1. MK318-SD-TUA5
T2* Mapping of Peroneal Tendons Using Clinically Relevant Subregions in an
Asymptomatic Population
Tuesday, Nov. 29 12:15PM - 12:45PM Room: MK Community, Learning Center Station #5
Participants
Katharine Wilson, MS, Vail, CO (Abstract Co-Author) Nothing to Disclose
Rachel K. Surowiec, MSc, Vail, CO (Abstract Co-Author) Nothing to Disclose
Nicholas S. Johnson, MD, Milwaukee, WI (Abstract Co-Author) Nothing to Disclose
Carly Lockard, MS, Vail, CO (Presenter) Nothing to Disclose
Thomas Clanton, MD, Vail, CO (Abstract Co-Author) Research funded, Siemens AG Research funded, Smith
& Nephew plc Research funded, Arthrex, Inc Research funded, Ossur
Charles P. Ho, MD, PhD, Vail, CO (Abstract Co-Author) Research funded, Siemens AG Research funded,
Smith & Nephew plc Research funded, Arthrex, Inc Research funded, Ossur HF Scientific Advisory Board,
Rotation Medical, Inc
PURPOSE
Quantify and analyze T2* mapping values in clinically relevant subregions of the peroneal brevis and
longus tendons in an asymptomatic cohort. This will provide baseline normative values for future
comparison with chronic and acute injuries of the tendon and will improve our understanding of the normal
variation of these biomarker values within the tendons.
METHOD AND MATERIALS
Unilateral ankle scans with T2* mapping were acquired of 26 asymptomatic subjects in the prone position
with a 3.0 T MRI system (axial plane, 2.5mm slice thickness, 0.54 x 0.54 mm in plane resolution, 4:47
acquisition time). The peroneal brevis and longus tendons were manually segmented and a bony landmark
was placed at the most inferior and lateral point of the lateral malleolus. Six subregions, each 1 cm in
length, were isolated along the length of the tendon including three subregions proximal to the lateral
malleolus and three subregions distal (Table 1). Summary statistics for T2* values in each subregion were
calculated as well as for the whole 6cm length of tendon (i.e. all subregions combined).
RESULTS
The peroneal brevis and longus tendons exhibited similar mean T2* values when the 6 cm length of
tendon was analyzed as a whole, with 10.28 ± 2.37 ms (mean ± standard deviation) found in the brevis
tendon and 10.75 ± 2.08 ms in the longus tendon. However, a trend of higher T2* values in the distal
subregions was found. The distal subregions had significantly higher T2* values than the two most
proximal subregions (proximal 2 and 3) of both the brevis and longus tendons (p<0.05). The subregional
results are summarized in Table 1.
CONCLUSION
T2* mapping values were presented for the peroneal tendons with a focus on clinically relevant
subregions. Regions immediately distal to the tip of the lateral malleolus had significantly higher T2*
values than those proximal to the lateral malleolus. This study provides a quantitative methodology and a
normative baseline of T2* mapping values for comparison with clinically compromised peroneal tendon
patients (acute and chronic cases) in the future.
CLINICAL RELEVANCE/APPLICATION
Higher T2* values distal to the lateral malleolus could be clinically relevant to peroneal tendon tears that

2. often initiate near the lateral malleolus, 5th metatarsal, inferior retinaculum and cuboid.