1. MARIA FELICIA BOGDAN, Ph.D.
Professional Address Home Address
Abbott Laboratories 5046 Red Pine Ave
100 Abbott Park Rd Gurnee, IL 60031
Bldg. AP20-3 (773)- 885- 3165
Abbott Park, IL 60064
felicia.bogdan@abbott.com
CAREER OBJECTIVE
Apply my technical and leadership skills to help advance health and medicine thru innovation and
strategic partnerships.
EXPERTISE
TECHNICAL LEADERSHIP
Organic synthesis Set vision/strategy (Employee Network)
Bioconjugation Build Employee Network
Protein/Peptide/Peptidomimetics Initiated and developed strategic
partnerships
Nucleic acids (TEDMED Employee network/ Abbott
Analytical techniques Organizations)
Process development Build technical cross- functional
teams
Process transfer Mentor
PROFESSIONAL EXPERIENCE
2008- present Principal Scientist
R&D Process Design, Bioconjugation
Abbott Laboratories, Abbott Park, IL
• Conceived, designed, planned and conducted experiments for the preparation of
antibody/antigen/peptide bioconjugates for immunodiagnostic assays (ARCHITECT
Testosterone, Pre-eclampsia, Methotrexate, IL18, HCV Combo).
• Developed processes for the preparation of bioconjugates.
• Contributed to the development of bioconjugation best practices.
• Presented bioconjugation findings at cross- functional team meetings, R&D
Technical Reviews and division/corporate Science Exchange poster sessions.
• Provided bioconjugation SME to the R&D organization.
• Provided bioconjugation/chemistry expertise to support selection of future
immunodiagnostic technologies and secure Abbott intellectual property.
2006- 2008 Senior Scientist
R&D Process Design, Bioconjugation
Abbott Laboratories, Abbott Park, IL
• Conceived, designed, planned and prepared protein conjugates for
immunodiagnostic assays, protein/antibody selection and biomolecular binding
studies (ARCHITECT NGAL, B12, Pre-eclampsia, and Testosterone).
• Developed processes for preparation of bioconjugates and transferred to Abbott
manufacturing and TPM (Fisher, Fujirebio).
• Developed a small scale bioconjugation approach to minimized consumption of
expensive raw material, leading to a significant reduction in project cost.
• Trained TPM personnel (Fujirebio) on bioconjugation techniques and laboratory
equipment use.
• Presented bioconjugation results at cross- functional team meetings, management
reviews and Abbott Science Exchange poster sessions.

2. Maria Felicia Bogdan, Ph.D.
• Provided bioconjugation technical expertise to R&D teams.
• Developed rapports with Abbott vendors to ensure high quality and proper
characterization of incoming raw materials, availability of sufficient supply and
timely delivery for production (R&D Systems, SoluLink, ThermoFisher).
2002- 2005 Senior Scientist
R&D Organic Chemistry
Abbott Laboratories, Abbott Park, IL
• Designed and synthesized organic reagents for the development of
immunodiagnostic assays (ARCHITECT Sirolimus, Vitamin B12, Peptoid labels for
Signal Amplification).
• Developed a process for the Sirolimus tracer as a reagent for therapeutic blood
drug monitoring following an organ transplant; supported process transfer to the
TPM (AMRI).
• Developed methods for chromatographic analyses of organic reagents/polymers
(e.g., Glycated hemoglobin) and for the optimization of an enzymatic reaction
critical to the successful development of a cardiac immunoassay (Homocysteine).
• Maintained group mass spectrometer.
1999- 2002 Postdoctoral Fellow - NIH-NHGRI
Northwestern University, Evanston, IL
Advisor: Annelise E. Barron, Ph.D.
Department of Chemical and Biomedical Engineering
• Conducted research aimed at developing a rapid, low cost, high-throughput DNA
sequencing technique based upon end-label free solution capillary
electrophoresis (ELFSE) that should allow analysis of long DNA in the absence of a
polymer matrix.
• Devised and synthesized a novel class of “end-label” (EL) structures
encompassing unnatural peptides and peptidomimetics chemically assembled
into linear and branched architectures and attached to DNA primers.
• Performed characterization of group synthesized polymers and copolymers to
serve as sieving matrices for high-throughput DNA sequencing and DNA mutation
detection.
• Trained and supervised undergraduate and graduate students in performing
organic synthesis.
1991- 1992 Chemistry/Physics Teacher
Textile High School, Romania
• Taught High School Chemistry and Physics (German language).
ADDITIONAL PROFESSIONAL ACCOMPLISHMENTS
2013- 2014 Chair, Abbott Women in Science employee network (AWS)
Abbott Laboratories
• Developed the vision, strategy, and tactics to address Abbott business and
scientist needs.
• Secured executive sponsorship and build partnerships with Abbott Organizations
(Global Citizenship, Abbott Fund, Scientific Governing Board, and HR).
• Build AWS organization committees.
• Led the expansion of the network outside the US (EU).
• Developed programs, some of which are being implemented across Abbott
globally (e.g., Scientist Mentoring Circles, new “Operation Discovery” STEM
outreach experiments).
• Increased AWS’s membership from 260 (US only) to 430 members (US and EU).
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3. Maria Felicia Bogdan, Ph.D.
2012- Present Spearhead, Abbott/TEDMED Partnership
Abbott Laboratories
• Initiated, led and executed an ongoing Abbott partnership with TEDMED.
• Secured sponsorship funds thru a cross- divisional R&D collaboration.
• Connected Abbott and TEDMED Leadership, which led to Abbott becoming one of
the first TEDMED Global Partners (2014).
• Developed partnerships with Abbott Corporate Marketing organizations to ensure
branding/strategy alignment and secure internal/external communication support.
• Helped connect the Abbott and TEDMED communities via TEDMEDLive.
• Organized and led the Abbott delegation to TEDMED (2012, 2013, and 2015).
• Initiated and provided Abbott nutritional products for the TEDMED conference
(Health Snack Program).
EDUCATION
1995- 1999 Ph.D., Organic Chemistry
Wayne State University, Detroit, MI
Dissertation: Approaches towards the site- specific incorporation of modified
nucleosides into oligonucleotides.
Advisor: Christine S. Chow, PhD
Department of Biochemistry
1993- 1995 Ph.D. Candidate, Organic Chemistry
Wayne State University, Detroit, MI
Project: Studies towards the synthesis of novel chemiluminesc ent dioxetan es.
Advisor: Arthur P. Schaap, PhD
Department of Organic Chemistry
1988- 1991 B.Sc., Major: Chemistry; Minor: Physics
Babeș -Bolyai University , Cluj-Napoca, Romania
Advisor: Dr. Francisc Kacso
AWARDS, HONORS, RECOGNITIONS, AFFILIATIONS
• Awarded membership, Healthcare Businesswomen Association - HBA (2015)
• Abbott Global Diagnostics Product Development – Team Cornerstone Award (2015)
• Abbott Global Diagnostics R&D Top Performer Award – Life Science Research Team of the Year
(2012)
• Abbott Women in Science Innovation Award for initiating an Abbott/TEDMED Partnership (2012)
• Abbott CEO Recognition for supporting Abbott STEM outreach (Abbott Women in Science
Network, 2011)
• Abbott Diagnostics President Team Award (2007)
• NIH-NHGRI National Research Service Award (Postdoctoral Fellowship #1 F32 HG-02337) (2001)
• Member, Phi Lambda Upsilon, National Honorary Chemical Society (1997)
• Member, American Chemical Society (1994- 1997)
• Elected Treasurer, Babe Bolyai University, Department of Chemistry and Chemical Engineeringș
(1990)
• Group leader, Babe Bolyai University, Department of Chemistry and Chemical Engineeringș
(1989, 1990)
• Elected Vice-President, Babe Bolyai University, Department of Chemistry and Chemicalș
Engineering (1989)
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4. Maria Felicia Bogdan, Ph.D.
PATENTS
RELATED TO USE OF STOICHIOMETRIC CONJUGATES FOR USE IN NANOPORE BASED IMMUNOASSAY‐
DETECTION SYSTEMS. Jeff Huff, Mark Hayden, Anthony Muerhoff, Felicia Bogdan , Tom Leary,
Shelley Hollets McCormack, Sophie Lorenson. Abbott Reference No. 12496USL1; US Provisional‐
Application.
Filed April 3, 2015, Serial No. 62/142,872 (Atty. Docket: ADDV 035PRV)‐
RELATED TO USE OF STOICHIOMETRIC CONJUGATES FOR USE IN NANOPORE BASED IMMUNOASSAY‐
DETECTION SYSTEMS. Jeff Huff, Mark Hayden, Anthony Muerhoff, Felicia Bogdan , Tom Leary,
Shelley Hollets McCormack, Sophie Lorenson. Abbott Reference No. 12496USL1A; US Provisional‐
Application.
Filed July 1, 2015, Serial No. 62/187,704 (Atty. Docket: ADDV 035PRV)‐
HCV NS3 RECOMBINANT ANTIGENS AND MUTANTS THEREOF FOR IMPROVED ANTIBODY DETECTION.
S. Muerhoff, C. Marohnic, L. Birkenmeyer, J. Prostko, F. Bogdan , R. Gutierrez, US 20140272932 A1.
Filed December 23, 2013. Published: September 18, 2014.
PUBLICATIONS
Haynes, RD; Meagher RJ; Won JI, Bogdan MF, Barron AE.: “Comblike, monodisperse polypeptoid
drag-tags for DNA separations by end-labeled free- solution electrophoresis (ELFSE).” Bioconjugate
Chemistry , 2005 , 16 (4), 929- 938.
Brett A. Buchholz, Erin A.S. Doherty, Methal N. Albarghouthi, Felicia M. Bogdan , Jacob M. Zahn,
Annelise E. Barron: “Microchannel DNA Sequencing Matrices with a Thermally-Controlled ‘Viscosity
Switch’.” Analytical Chemistry, 2000 , 73 (2), 157- 164.
Methal N. Albarghouthi, Brett A. Buchholz, Erin A.S. Doherty, Felicia M. Bogdan , Haihong Zhou,
Annelise E. Barron: “Impact of Polymer Hydrophobicity on the Properties and Performance of DNA
Sequencing Matrices for Capillary Electrophoresis.” Electrophoresis , 2001 , 22, 737- 747.
Felicia M. Bogdan ; Christine S. Chow: “The Synthesis of Allyl- and Allyloxycarbonyl-Protected RNA
Phosphoramidites. Useful Reagents for Solid-Phase Synthesis of RNAs with Base- Labile
Modifications”, Tetrahedron Letters 1998 , 39, 1897- 1900.
Christine S. Chow; Felicia M. Bogdan : “A Structural Basis for RNA-Ligand Interactions” Chemical
Reviews , 1997 , 97(5), 1489- 1513.
POSTERS (select)
Engineering of the Hepatitis C Virus Helicase for Enhanced Immunoreactivity . Christopher
Marohnic, Larry Birkenmeyer, Felicia Bogdan , Edwin Frias, Kathleen Otis, MaryAnn Palafox, Troy
McSherry, Svetoslava Gregory, Cheng Zhao, Robin Gutierrez, George Dawson, John Prostko, & A.
Scott Muerhoff. 21st International Symposium on Hepatitis C and Related Viruses, September 2014.
HCV Ag/Ab Combo Assay – Antigen Conjugates for HCV Antibody Detection. M. Felicia Bogdan,
Robin Gutierrez, Kevin Cheng, MaryAnn Palafox, Mark Pope, George Dawson. Abbott Diagnostics
Day of Science and Technology, May 2012.
HCV Ag/Ab Combo Assay – Antigen Conjugates for HCV Antibody Detection. M. Felicia Bogdan,
Robin Gutierrez, Svetoslava Gregory, Panfilo Ozeata, George Dawson, Mark Pope. Abbott Day of
Science and Technology, November 2011.
Advances in Protein Biotinylation: From Alkyl-Biotin to UV-Active Biotin Protein Conjugates. M.
Felicia Bogdan, Todd Solbrig, John Ramp. Abbott Technology Exchange, October 2008.
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5. Maria Felicia Bogdan, Ph.D.
Design, Development and Characterization of rhPlGF-Acridinium Bioconjugates for the ARCHITECT
sFlt1 Assay. M. Felicia Bogdan , George Yu. Abbott Technology Exchange, September 2006.
Enzymatic Synthesis of S-Adenosyl-L-Homocsyteine: M. Felicia Bogdan, Rajarathnam E. Reddy.
Abbott Technology Exchange, September 2005.
Synthesis of Sirolimus Fluorescein Tracers and Their Evaluation in an ARCHITECT Bihapten Assay
Format: M. Felicia Bogdan, Sushil D. Rege, Donald D. Johnson, Rajarathnam E. Reddy, Ryan
Workman, Frank Grenier. Abbott Technology Exchange, September 2004.
Synthesis of Sirolimus Tracers for the Development of an ARCHITECT Sirolimus Immunoassay: M.
Felicia Bogdan, Jeff A. Moore, Rajarathnam E. Reddy, Sushil D. Rege. Abbott Technology
Exchange, September 2003.
Synthesis and Solid-Phase Incorporation of N4
-acetylcytidine into Oligoribonucleotides Using an
Allylic Protection Strategy: Felicia M. Bogdan , Christine S. Chow. Gordon Research Conference,
Bioorganic Division, June 14 th
, 1998, Andover, NH.
Synthesis of Allyl- and Allyloxycarbonyl Protected Ribonucleotide Phosphoramidites: Felicia M.
Bogdan , Christine S. Chow. Parke-Davis Poster Session, May 21 st
, 1997, Wayne State University,
Detroit, MI.
5

6. Maria Felicia Bogdan, Ph.D.
Design, Development and Characterization of rhPlGF-Acridinium Bioconjugates for the ARCHITECT
sFlt1 Assay. M. Felicia Bogdan , George Yu. Abbott Technology Exchange, September 2006.
Enzymatic Synthesis of S-Adenosyl-L-Homocsyteine: M. Felicia Bogdan, Rajarathnam E. Reddy.
Abbott Technology Exchange, September 2005.
Synthesis of Sirolimus Fluorescein Tracers and Their Evaluation in an ARCHITECT Bihapten Assay
Format: M. Felicia Bogdan, Sushil D. Rege, Donald D. Johnson, Rajarathnam E. Reddy, Ryan
Workman, Frank Grenier. Abbott Technology Exchange, September 2004.
Synthesis of Sirolimus Tracers for the Development of an ARCHITECT Sirolimus Immunoassay: M.
Felicia Bogdan, Jeff A. Moore, Rajarathnam E. Reddy, Sushil D. Rege. Abbott Technology
Exchange, September 2003.
Synthesis and Solid-Phase Incorporation of N4
-acetylcytidine into Oligoribonucleotides Using an
Allylic Protection Strategy: Felicia M. Bogdan , Christine S. Chow. Gordon Research Conference,
Bioorganic Division, June 14 th
, 1998, Andover, NH.
Synthesis of Allyl- and Allyloxycarbonyl Protected Ribonucleotide Phosphoramidites: Felicia M.
Bogdan , Christine S. Chow. Parke-Davis Poster Session, May 21 st
, 1997, Wayne State University,
Detroit, MI.
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