical lead @ Scyfer
My mission:
To rid health care of some of its legacy issues
While cost increased ….
%GDP
Let’s develop new things to improve care..
▪ Academic research
▪ PhDs
▪ Scientific communication;
▪ 29,000 journals
▪ > 60,000,000 articles
▪ 5% growth/ year
▪ Everyone on his/her own; impact factors, H-factor,
grants
Research: still an option?
Data use today
▪ Orders, reports and communication
▪ Health care continuity
▪ Legal reseasons
▪ Billing
Time for something new
We want a computer to do something for us. How do we go about?
It is easier when a computer learns through examples, just like a child would do it!
Data
Decision
Learning
or
Algo Error
Why is ML relevant now?
Source: United Nations Economic Commission for Europe (UNECE) Source: Ray Kurzweil (main futurist @ Google), KurzweilAI.net
DATA COMPUTING POWER
My vision
▪ Use data smarter;
▪ Prevent
▪ Diagnose
▪ Personalize
▪ More quality, reduce cost and connect
Bone segmentation in CT scans
Deep Learning prestaties bij analyse van CT scans
Prediction of Alzheimer in MRI
Prediction and diagnosis in retina scans
Input Output:
highlight areas of interest
Damage indication
+ Classification:
35,8% chance stage 0
54,8% chance stage 1
9,40% chance stage 2
< 1% change stage 3
< 1% change stage 4
Predicting waiting times or disease events
Case of perioperative infections
▪ 234,000,000 surgical procedures / year
▪ 40% budget health care
▪ 1 in 4 patients get a complication
▪ Cost up 11.626 USD & HLOS up 114-150%
Weiser Lancet 2008, Eapen JAMA 2013, Dimick AM J Coll Surg 2003, Gawande Surgery 1999
Results: Predictive value
Source: https://en.wikipedia.org/wiki/Precision_and_recall
Digital pathology
Wat is dit?
All data
classificatie
dokter gebruikt
analyse
zoekt naar
onzekere
resultaten
Stelt vragen
Geeft feedback
algoritme
Active learning
“I am afraid the doctor didn’t make it”
ML will change health care
▪ Health and health care
▪ Prevent, diagnose, personalise
▪ Less hospital
▪ Enhance quality, and outcomes
▪ BUT ALWAYS IN COOPERATION
Scyfer B.V.
Science Park 400
1098 XH Amsterdam
bart@scyfer.nl
www.scyfer.nl
I am looking for;
-  Health CHALLENGES
-  DATA
-  Above all: Motivated and skilled PEOPLE

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Bart Geerts - Scyfer - New technologies will change healthcare fundamentally - HealthTech & The City - AmsterdamTechCity - 21 JUNE 2018

  • 1. Bart Geerts MD PhD MSc Health care & deep learning
  • 2. My background ▪ Haven’t gone far …. ▪ Married and two boys ▪ Education: ▪ MD, PhD, MSc Biomedical sciences, MBA ▪ Anaesthetist, ICU physician, & clin. pharmacologist ▪ Work: ▪ Previously @ LUMC, Rijnland, UCL, WHO ▪ Cardiac-anaesthetist @ AMC ▪ Academic @ AMC & other places ▪ Advisor @ NLC Health Incubator & Philips ▪ Medical lead @ Scyfer
  • 3. My mission: To rid health care of some of its legacy issues
  • 5. Let’s develop new things to improve care.. ▪ Academic research ▪ PhDs ▪ Scientific communication; ▪ 29,000 journals ▪ > 60,000,000 articles ▪ 5% growth/ year ▪ Everyone on his/her own; impact factors, H-factor, grants
  • 7. Data use today ▪ Orders, reports and communication ▪ Health care continuity ▪ Legal reseasons ▪ Billing
  • 8. Time for something new We want a computer to do something for us. How do we go about? It is easier when a computer learns through examples, just like a child would do it! Data Decision Learning or Algo Error
  • 9. Why is ML relevant now? Source: United Nations Economic Commission for Europe (UNECE) Source: Ray Kurzweil (main futurist @ Google), KurzweilAI.net DATA COMPUTING POWER
  • 10. My vision ▪ Use data smarter; ▪ Prevent ▪ Diagnose ▪ Personalize ▪ More quality, reduce cost and connect
  • 11. Bone segmentation in CT scans Deep Learning prestaties bij analyse van CT scans
  • 13. Prediction and diagnosis in retina scans Input Output: highlight areas of interest Damage indication + Classification: 35,8% chance stage 0 54,8% chance stage 1 9,40% chance stage 2 < 1% change stage 3 < 1% change stage 4
  • 14. Predicting waiting times or disease events
  • 15. Case of perioperative infections ▪ 234,000,000 surgical procedures / year ▪ 40% budget health care ▪ 1 in 4 patients get a complication ▪ Cost up 11.626 USD & HLOS up 114-150% Weiser Lancet 2008, Eapen JAMA 2013, Dimick AM J Coll Surg 2003, Gawande Surgery 1999
  • 16. Results: Predictive value Source: https://en.wikipedia.org/wiki/Precision_and_recall
  • 18. Wat is dit? All data classificatie dokter gebruikt analyse zoekt naar onzekere resultaten Stelt vragen Geeft feedback algoritme Active learning
  • 19. “I am afraid the doctor didn’t make it”
  • 20. ML will change health care ▪ Health and health care ▪ Prevent, diagnose, personalise ▪ Less hospital ▪ Enhance quality, and outcomes ▪ BUT ALWAYS IN COOPERATION
  • 21. Scyfer B.V. Science Park 400 1098 XH Amsterdam bart@scyfer.nl www.scyfer.nl I am looking for; -  Health CHALLENGES -  DATA -  Above all: Motivated and skilled PEOPLE