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Scientific method
Lecture #1, Chapter 1
by John Cozza, Biology Dept.
(some material modified from Raven, Biology 9th
ed.)
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Science of Biology outline
• How to succeed
• What is life?
• Levels of organization
• Brief history of life
• Scientific method
• Examples of inquiry
– Evolution
– Climate change
Science of Biology outline
• How to succeed
• What is life?
• Levels of organization
• Brief history of life
• Scientific method
• Examples of inquiry
– Evolution
– Climate change
Goals of General Biology 1
Describe & discuss
•Cell components and
how they function
•Inheritance on the
molecular, organismal,
and population levels
•Mechanisms of and
evidence for evolution
•Relevant applications
Study plan
1) Read relevant chapter(s)
– Summaries, figures
– Review questions
1) Participate in lecture
– Interaction
– Notes
1) Review lecture ASAP
– Book
– Study group
1) Ask Qs & use office hours
Integrate!
• Lecture
• Book
• Lab
• PLTL
• Experiences &
resources
Science of Biology outline
• How to succeed
• What is life?
• Levels of organization
• Brief history of life
• Scientific method
• Examples of inquiry
– Evolution
– Climate change
Think—pair—share:
What is life?
NASA Curiosity rover on Mars
What is life?
• Movement
• Organization
• Compartmentalization
• Growth & reproduction
• Heredity
• Evolution
• Metabolism
• Interact with environment
• Homeostasis
• Entropy?
• Emergent properties http://environment.nationalgeographic.com/en
vironment/natural-disasters/hurricane-profile/
http://www.erh.noaa.gov/okx/okxfirewx.html
Define life?
Life is a
“self-sustaining
chemical system
capable of
Darwinian
evolution.”
- G.F. Joyce,
adopted as the
NASA definition Bains, W. 2004. Many chemistries could be
used to build living systems. Astrobiology
Think—pair—share:
Evidence for life on Earth?
NASA Galileo spacecraft
http://solarsystem.nasa.gov/multimedia/
display.cfm?IM_ID=462
Earth from Galileo spacecraft.
Closest approach 960 Km
Evidence for life on Earth?
• Abundant H2O
• Abundant O2
• Disequilibrium of CH4
• Absorption of red;
reflectance of green
• Radio wave emissions
Earth from Galileo spacecraft
Sagan, C. et al. 1993. A search for life
on Earth from the Galileo spacecraft.
Nature 365: 715-721
Science of Biology outline
• How to succeed
• What is life?
• Levels of organization
• Brief history of life
• Scientific method
• Examples of inquiry
– Evolution
– Climate change
Atoms to cell
Atoms to cell
Macromolecular
assembly
Cell to organism
Organisms to biosphere
?
Science of Biology outline
• How to succeed
• What is life?
• Levels of organization
• Brief history of life
• Scientific method
• Examples of inquiry
– Evolution
– Climate change
Key questions
• How did life begin?
• What were the major
innovations?
• Which were likely vs.
unlikely?
Archean eon
By Martin Schuler
Timeline
of life
http://commons.wikimedia.org/wiki/File:Timeline_evolution_of_life.svg
Timeline of life
L
L
U
U
Science of Biology outline
• How to succeed
• What is life?
• Levels of organization
• Brief history of life
• Scientific method
• Examples of inquiry
– Evolution
– Climate change
“Popperian” scientific method
observations
question
hypotheses
predictions experiments
hypotheses supported
or rejected
Karl Popper
1902-1994
http://en.wikipedia.or
g/wiki/Karl_Popper
“Popperian” scientific method
“Popperian” scientific method
observations
question
hypotheses
predictions experiments
hypotheses supported
or rejected
Science has many methods!
observations
question
hypotheses
predictions experiments
hypotheses supported
or rejected
correlations
model
description
theory
-big picture
-diverse support
Interactive question #1
A researcher is investigating the effect of
moderate wine consumption on
cardiovascular health. An example of a
prediction associated with the study
would be
A.Red wine is an antioxidant.
B.Red wine is popular in Italy, which has a
lower rate of heart attacks than the US.
C.Red wine slows atherosclerosis.
D.Red wine drinkers will have fewer heart
attacks than non-drinkers.
Scientific reasoning
Science
is a
social
process!
http://mistypedurl.com/2009/
03/bachelors-of-science/
Peer review
Science of Biology outline
• How to succeed
• What is life?
• Levels of organization
• Brief history of life
• Scientific method
• Examples of inquiry
– Evolution
– Climate change
Climate change: is it real?
http://www.skepticalscience.com/solar-activity-sunspots-global-warming-advanced.htm
Data from tree rings,
ice cores, sediments
Climate change: is it real?
http://climate.nasa.gov/key_indicators
http://www.worldviewofglobalwarming.org/pages/glaciers.php
http://climate.nasa.gov/key_indicators
Interactive question #2
Rising global
temperatures since
the late 1800s is an
example of a(n)
A.observation
B.hypothesis
C.model
D.correlation
E.experimental result
Atmospheric CO2
http://climate.nasa.gov/key_indicators
Atmospheric CO2
http://www.ethree.com/downloads/Climate%20Change%20Readings/Climate%20Science/History%20of%20Climate%20Science/xMaunaLoa.htm
Interactive question #3
“Temperature rise in the
20th
century was caused
by increased [CO2]” is an
example of a(n)
A.observation
B.hypothesis
C.model
D.correlation
E.experimental result
http://www.skepticalscience.com/co2-temperature-
Interactive question #4
The relationship of CO2
to temperature since
1970 is an example of
a(n)
A.observation
B.hypothesis
C.model
D.correlation
E.experimental result
Sea level rise
Projection of sea level rise from 1990 to 2100, based on three different
emissions scenarios. Also shown: observations of annual global sea
level rise over the past half century (red line), relative to 1990.
http://www.epa.gov/climatechange/science/future.html
Interactive question #5
Scenarios for sea level
rise by 2100 are an
example of a(n)
A.observation
B.hypothesis
C.model
D.correlation
E.experimental result
Science of Biology summary
• How to succeed
• What is life?
– Characteristics
– Levels of organization
– History
• Scientific method
Next:
• Biological molecules

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