14th Experts Live CTO
September 2nd - 3rd, 2022 - Mainz, Germany
Main Session - Lunch Symposium by Asahi:
Road to CTO expert 2022 – how to build your CTO toolkit
When the “uncrossable” becomes crossable
Gregor Leibundgut, Bâle, Suisse
Room:
Guteberg Hall (Auditorium) - Saturday 13:30
Speaker:
Gerald Werner, Darmstadt, Germany;
Kambis Mashayekhi, Lahr, Germany;
Jo Dens, Genk, Belgium;
Gregor Leibundgut, Bâle, Suisse
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Gregor Leibundgut: When the “uncrossable” becomes crossable
1. 14th Experts Live CTO
The annual Euro CTO meeting
September 2nd - 3rd, 2022. Mainz, Germany
Road to CTO expert 2022 – how to build your CTO toolkit
When the “uncrossable” becomes crossable
Lunch Symposium by Asahi
EURO CTO CLUB
Gregor Leibundgut, MD
University Hospital Basel, Switzerland
3. Uncrossable Proximal Cap
Power Knuckle
Carlino
(hydrolic dissection)
BASE
Side-BASE
Scratch & Go
Dual Lumen Microcatheter
Support Puncture
Power Puncture
12. The Knuckle-wire Technique
Knuckling
• The knuckle technique is used to
create a deliberate blunt dissection
plane in various CTO techniques.
• The guidewire, usually a polymer-
jacketed guidewire, is pushed until
a complex loop is formed and
advanced through the lesion
13. When should we knuckle?
Knuckling
• Antegrade dissection Re-entry (ADR)
- Whenever the wire escalation strategy (parallel wiring) failed
- In tortuous anatomy
- Ambiguous vessel course
- Ideally NO sidebranches
- NO distal bifurcation
• Retrograde dissection Re-entry (RDR)
- Preferably do retrograde knuckling (safer, more predictable)
- Modified reverse CART (controlled antegrade and retrograde subintimal tracking)
14. Tip load is a function of the core wire
Knuckling
10mm
gap
15. Guidewire Tips
Knuckling
• non-tapered & round tip
- Workhorse wires
• non-tapered & pointed tip
- Gaia family
- Pilot 200
• tapered & round tip
- Fielder XT, XT-A, XT-R
- Confianza Pro 12
• tapered & pointed tip
- Stingray wire
23. After Knuckling
Knuckling
• The knuckle permanently deforms
the guide wire due to a bend in the
core wire
• Gladius MG is the only guidewire
that can be reused for regular
wiring after knuckling (e.g. tip-in)
24. Gladius EX
• Non-tapered, ACT ONE
• Tip load 3.0 g
• Tip radiopacity 3.0 cm
• Polymer jacket: 40 cm
Gladius MG
Knuckling
Gladius MG
• Non-tapered, ACT ONE
• Tip load 3.0 g
• Tip radiopacity 3.0 cm
• Polymer jacket: 41 cm
• Knuckle point at 8 mm
Preshaped micro-bend (similar to Gaia family)
“Knuckle point”
25. Key feature: Micro gap
The micro gap
0.
100.
200.
300.
400.
500.
1.5 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Load
(mN)
Distance from the tip (mm)
Comparison of tip rigidity
Gladius MG
PILOT200
8 mm
300 mN
30 mm
250 mN
41. WHAT CAN GO WRONG?
Space Shuttle Columbia, February 1st 2003
42. Precautions
What can go wrong on re-entry?
• Never spin the knuckled guidewire → creates a knot
• Knuckles tend to go into side branches → risk of perforation
• Big knuckles can weaken/rupture the vessel
• Small knuckles can cause distal perforations
• Knuckles with non-polymeric wires, especially penetration wires can
damage the microcatheter on retrieval and get stuck.
• In general, knuckles cause large subintimal hematomas
- Block antegrade flow, Do NOT inject antegradely, STRAW