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ANALGESICS IN DENTISTRYANALGESICS IN DENTISTRY
DEFINITIONDEFINITION
ALGESIAALGESIA :: IT IS DEFINED AS AN ILL DEFINED,IT IS DEFINED AS AN ILL DEFINED,
UNPLEASANT SENSATION, USUALLY EVOKED BY ANUNPLEASANT SENSATION, USUALLY EVOKED BY AN
EXTERNAL OR INTERNAL NOXIOUS STIMULI.EXTERNAL OR INTERNAL NOXIOUS STIMULI.
ANALGESICANALGESIC : A DRUG THAT SELECTIVELY RELIEVES: A DRUG THAT SELECTIVELY RELIEVES
PAIN BY ACTING IN THE CNS OR PERIPHERAL PAINPAIN BY ACTING IN THE CNS OR PERIPHERAL PAIN
MECHANISM,WITHOUT SIGNIFICANTLY ALTERING THEMECHANISM,WITHOUT SIGNIFICANTLY ALTERING THE
CONCIOUSNESS.CONCIOUSNESS.
PARACETAMOL / ACETAMINOPHEN (PANADOL)PARACETAMOL / ACETAMINOPHEN (PANADOL)
• NO ANTI INFLAMMATORY ACTIONNO ANTI INFLAMMATORY ACTION
• MODERATE ANTIPYRETICMODERATE ANTIPYRETIC
• DOES NOT CAUSE GIT IRRITATION /DOES NOT CAUSE GIT IRRITATION /
BLEEDING TIMESBLEEDING TIMES
• DOSE : 1000MG 6 HOURLYDOSE : 1000MG 6 HOURLY
MEFENAMIC ACID (PONSTAN)MEFENAMIC ACID (PONSTAN)
• MILD-MODERATE PAINMILD-MODERATE PAIN
• MUST BE TAKEN WITH FOODMUST BE TAKEN WITH FOOD  GITGIT
UPSETUPSET
• DOSE : 250MG-500MGDOSE : 250MG-500MG
ASPIRINASPIRIN
• MILD TO MODERATE PAINMILD TO MODERATE PAIN
• POTENT ANTIPYRETICPOTENT ANTIPYRETIC
• CONTRAINDICATIONCONTRAINDICATION  GIT ULCERATIONGIT ULCERATION
AND CONCURRENT ANTICOAGULANTAND CONCURRENT ANTICOAGULANT
• DOSE : 600-900MG 4 HOURLYDOSE : 600-900MG 4 HOURLY
IBUPROFENIBUPROFEN
• MILD-MODERATE PAINMILD-MODERATE PAIN
• MODERATE ANTIPYRETICMODERATE ANTIPYRETIC
• LESS IRRITANT TO THE GUTLESS IRRITANT TO THE GUT
• DOSE : 400-600MG 8 HOURLYDOSE : 400-600MG 8 HOURLY
ETORICOXIB (ARCOXIA)ETORICOXIB (ARCOXIA)
• RAPID ONSET ANDRAPID ONSET AND
LONG-LASTINGLONG-LASTING
PAIN RELIEFPAIN RELIEF
• 120 MG MINIMUM120 MG MINIMUM
POST DENTAL OPPOST DENTAL OP
MORPHINEMORPHINE
• MANAGEMENT OF TERMINAL PAINMANAGEMENT OF TERMINAL PAIN
• SEVERE PAINSEVERE PAIN  POST-OPPOST-OP
• DOSE : 10-20 MG 4 HOURLYDOSE : 10-20 MG 4 HOURLY
CODEINECODEINE
• DROWSINESS, GIT UPSETDROWSINESS, GIT UPSET
• FORMULATED WITH OTHER DRUGSFORMULATED WITH OTHER DRUGS 
ASPIRIN OR ACETAMINOPHENASPIRIN OR ACETAMINOPHEN
• DOSE 30 MG OF CODEIN + 600 MGDOSE 30 MG OF CODEIN + 600 MG
OF ASPIRINOF ASPIRIN
PREGNANT WOMENPREGNANT WOMEN
PATIENT WITH GIT ULCERPATIENT WITH GIT ULCER
• AVOID NSAIDAVOID NSAID  PREFERABLEPREFERABLE
PARACETAMOLPARACETAMOL
ANALGESICS FORANALGESICS FOR
CHILDRENCHILDREN
REFERENCEREFERENCE
• LAURA MITCHELL, DAVID A.MITCHELL. 2010. OXFORD HANDBOOK OFLAURA MITCHELL, DAVID A.MITCHELL. 2010. OXFORD HANDBOOK OF
CLINICAL DENTISTRY. 5CLINICAL DENTISTRY. 5THTH
EDITION. 560-562EDITION. 560-562
• MALMSTROM K ET AL. 2004.MALMSTROM K ET AL. 2004. ETORICOXIB IN ACUTE PAIN ASSOCIATED WITH
DENTAL SURGERY: A RANDOMIZED, DOUBLE-BLIND, PLACEBO- AND ACTIVE
COMPARATOR-CONTROLLED DOSE-RANGING STUDY. 26(5):667-679
• PAEDIATRIC ANALGESIA GUIDELINES. JUNE 2017. ROYAL CORNWALLPAEDIATRIC ANALGESIA GUIDELINES. JUNE 2017. ROYAL CORNWALL
HOSPITALSHOSPITALS

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Analgesics in dentistry

  • 2. DEFINITIONDEFINITION ALGESIAALGESIA :: IT IS DEFINED AS AN ILL DEFINED,IT IS DEFINED AS AN ILL DEFINED, UNPLEASANT SENSATION, USUALLY EVOKED BY ANUNPLEASANT SENSATION, USUALLY EVOKED BY AN EXTERNAL OR INTERNAL NOXIOUS STIMULI.EXTERNAL OR INTERNAL NOXIOUS STIMULI. ANALGESICANALGESIC : A DRUG THAT SELECTIVELY RELIEVES: A DRUG THAT SELECTIVELY RELIEVES PAIN BY ACTING IN THE CNS OR PERIPHERAL PAINPAIN BY ACTING IN THE CNS OR PERIPHERAL PAIN MECHANISM,WITHOUT SIGNIFICANTLY ALTERING THEMECHANISM,WITHOUT SIGNIFICANTLY ALTERING THE CONCIOUSNESS.CONCIOUSNESS.
  • 3.
  • 4. PARACETAMOL / ACETAMINOPHEN (PANADOL)PARACETAMOL / ACETAMINOPHEN (PANADOL) • NO ANTI INFLAMMATORY ACTIONNO ANTI INFLAMMATORY ACTION • MODERATE ANTIPYRETICMODERATE ANTIPYRETIC • DOES NOT CAUSE GIT IRRITATION /DOES NOT CAUSE GIT IRRITATION / BLEEDING TIMESBLEEDING TIMES • DOSE : 1000MG 6 HOURLYDOSE : 1000MG 6 HOURLY
  • 5. MEFENAMIC ACID (PONSTAN)MEFENAMIC ACID (PONSTAN) • MILD-MODERATE PAINMILD-MODERATE PAIN • MUST BE TAKEN WITH FOODMUST BE TAKEN WITH FOOD  GITGIT UPSETUPSET • DOSE : 250MG-500MGDOSE : 250MG-500MG
  • 6. ASPIRINASPIRIN • MILD TO MODERATE PAINMILD TO MODERATE PAIN • POTENT ANTIPYRETICPOTENT ANTIPYRETIC • CONTRAINDICATIONCONTRAINDICATION  GIT ULCERATIONGIT ULCERATION AND CONCURRENT ANTICOAGULANTAND CONCURRENT ANTICOAGULANT • DOSE : 600-900MG 4 HOURLYDOSE : 600-900MG 4 HOURLY
  • 7. IBUPROFENIBUPROFEN • MILD-MODERATE PAINMILD-MODERATE PAIN • MODERATE ANTIPYRETICMODERATE ANTIPYRETIC • LESS IRRITANT TO THE GUTLESS IRRITANT TO THE GUT • DOSE : 400-600MG 8 HOURLYDOSE : 400-600MG 8 HOURLY
  • 8. ETORICOXIB (ARCOXIA)ETORICOXIB (ARCOXIA) • RAPID ONSET ANDRAPID ONSET AND LONG-LASTINGLONG-LASTING PAIN RELIEFPAIN RELIEF • 120 MG MINIMUM120 MG MINIMUM POST DENTAL OPPOST DENTAL OP
  • 9. MORPHINEMORPHINE • MANAGEMENT OF TERMINAL PAINMANAGEMENT OF TERMINAL PAIN • SEVERE PAINSEVERE PAIN  POST-OPPOST-OP • DOSE : 10-20 MG 4 HOURLYDOSE : 10-20 MG 4 HOURLY
  • 10. CODEINECODEINE • DROWSINESS, GIT UPSETDROWSINESS, GIT UPSET • FORMULATED WITH OTHER DRUGSFORMULATED WITH OTHER DRUGS  ASPIRIN OR ACETAMINOPHENASPIRIN OR ACETAMINOPHEN • DOSE 30 MG OF CODEIN + 600 MGDOSE 30 MG OF CODEIN + 600 MG OF ASPIRINOF ASPIRIN
  • 11.
  • 13. PATIENT WITH GIT ULCERPATIENT WITH GIT ULCER • AVOID NSAIDAVOID NSAID  PREFERABLEPREFERABLE PARACETAMOLPARACETAMOL
  • 15. REFERENCEREFERENCE • LAURA MITCHELL, DAVID A.MITCHELL. 2010. OXFORD HANDBOOK OFLAURA MITCHELL, DAVID A.MITCHELL. 2010. OXFORD HANDBOOK OF CLINICAL DENTISTRY. 5CLINICAL DENTISTRY. 5THTH EDITION. 560-562EDITION. 560-562 • MALMSTROM K ET AL. 2004.MALMSTROM K ET AL. 2004. ETORICOXIB IN ACUTE PAIN ASSOCIATED WITH DENTAL SURGERY: A RANDOMIZED, DOUBLE-BLIND, PLACEBO- AND ACTIVE COMPARATOR-CONTROLLED DOSE-RANGING STUDY. 26(5):667-679 • PAEDIATRIC ANALGESIA GUIDELINES. JUNE 2017. ROYAL CORNWALLPAEDIATRIC ANALGESIA GUIDELINES. JUNE 2017. ROYAL CORNWALL HOSPITALSHOSPITALS