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   Closed circulatory system Chambered Valved
 Fish: -two chambered -oxygenated and deoxygenated blood - one way circulation
 Reptiles: -three chambered -oxygenated and deoxygenated blood -two atrium and one ventricle
Human -four chambered -no blood mixed - Valve -muscular -two direction blood flow 
  Red blood cell Carry oxygen

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Heart