Presentation by Don King from The Pirbright institute to the 42nd General Session of the EuFMD, 20-21 April 2017
http://www.fao.org/ag/againfo/commissions/eufmd/commissions/eufmd-home/reports/general-sessions/en/
GS42 Information session: current FMD situation in Israel, by T.Goshen (Is)
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Foot & Mouth Disease
in Israel 2017
Tamir Goshen
Israeli Veterinary Field Services Director
42nd General Session of the EuFMD
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• Vaccine strains (Pool 3):
- Type O contains antigens: Manisa, Geshur 85 (O4625 ), O–3039, O
Panasia 2.
- Type A contains antigens: A- 4165 + A Iran 2005.
- Type Asia1 contains antigen: Asia 1 Shamir. (cattle only)
FMD Control
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FMD control 2014-6
annual vaccination (average)Animal
707,158Cattle
953,415Sheep & Goats
• Over all ~ 98.5% of registered herd were vaccinated
in 2016.
• FMD vaccination is mandatory and done by the IVS.
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Outbreak by Index case Month (1974-2017)
0
1
2
3
4
5
6
7
8
#offirstOtbreaks
Month
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Historical Israeli FMD Outbreaks
FMD 2011
FMD 2014
Snir
Cattle O
FMD 2011
Beit Zera
Cattle O
FMD 2012
Rafah GS
SAT2
FMD 2014
Uga, Tira, Iksal
Sheep O
FMD 2007
Neve-Ur
Cattle O
FMD 2007
Netua
Goats O
FMD 2015
Fasuta, Nablus
Pigs O
FMD 2009
Beit Halevi cattle
Kfar Yehoshua
Goats A
FMD 2006
Dir Samet WB
Cattle O
FMD 2017
Nir Yitzhak cattle
& GS O
Sheep & cattle 10 Km from border
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• First major outbreak in a dairy farm in years.
• Israeli farms are vaccinated annually from October,
young stock is vaccinated 3-5 m with booster 3 m later.
Nir Yitzhak:
• 775 cows & heifers.
• The cows were vaccinated 1 year beafore.
• Replacement heifers – at 2-4 m and boostered 3 m later.
FMD Outbreak in Dairy Farm – Nir Yitzhak
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Outbreak area
Farms in 10 km radius:
Holit – dairy farm.
Nir Oz- Cattle Feedlot.
Magen – Replacement dairy
heifers .
Nave – sheep farm.
Pri Gan - sheep farm.
Talmei Yosef - sheep farm.
Eshcolot - sheep farm.
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Nir Yitzhak
Nir Yitzhak
3.9 Km
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Nir Yitzhak Dairy farm
Nir Yitzhak
Road232
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Suckling
calves 0-
2 m
Nir Yitzhak Dairy farm
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Possible Incursion
• Air born.
• Nearby road (232).
• IDF border patrols.
• Other – wild animals; animal traders ect.
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Morbidity by group
Morbidity Rate# cases# animalsAgeGroup
9.8%4410 – 2 mHutches
50%20402 – 4 mweaning
7.5%6804 – 18 mReplacement
39.8%4110318 m +Pregnant Heifers
61.5%59962 years +1st Calf Heifers
33.3%31933 years +2nd Lactation
37.8%34904 years +3rd + lactation (B)
27.2%281034 years +3rd + lactation (C)
40.9%1844mixedLow producers (D)
2.2%1453 years +Dry cows
27.5%11403 years +Close up
32.6%253775Overall
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Mortality
• 8 cows & 1 pregnant heifer.
• Deaths due to secondary infections, mainly
mastitis and septic arthritis.
• No mortality in young calves or heifers.
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• Milk production loss.
• Inability to sell cows and bull calves.
• Crowding.
• Diseased cows that healed and did not return to milk
(w/o secondary infections; ~ 10 cows)
Indirect losses
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KVI Virus typing
Vaccine matchingVp1 SequancingRT-PCRELISAOutbreak Location
UnavailableSerotype O
O/EA -3 Topotype
~90% identity to
recent isolates in
Egypt and Sudan
Serotype OSerotype ONir Yitzhak
UnavailableSerotype O
O/EA -3 Topotype
~90% identity to
recent isolates in
Egypt and Sudan
Serotype OSerotype OGaza Strip
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Pirbright genotyping
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Pirbright genotyping
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• Prioritization of Vaccination order (October-
November):
─ 10 Km from border.
─ 10 km from exporting dairy factories.
• Exportation of cattle vaccinated twice to the GS.
• Vaccine efficacy - poor matching but efficient
vaccinaton?
Conclusions
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• Periodical meetings and coordination.
• Information exchange.
• Diagnosis in the KVI.
• FAO visits and workshops.
Collaboration with the PA
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• Continued collaboration with the PA in the current
format:
─ Joined workshops.
─ Active surveillance.
• Local, regional importance.
• Importance to the EU.
Future challenges
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Acknowledgment
• Dr. N. Galon.
• Dr. Michel Bellaiche
• Prof. Eyal Klement
• Dr. Boris Gelman
• KVI & VS workers
• The FAO / EuFMD.
Thanks