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One-linerPharmacology
RECALLSforNEETPG
2022
Toexcelinyourupcomingexam,it'simportanttomasterpharmacology.
Understandingkeyconceptsandmechanismsofaction,indications,adverse
effects,andtoxicitiesforeachdrugiskeytoyoursuccess.
Dr.ShivankanKakkar,MD
HereisaTOPICWISEcuratedlistofone-
linersfrompharmacologyMCQsthat
werefeaturedintheNEETPG2022
exam.
Pharmacological
MechanismsandDrug
Effects
1 BotulinumToxin
Overdose
Botulinumtoxinblocks
acetylcholinerelease,causing
muscleparalysis.
2 PCSK9Inhibitor
EvolocumabinhibitsPCSK9,
aproteinthatregulates
cholesterollevels.
3 Parkinson'sDisease
Treatment
Selegilineisaselective
inhibitorofMAO-B,leadingto
increaseddopaminelevels
andimprovedsymptoms.
4 MDRTBResistance
Isoniazidandrifampicinare
lesseffectiveduetomulti-
drugresistantstrainsofTB.
5 Anti-microbialAdverseEffectinPregnancy
Fluoroquinolonescancausetendonruptureandarthropathyinababy
ofapregnantfemalewithUTI.
Toxicology
1 Acetaminophen
OverdoseTreatment
N-acetylcysteine
replenishesglutathione,
protectinglivercellsfrom
damage.
2 DigoxinToxicity
Management
DIGIBINDisanantibody
fragmentthatinactivates
digoxinincasesof
toxicity.
3 OpioidPoisoning
Management
Naloxoneisacompetitive
antagonistthatreverses
respiratorydepression
causedbyopioid
overdose.
EndocrinePharmacology
1 PituitaryTumorTreatment
Octreotideinhibitsgrowthhormonerelease
fromthepituitarygland.
2 AcromegalySymptomsTreatment
Pegvisomantblockstheactionofgrowth
hormone,improvingsymptomsin
acromegaly.
3 HyperprolactinemiaTreatment
Bromocriptineinhibitsprolactinsecretion,
treatinghyperprolactinemiaandassociated
symptoms.
4 DiabeticEmergencyManagement
Indiabeticketoacidosis(DKA),insulinand
fluidsaregiventorestoreelectrolytebalance
andcorrecttheacidosis.
CVSPharmacology
1 PulmonaryEdema
Management
IVnitroglycerineisusedto
manageacutepulmonary
edemaduetouncontrolled
hypertension.
2 Hyperkalemia
Treatment
Epinephrineisusedto
decreaseextracellular
potassiumlevelsinpatients
withhyperkalemia.
CNSPharmacology
MigraineTreatment
Sumatriptanisaselectiveserotoninreceptoragonistusedinthe
treatmentofacutemigraineattacks.
Anti-TBDrugs
Isoniazidcancauseperipheralneuropathyasanadverseeffect.Patients
takingisoniazidmayrequirevitaminB6supplementationtoprevent
neuropathy.
AdverseEffects
1 PurpleToeSyndrome
Warfarinhasbeenimplicated
inthedevelopmentofpurple
toesyndrome.
2 DystoniainOvarian
CancerPatients
Metoclopramidecancause
dystonia,particularlyin
patientsreceivinghigh-dose
cisplatintherapy.

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