The document summarizes 25 projects that were finalists for the INFORMS (ISMS Society for Marketing Science) Practice Prize competition from 2003 to 2012. The prize recognizes impactful implementations of marketing science concepts and methods in organizations. The article reviews common factors among the projects, clusters them into groups, develops a framework for successful marketing science model development and application, and discusses insights into how models diffuse and have impact. Key findings include that effective applications span a wide range of problems and techniques, and there are multiple paths to success, including simpler models that provide robust results. Organizational buy-in is critical and can be achieved through various means. Intermediaries often play an important role in introducing and spreading models across organizations.