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Gary Phillips
External publications
1. Azzopardi D, Haswell L.E., Foss-Smith, G., Hewitt, K., Asquith, N., Corke S. and Phillips G. Evaluation of an
air-liquid interface cell culture model for studies on the inflammatory and cytotoxic responses to tobacco
smoke aerosols. Toxicology in vitro, 2015 (Accepted June 2015).
2. Baxter A, Thain S, Banerjee A, Haswell L, Parmar A, Phillips G, Minet E. Targeted omics analyses, and
metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term
cultures of reconstituted human airway epithelia. Toxicol In vitro. 2015 Aug;29(5):864-75.
3. Adamson J, Haswell, L.E., Phillips G and Gaca M. In vitro models of chronic obstructive lung disease.
Chapter 3, Bronchitis. Ed. Martin-Loeches, I. Pub. Intech. 2011.
4. Porter A, Phillips G, Smith L, Erwin-Cohen R, Tammariello R, Hale M, DaSilva L. Evaluation of a ricin vaccine
candidate (RVEc) for human toxicity using an in vitro vascular leak assay. Toxicon. 2011 Jul;58(1):68-75.
5. Ian Fearon, Gary Phillips, Tony Carr, Mark Taylor, Damien Breheny and Stephen Faux. The role of oxidative
stress in smoking-related diseases. Mini reviews in Organic Chemistry, 2011, 8, 4, 360-371.
6. Ferdousi Chowdhury, William J Howat, Gary Phillips, Peter M Lackie. Interactions between endothelial cells
and epithelial cells in a combined cell model of airway mucosa; effects on tight junction permeability. Lung
Research (August 2010).
7. Griffiths, GD; Phillips, GJ; Holley, J. Inhalation toxicology of ricin preparations: Animal models, prophylactic
and therapeutic approaches to protection. Inhalation Toxicology Vol. 19. Issue 10, P873. 2007.
8. Marsden, C.J., Knight, S., Smith, D.C., Day, P.J., Roberts, L.M., Phillips, G.J. and Lord J.M. Insertional
mutagenesis of ricin A chain: a novel route to an anti-ricin vaccine. Vaccine 22 (2004), pp2800 – 2805.
9. Griffiths, G.D., Phillips, G.J. and Bailey, S.C. Comparison of the quality of protection elicited by toxoid and
peptide liposomal vaccine formulations against ricin as assessed by markers of inflammation. Vaccine 17
(1999), pp2562 - 2568.
10. Jackson, AA., Phillips, G., McClelland I., and Jahoor, F. Synthesis of hepatic secretory proteins in normal
adults consuming a diet marginally adequate in protein. Am. J. Physiol. Gastrointest. Liver Physiol. 2001 Nov;
281(5)., G1179-87.
11. Jahoor, F., Jackson, A., Gazzard B., Phillips, G., Sharpstone, D., Frazer, M. and Heird, W. Erythrocyte
glutathione deficiency in symptom free HIV infection is associated with decreased synthesis rates. Am. J.
Physiol. 276: E205 - E211, 1999.
12. Jahoor, F., Gazzard B., Phillips, G., Sharpstone, D., Delrosario, M., Frazer, M., Heird, W. , Smith R. and
Jackson A. The acute phase protein response to human immunodeficiency virus infection in human subjects.
Am. J. Physiol. 276: E1092 - E1098, 1999.
13. Langley-Evans SC., Phillips GJ, Jackson AA. Fetal exposure to low protein maternal diet alters the
susceptibility of young adult rats to sulfur dioxide-induced lung injury. J.Nutr. 1997 Feb: 127(2): 202-9.
14. Langley-Evans, S.C., Phillips, G.J., Jackson, A.A. Sulphur dioxide: a potent glutathione depleting agent.
Comp. Biochem. Physiol. Pharmacol. Toxicol. Endocrinol. 1996 June, 114 (2), 89 - 98.
15. Langley-Evans, S.C., Phillips, G.J., Jackson, A.A. Fetal exposure to low maternal protein diet alters the
susceptibility of young rats to sulfur dioxide induced lung injury. J.Nutr 1997; Feb 127 (2), 202 - 209.
16. Langley-Evans SC, Phillips GJ, Benediktsson R, Gardner DS, Edwards CRW, Jackson AA, Seckl JR. Protein
intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat.
Placentae. 1996; Mar-Apr 17(2-3), 169 - 172.
17. Langley-Evans SC, Phillips GJ, Jackson AA. In utero exposure to maternal low protein diets induces
hypertension in weanling rats, independently of maternal blood pressure changes. Clin. Nutr. (1994); 13,
p319-324.
18. Kelly FJ, Phillips GJ. Role of inflammatory cells in hyperoxic-induced lung damage. Medical, biochemical and
chemical aspects of free radicals. Proceedings of the 4th
biennial meeting of the society for free radical
research, Kyoto, Japan. (1990), p1253-1256.
19. Kelly FJ, Town GI, Phillips GJ, Holgate ST, Roche WR, Postle AD. The preterm guinea pig: a model for the
study of neonatal lung disease. Clin. Sci. (1991); 81, p439-446.
20. Kelly FJ, Rickett GM, Phillips GJ. The magnitude of hyperoxic stress and degree of lung maturity determines
the nature of pulmonary antioxidant response in the guinea pig. Free. Rad. Res. Comms. (1992); 17(5), p335-
347.
21. Langley SC, Phillips GJ, Tahedl S, Kelly FJ. Dietary supplementation of vitamin E fails to prevent the
development of hyperoxic lung injury in the premature guinea pig. Comp. Biochem. Physiol. (1992); 103A(4),
p793-799.
22. Town GI, Phillips GJ, Landreau M, Louden J, Kelly FJ. Dexamethasone blunts hyperoxic-induced lung injury
and inflammation in the oxygen-exposed premature guinea pig. Biochem. Pharmacol. (1993); 46(9), p1565-
1572.
23. Kelly FJ, Phillips GJ. Neutrophil and oxygen-induced lung injury: a case of when a few is still too many.
Redox. Report. (1994); 1, p37-44.
24. Phillips GJ, Mohammed W, Kelly FJ. Oxygen-induced lung injury in the preterm guinea pig: The role of
leukotriene B4. Respir. Med 1995; Oct, 89(9), 607 -613.
25. Pai, V., Guz, A., Phillips, G.J., Cooke, N.T., Hutchinson, D.S. and Tetley, T.D. Urinary desmosine, elastolysis
and lung disease. Metabolism (1991); 40(2), p139-145.
26. Tetley, T.D., Guz, A., Fox, B. and Phillips, G.J. The Blotchy mouse, lung desmosine and emphysema. Annal.
N.Y. Acad. Sci. (1991); 624, p358.
27. McCartney, A.E., Fox, B., Partridge, T.A., MacRae, K.D., Tetley, T.D., Phillips, G.J. and Guz A. Emphysema
in the Blotchy mouse: A morphometric study. J.Pathol. (1988) 156, p77-81.
28. Wasil M, Phillips GJ, Hutchinson DCS, Hamilton EBD, Jawad A, Colville J, Baum H. Oxidative inactivation of
serum 1-protease inhibitor in emphysema and rheumatoid arthritis. Pulmonary emphysema and proteolysis
(1986), p435-444, Ed. J.C. Taylor and C. Mittman; Academic press.

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Publications

  • 1. Gary Phillips External publications 1. Azzopardi D, Haswell L.E., Foss-Smith, G., Hewitt, K., Asquith, N., Corke S. and Phillips G. Evaluation of an air-liquid interface cell culture model for studies on the inflammatory and cytotoxic responses to tobacco smoke aerosols. Toxicology in vitro, 2015 (Accepted June 2015). 2. Baxter A, Thain S, Banerjee A, Haswell L, Parmar A, Phillips G, Minet E. Targeted omics analyses, and metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term cultures of reconstituted human airway epithelia. Toxicol In vitro. 2015 Aug;29(5):864-75. 3. Adamson J, Haswell, L.E., Phillips G and Gaca M. In vitro models of chronic obstructive lung disease. Chapter 3, Bronchitis. Ed. Martin-Loeches, I. Pub. Intech. 2011. 4. Porter A, Phillips G, Smith L, Erwin-Cohen R, Tammariello R, Hale M, DaSilva L. Evaluation of a ricin vaccine candidate (RVEc) for human toxicity using an in vitro vascular leak assay. Toxicon. 2011 Jul;58(1):68-75. 5. Ian Fearon, Gary Phillips, Tony Carr, Mark Taylor, Damien Breheny and Stephen Faux. The role of oxidative stress in smoking-related diseases. Mini reviews in Organic Chemistry, 2011, 8, 4, 360-371. 6. Ferdousi Chowdhury, William J Howat, Gary Phillips, Peter M Lackie. Interactions between endothelial cells and epithelial cells in a combined cell model of airway mucosa; effects on tight junction permeability. Lung Research (August 2010). 7. Griffiths, GD; Phillips, GJ; Holley, J. Inhalation toxicology of ricin preparations: Animal models, prophylactic and therapeutic approaches to protection. Inhalation Toxicology Vol. 19. Issue 10, P873. 2007. 8. Marsden, C.J., Knight, S., Smith, D.C., Day, P.J., Roberts, L.M., Phillips, G.J. and Lord J.M. Insertional mutagenesis of ricin A chain: a novel route to an anti-ricin vaccine. Vaccine 22 (2004), pp2800 – 2805. 9. Griffiths, G.D., Phillips, G.J. and Bailey, S.C. Comparison of the quality of protection elicited by toxoid and peptide liposomal vaccine formulations against ricin as assessed by markers of inflammation. Vaccine 17 (1999), pp2562 - 2568. 10. Jackson, AA., Phillips, G., McClelland I., and Jahoor, F. Synthesis of hepatic secretory proteins in normal adults consuming a diet marginally adequate in protein. Am. J. Physiol. Gastrointest. Liver Physiol. 2001 Nov; 281(5)., G1179-87. 11. Jahoor, F., Jackson, A., Gazzard B., Phillips, G., Sharpstone, D., Frazer, M. and Heird, W. Erythrocyte glutathione deficiency in symptom free HIV infection is associated with decreased synthesis rates. Am. J. Physiol. 276: E205 - E211, 1999. 12. Jahoor, F., Gazzard B., Phillips, G., Sharpstone, D., Delrosario, M., Frazer, M., Heird, W. , Smith R. and Jackson A. The acute phase protein response to human immunodeficiency virus infection in human subjects. Am. J. Physiol. 276: E1092 - E1098, 1999. 13. Langley-Evans SC., Phillips GJ, Jackson AA. Fetal exposure to low protein maternal diet alters the susceptibility of young adult rats to sulfur dioxide-induced lung injury. J.Nutr. 1997 Feb: 127(2): 202-9. 14. Langley-Evans, S.C., Phillips, G.J., Jackson, A.A. Sulphur dioxide: a potent glutathione depleting agent. Comp. Biochem. Physiol. Pharmacol. Toxicol. Endocrinol. 1996 June, 114 (2), 89 - 98. 15. Langley-Evans, S.C., Phillips, G.J., Jackson, A.A. Fetal exposure to low maternal protein diet alters the susceptibility of young rats to sulfur dioxide induced lung injury. J.Nutr 1997; Feb 127 (2), 202 - 209. 16. Langley-Evans SC, Phillips GJ, Benediktsson R, Gardner DS, Edwards CRW, Jackson AA, Seckl JR. Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat. Placentae. 1996; Mar-Apr 17(2-3), 169 - 172. 17. Langley-Evans SC, Phillips GJ, Jackson AA. In utero exposure to maternal low protein diets induces hypertension in weanling rats, independently of maternal blood pressure changes. Clin. Nutr. (1994); 13, p319-324. 18. Kelly FJ, Phillips GJ. Role of inflammatory cells in hyperoxic-induced lung damage. Medical, biochemical and chemical aspects of free radicals. Proceedings of the 4th biennial meeting of the society for free radical research, Kyoto, Japan. (1990), p1253-1256. 19. Kelly FJ, Town GI, Phillips GJ, Holgate ST, Roche WR, Postle AD. The preterm guinea pig: a model for the study of neonatal lung disease. Clin. Sci. (1991); 81, p439-446.
  • 2. 20. Kelly FJ, Rickett GM, Phillips GJ. The magnitude of hyperoxic stress and degree of lung maturity determines the nature of pulmonary antioxidant response in the guinea pig. Free. Rad. Res. Comms. (1992); 17(5), p335- 347. 21. Langley SC, Phillips GJ, Tahedl S, Kelly FJ. Dietary supplementation of vitamin E fails to prevent the development of hyperoxic lung injury in the premature guinea pig. Comp. Biochem. Physiol. (1992); 103A(4), p793-799. 22. Town GI, Phillips GJ, Landreau M, Louden J, Kelly FJ. Dexamethasone blunts hyperoxic-induced lung injury and inflammation in the oxygen-exposed premature guinea pig. Biochem. Pharmacol. (1993); 46(9), p1565- 1572. 23. Kelly FJ, Phillips GJ. Neutrophil and oxygen-induced lung injury: a case of when a few is still too many. Redox. Report. (1994); 1, p37-44. 24. Phillips GJ, Mohammed W, Kelly FJ. Oxygen-induced lung injury in the preterm guinea pig: The role of leukotriene B4. Respir. Med 1995; Oct, 89(9), 607 -613. 25. Pai, V., Guz, A., Phillips, G.J., Cooke, N.T., Hutchinson, D.S. and Tetley, T.D. Urinary desmosine, elastolysis and lung disease. Metabolism (1991); 40(2), p139-145. 26. Tetley, T.D., Guz, A., Fox, B. and Phillips, G.J. The Blotchy mouse, lung desmosine and emphysema. Annal. N.Y. Acad. Sci. (1991); 624, p358. 27. McCartney, A.E., Fox, B., Partridge, T.A., MacRae, K.D., Tetley, T.D., Phillips, G.J. and Guz A. Emphysema in the Blotchy mouse: A morphometric study. J.Pathol. (1988) 156, p77-81. 28. Wasil M, Phillips GJ, Hutchinson DCS, Hamilton EBD, Jawad A, Colville J, Baum H. Oxidative inactivation of serum 1-protease inhibitor in emphysema and rheumatoid arthritis. Pulmonary emphysema and proteolysis (1986), p435-444, Ed. J.C. Taylor and C. Mittman; Academic press.