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CHAPTER 1
Multiple Choice: Select the appropriate answer(s):
1. From the following list, select the items which are associated with the development of drugs.
a. flowers
b. water
c. glass
d. plants
e. genes
2. From the following list, select the items which are associated with drug names.
a. brand
b. generic
c. trade
d. chemical
3. In which of the following pregnancy categories is systemic tetracycline classified?
a. A
b. B
c. C
d. D
e. X
4. Which of the following terms is defined as “an effect that is noxious and unintended, and that
occurs at doses used in man for prophylaxis, diagnosis, or therapy”?
a. toxic reaction
b. adverse drug reaction
c. adverse drug event
d. idiosyncratic reaction
5. Which of the following adverse effects is evident with antihistamines?
a. diarrhea
b. xerostomia
c. sedation
c. increased salivation
d. increased urination
6. Acetaminophen is a:
a. generic name
b. chemical name
c. trade name
d. brand name
7. Which of the following is an undesirable effect produced by a drug that has a predicatable
response and is dose related?
a. therapeutic effect
b. adverse effect
c. teratogenic effect
d. idiosyncratic reaction
8. Any type of adverse drug reaction should be reported to the
a. Food and Drug Administration (FDA).
b. Centers for Disease Control and Prevention (CDC).
c. Environmental Protection Agency (EPA).
d. Department of Human Resources.
Oral Pharmacology For The Dental Hygienist 2th Edition Weinberg Test Bank
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9. Prescription drugs are controlled by the
a. United States Food and Drug Administration (FDA).
b. Centers for Disease Control (CDC).
c. drug manufacturers.
d. local government.
10. Which of the following are goals of prescription writing?
a. To give an order for medications to be dispensed to the patient.
b. To communicate with the pharmacist to minimize errors in dispensing.
c. To comply with any rules governing prescribing that could affect the patient’s ability to
obtain the drug.
d. To have written logs for the number of prescriptions written in the United States.
11. Which of the following is (are) found in the body of a prescription?
a. date
b. telephone number of prescriber
c. address of prescriber
d. name of drug
e. dosage of the drug
12. From the list, select the items which are found in the heading of a prescription?
a. dosage of drug
b. age of the patient
c. name of drug
d Rx symbol
e. patient’s name
13. From the list, select the items which are found in the closing of a prescription.
a. date the prescription was written
b. number of allowable refills
c. directions to label the container
d. age of patient
e. name of patient
14. Which of the following terms is used to indicate that medical studies have shown that the drug
causes a significant risk of serious or even life-threatening adverse effects?
a. package insert
b. black box warning
c. DEA number
d. indications
15. From the following list, select the items associated with the metric system.
a. liter
b. gram
c. grain
d. scruple
e. milligram
f. drams
g. minim
16. Which of the following units is a measure in the apothecary system?
a. liter
b. grain
c. milligram
d. kilogram
17. From the following list, select the items associated with allowing for substitutions on a
prescription.
a. generic drugs are better than brand name drugs.
b. generic drugs are cheaper for the patient.
c. generic drugs are cheaper for the insurance company
d. generic drugs are more expensive.
e. generic drugs have less strength.
18. From the following list, select the items associated with how many times can a prescription for a
schedule III drug be refilled.
a. twice
b. three
c. four
d. five
e. six
f. eight
g. ten
19. From the following list, select the items associated with ways to avoid medication errors.
a. write clearly on the prescription.
b. call the pharmacist after writing the prescription.
c. make a copy of the prescription.
d. talk to the patient about the medication he or she will be taking.
e. write in ink.
f. avoid abbreviations.
20. The abbreviation “ac” means
a. before meals.
b. after meals.
c. at bedtime.
d. take with food.
21. Which part of the prescription is the signature of the prescriber?
a. heading
b. middle
c. body
d. closing
22. Which of the following ways may help reduce prescription errors?
a. Prescriptions should be written in pencil.
b. Electronic prescribing.
c. Prescriber should always use prescriptions with the drug name preprinted.
d. Telephone all prescriptions to the pharmacist.
23. According to the prescription, how many capsules are being prescribed?
License: 0111111
DEA # AW123445555
John David, DDS
1111 Main Street
New York , NY 11111
(212) 111-1234
Name Mary Smith Age ____56___
Address 1234 South St, NY Date 7/1/06
Amoxicillin 500 mg
Disp: # _____ caps.
Sig: Take two caps stat, followed by one cap tid for 7 days until finished for dental infection
____________________________
This prescription will be filled generically unless prescriber writes “daw” in the box below
label
a. 21
b. 22
c. 24
d. 25
24. Taking the “two caps stat” is considered to be a
a. loading dose.
b. maintenance dose.
c. toxic dose.
d. allergic dose.
25. Written on a prescription is “Sig: 1 qid pc and hs.” This is translated to mean
a. take one 3 times a day and at night.
b. take one 5 times a day and after meals.
c. take one 4 times a day after meals and at bedtime.
d. take one 4 times a day before meals and in the morning.
26. Which of the following is required to be on a prescription?
a. side effects of the medicine
b. drug interactions
c. telephone number of patient
d. age of the patient
e. date prescription was written
27. The abbreviation “prn” means
a. as needed.
b. take frequently.
c. as directed.
d. with meals.
28. If a prescriber signs the “substitution permissible” line, then the pharmacist
a. must use the cheaper generic drug.
b. can ask the patient if he/she prefers the generic or brand name drug.
c. must use the more expensive drug.
d. must use the brand name drug.
e. uses whatever drug is available.
True or False
________ 1. Another name for the trade name of a drug is proprietary name.
____ 2. Clarithromycin (Biaxin) is an antibiotic and has an “A” pregnancy category.
____ 3. The Harrison Narcotics Act of 1914 established the first drug abuse legislation in the United
States.
____ 4. Posology is the study of the dosages of medicines and drugs.
________ 5. The FDA stands for the Food and Drug Agency.
____ 6. Pharmacokinetics is the study of how the drug is handled by the body.
7. Tominimizemedicationerror,theprescriptionshouldbewritteninpencil.
____ 8. The metric system uses the old measures of weights.
____ 9. Drug dosages for infants are the same as for adults.
____10.OTC drugs require a prescription.
____ 11. Prescriptions for C-II narcotics cannot be refilled by the pharmacist.
____ 12. Federal laws allow the prescriber to prescribe a drug for an “off-labeled use.”
____ 13. A dentist can write a prescription for a drug for a heart condition.
____ 14. It is not necessary to write on a prescription the dose and dose frequency of the medication
because the patient knows what drug he or she is taking.
____ 15. Writing “take as directed” is correct and legal.
____ 16. 1 gm equals to 1000 mg.
Fill in the Blank
1. ____________________________are caused by drug induced damage to DNA (deoxyribonucleic acid) present in the male and
female gametes.
2. ______________is defined as harmful effects associated with drug overdose.
3. The ______________name for a drug is a registered trademark belonging to a particular drug manufacturer.
4. ______________refers to the unexplained responses of a drug.
5. Penicillin has a FDA pregnancy category of _______.
6. It is important to avoid complications to minimize medication ______________.
7. Drugs that have a high abuse potential are called ______________drugs.
8. DAW is an abbreviation for ____________________________.
9. The abbreviation of a gram is ______________.
10. The abbreviation of a milliliter is ______________.
11. The generic name of Vibramycin is ______________.
12. The abbreviation for “twice a day” is ______________.
13. The abbreviation for “three times a day” is ______________.
14. The abbreviation for “four times a day” is ______________.
15. The abbreviation for “immediately” is ______________
16.The abbreviation for “every hour” is ______________
17. The abbreviation “SIG” means __________________________________________.
18. The abbreviation “PO” means ______________.
19. Drug Enforcement Administration is abbreviated ______________.
20. The abbreviation “hs” indicates to take the medicine at ______________.
21. The abbreviation “qd” indicated to take the medicine ____________________________.
22. The date the prescription was written is contained in the ______________of the prescription.
23. The generic drug is usually ______________than the brand name.
24. “NR” on a prescription indicates ____________________________.
25. Tylenol with codeine #3, which is a C-III, may be refilled ______________times.
EXTENDED MATCHING
1. For each term listed below, select the correct definition from the list proveded.
Term Definition
1. Adverse effect a.more of a drug is needed to obtain the same effect
2. Idiosynrasy b. unexplained, uncharacteristic response to a drug
3. Tolerance c.drug-induced damage to the developing fetus
4. Teratogenic d. undesirble side effects that develop
.
2. For each drug schedule listed below, select the correct drug from the list provided
1. C-I a. oxycodone with acetaminophen (Percodan)
2. C-II b. acetaminophen (Tylenol) with codeine
3. C-III c. alprazolam (Xanax)
4. C-IV d. cough syrup with codeine
5. C-V e. heroin
f. hydrocodone with acetaminophen (Vicodin)
Case Study
A 65-year-old male patient presents to the dental office. His medical history revealed that he gets a
rash when he takes penicillin. The patient occasionally gets angina attacks for which he takes
nitroglycerin tablets. The patient takes ibuprofen daily. The patient is scheduled for a restorative
procedure and an oral prophylaxis. The pateint requires an antibiotic because of a endodontic
infection.
1. What information is related to the patient’s allergy to penicillin?
2. What are reference sources that can be used to look up medications the patient is taking?
3. What precautions should be taken while the patient is receiving dental treatment?
4. What are the different ways to determine if there are any drug interactions with the drugs the
patient is taking?
5. The patient asks you about what to expect in terms of good and bad effects of the drugs he is
taking. How do you explain this to the patient?
Case Study
1. What steps should be taken to reduce medication and prescription error in this case?
2. Label the parts of the prescription.
3. What would be the intended directions to the patient?
4. Explain the prescription to the patient.
5. The patient asked if there is a difference between the brand name and the generic form. What is
your reply?
License: 0111111
DEA # AW123445555
John David, DDS
1111 Main Street
New York , NY 11111
(212) 111-1234
Name Mary Smith Age ____A___
Address 1234 South St, NY Date 7/1/06
Hydrocodone/acetaminophen
Disp: # 10 tablets
Sig: Take as directed
____________________________
This prescription will be filled generically unless prescriber writes “daw” in the box below
Label
CHAPTER 2
Multiple Choice: Select the appropriate answer(s):
1.Which of the following routes of drug administration is used for the placement of Arestin
(minocycline)?
a. transdermal
b. topical
c. intramuscular
d. subcutaneous
2. Which of the following terms describes the actions of a tablet on the body after ingestion and
absorption?
a. pharmacology
b. pharmacokinetics
c. pharmacodynamics
d. toxicology
3. Which of the following terms describes the absorption of lidocaine local anesthetic after it is
injected into the tissues?
a. pharmacokinetics
b. pharmacodynamics
c. toxicology
d. adverse drug event
4. Which of the following dosage forms describes chlorhexidine gluconate oral rinse?
a. emulsion
b. solution
c. suppository
d. elixir
5. From the following list, select the items associated with enteral drug administration
a. oral
b. sublingual
c. intravenous
d. subcutaneous
e. rectal
d. transdermal
e. subgingival
f. inhalation
g. intramuscular
6. From the following list select the items associated with adverse drug reaction
a. noxious drug response
b. unintended response to a drug
c. reaction occurs to properly prescribed drug (normal dose or amount)
d. medical errors (miscalculation of dose)
e. confusion with name of drug prescribed (sounds similar to other drugs)
7. By which of the following routes of administration is insulin usually taken?
a. oral
b. subcutaneous
c. intramuscular
d. rectal
8. Which of the following routes of administration should a dental patient use for a nicotine patch?
a. oral
b. topical
c. transdermal
d. rectal
9.Nitroglycerin tablets are taken
a. sublingually.
b. transdermally.
c. topically.
d. intramuscularly.
10. Oraqix is a local anesthetic applied subgingivally. Which of the following routes of drug
administration is used to deliver the anesthetic?
a. topical
b. oral
c. transdermal
d. parenteral
11. Pharmacokinetics involves all of the following concepts?
a. absorption
b. distribution
c. metabolism
d. elimination
e. binding
12. Which of the following terms is used for metabolism?
a. biotransformation
b. excretion
c. liberation
d. elimination
13. Which of the following terms describes how much of a drug will be available in the body to
produce a pharmacologic response after it is administered?
a. bioequivalence
b. bioavailability
c. biotransformation
d. liberation
14. Absorption is bypassed if a drug is administered by which route?
a. topical
b. inhalation
c. intravenous
d. rectal
15. Which of the following drug characteristics will increase the tendency of a drug to cross cell
membranes?
a. ionized and high lipid solubility
b. nonionized and high lipid solubility
c. nonionized and low lipid solubility
d. ionized and low lipid solubility
16. How many half-lives does it take for a drug to be eliminated from the body?
a. 1–2
b. 2–3
c. 4–5
d. 5–6
17. Sublingual or buccal administered drugs must initially be able to go through the
a. epithelium of the oral mucosa (tongue or buccal mucosa).
b. connective tissue of the GI tract.
c. tissues of the stomach.
d. tissues of the nasopharynx.
18. Which of the following routes of drug absorption into the bloodstream is most common?
a. passive diffusion
b. active transport
c. facilitated diffusion
d. protein transport
19. All of the following alter the rate of absorption of drugs except one. Which one is the exception?
a. fatty foods
b. blood flow to the target organ
c. hydrogen ion concentration
d. surface area of the esophagus
20. Orally administered drugs must pass through the liver (via the hepatic portal vein) prior to
reaching general circulation and site of action. This is referred to as
a. enterohepatic circulation.
b. first-pass metabolism.
c. passive diffusion.
d. distribution.
21. Which of the following terms describes the movement of a drug once it is absorbed throughout
the body fluids to organs/tissues, which are the site of drug action?
a. absorption
b. liberation
c. distribution
d. elimination
22. Which route(s) of drug administration undergoes significant enterohepatic circulation?
a. oral
b. intravenous
c. intramuscular
d. subcutaneous
23. The primary site of drug biotransformation is the
a. gallbladder.
b. small intestine.
c. large intestine.
d. liver.
24. Which of the following enzymes found in the liver is primarily responsible for the
biotransformation of many dental drugs?
a. collagenase
b. cytochrome P450
c. hyaluronidase
d. elastase
25. The time it takes for the drug to eliminate 50% of the amount of its concentration in the plasma
or body is referred to as its
a. half-life.
b. excretion.
c. zero-order kinetics.
d. clearance.
26. The capacity of a body to eliminate a drug is referred to as
a. drug clearance.
b. half-life.
c. steady-state.
d. tubular reabsorption.
27. Which of the following terms describes the actions a drug has on the body?
a. pharmacokinetics
b. pharmacodynamics
c. pharmacology
d. toxicology
28. A drug that rapidly combines with a receptor to initiate a response and rapidly dissociates or
releases from the receptor is called a (an)
a. agonist.
b. antagonist.
c. receptor.
d. ligand.
29. Which of the following terms describes the drug dose that produces 50% of the maximum
possible response?
a. effective dose (ED50)
b. lethal dose
c. maximum response
d. half-life (t1⁄2)
30. Tachyphylaxis is a very rapid development of
a. tolerance.
b. adaptation.
c. mutation.
d. adjustment.
31. The term used to describe a decreased response to repeated administration of a drug is
a. drug dependence.
b. drug interaction.
c. tachyphylaxis.
d. tolerance.
32. Receptorsfordrugbindingareprimarilycomposedof
a. protein.
b. fat.
c. part of the drug.
d. cell membrane.
33. When a drug enters the blood, it may bind to molecules such as albumin, which makes the drug
inactive. This is termed
a. protein binding.
b. protein affinity.
c. drug action.
d. drug binding.
34. All of the following are disadvantages of orally administered drugs except one. Which one is the
exception?
a. undergoes first-pass effect
b. food interferes with absorption
c. cannot take if patient is vomiting
d. convenient form to administer
35. A maintenance dose of drug is given to
a. achieve an initial high drug concentration.
b. keep blood concentration in the therapeutic range.
c. allow the drug concentration to drop to 50% of its initial concentration.
d. achieve a maximal response.
True or False
- 1. After a drug is taken orally, it immediately passes into the bloodstream.
____ 2. Cell membranes are composed of three layers of fat.
____ 3. A drug that is soluble in fat is called hydrophilic.
____ 4. Passive diffusion of drugs across cell membranes/tissue barriers does not require energy.
____ 5. A lipophilic drug is more easily excreted in the urine.
____ 6. Weak acids such as aspirin are more readily absorbed from the stomach than weak bases.
____ 7. Drugs that are weak bases (e.g., erythromycin, codeine, and morphine) are more lipid
soluble and have greater absorption in the small intestine.
____ 8. Morphine has to be injected because it has a high first-pass metabolism.
____ 9. Polar drugs that are not metabolized are excreted unchanged in the urine.
____ 10. Drug dose is defined as the quantity of drug administered.
_ 11. A drug that is administered intravenously has 100% bioavailability.
- 12. Administration of lidocaine with epinephrine is by intramuscular injection.
- 13. Application of benzocaine 20% is topical.
- 14. Atridox is administered intramuscularly.
Fill in the Blank
1. Once a drug is orally administered into the body, it must be ______________into the bloodstream.
2. ______________refers to how much of a drug is absorbed into the blood after the dose is administered.
3. A drug that is intravenously injected has ______________percent bioavailability.
4. Anorallyadministereddrugisbetterabsorbedinthe____________________________thanthestomach.
5. Before a drug is absorbed into the blood, the drug must be absorbed through many ____________________________on its way
from the GI tract into the blood.
6. The barrier membrane between the blood and the tissue is called the ______________barrier.
7. During ______________diffusion the drug penetrates the membrane exclusively by diffusion, in which the rate of
transport is solely proportional to the concentration gradient.
8. Unlikeenteral-administereddrugs,______________administration of drugs bypasses the gastrointestinal tract.
9. The major barrier to absorption of topical administration of a drug is the top layer of skin called
the ____________________________.
10. A drug is eliminated either unchanged or as a ______________.
11. To be readily excreted in the urine a drug must be in a ______________soluble form.
12. A ______________is inactive when administered orally but becomes active after metabolism in the liver.
13. The enzymes in the liver are called ____________________________enzymes.
14. Most drugs undergo ____________________________of elimination.
15. The purpose of giving a ______________dose is to rapidly establish a therapeutic plasma drug concentration.
16. The site of drug attachment on the tissue is called the ______________.
17. A ______________response is the dose of drug that will give the greatest response, and increasing the dose will
not increase the response.
18. The ______________of a drug is the dose or amount of drug required to produce a particular or specific biologic
effect.
19. ______________is a homeostatic adjustment that may occur during a continued or prolonged presence of a drug.
20. A ______________is a treatment during research that is similar to the active medication except that it does not
contain the active drug.
21. ______________is the application of drugs to the skin that will be absorbed into the bloodstream.
22. An ______________injection is used when performing the tuberculin skin test for tuberculosis.
23. Oraqix is administered by the ______________route.
24. Arestin is applied in the ______ ________.
EXTENDED MATCHING
1.
For each route of drug administration listed below, select the correct drug that is
administered by that route of administration from the list provided
Route of drug administration Drug
1. transdermal a. dental anesthetic (e.g., lidocaine)
2. subcutaneous b. hepatitis B vaccine
3. intramuscular c. nicotine patch
4. topical d. Arestin or Atridox
e. insulin
f. benozcaine 20%
2.
For each term listed below, select the correct definition from the list provided
1. half-life a. rate and extent to which a drug is absorbed
2. affinity b. time taken for the blood concentration of a drug
to decrease 50% or one-half its concentration
3. bioavailability c. binding of a drug to a receptor
4. pharmacokinetics d. therapeutic response cannot be increased
with a higher dose of the drug
5. pharmacodynamics e. the effects of drugs on the body and
mechanisms of drug action
6. ceiling effect f. absorption of a drug
g. distribution of a drug through the blood
h. metabolism of a drug
Case Study
A 75-year-old male patient comes to the dental office for regular maintenance visits. The patient has
hypercholesterol levels and is taking simvastatin (Zocor). He presents to the office with an intraoral
swelling around the mandibular first molar region. A radiograph was taken and revealed a large
radiolucent area. Root canal treatment will have to be started. The patient is given a prescription for
penicillin V.
License: 0111111
DEA # AW123445555
John David, DDS
1111 Main Street
New York , NY 11111
(212) 111-1234
Name Mary Smith Age ____35___
Address 1234 South St, NY Date 7/1/06
Penicillin VK 500mg
Disp: # 29 tabs
Sig: Take two tablets orally at once, followed by one tablet four times a day.
____________________________
This prescription will be filled generically unless prescriber writes “daw” in the box below
label
1. Why is it important to ask this patient if he has any allergies?
2. Why is an initial dose of 1000 mg (2 tablets of 500 mg) given to the patient?
3. What should be reviewed before the prescription is given to the patient?
4. What pharmacokinetic factor should be considered when prescribing this antibiotic to the
patient?
5. When the patient swallows the tablet how does it reach the site of action? Also, what is the
intended site of action in this patient?
Chapter 3
Multiple Choice:Select the appropriate answer(s):
1. Drugs that act as mediators of sympathetic transmission (cause a sympathetic response) are
called
a. sympathomimetics.
b. parasympathetics.
c. cholinergics.
d. anticholinergics.
2. Drugs that decrease sympathetic activity are called
a. sympatholytics.
b. anticholinergics.
c. cholinergics.
d. adrenergics.
3. The two major types of receptors on or in the effectors (tissues) in the sympathetic or adrenergic
neuroeffector system are
a. nicotinic and muscarinic.
b.  (alpha) and ß (beta).
c. nicotinic and beta.
d. muscarinic and alpha.
4. Which of the following is true about the initial effects of an injection of epinephrine in local
anesthetics?
a. It increases systolic blood pressure.
b. It decreases systolic blood pressure.
c. It increases diastolic blood pressure.
d. It has no effect on blood pressure.
5. From the following list , select the items associated with epinephrine
a. increase systolic blood pressure.
b. increase cardiac output.
c. decrease heart rate.
d. decrease diastolic blood pressure
e. lower peripheral resistance
6. Which of the following organs/tissues has/have 1-receptors?
a. lung
b. liver
c. blood vessels
d. adrenal medulla
7. Which of the following organs/tissues has 2-receptors?
a. heart
b. lung
c. liver
d. presynaptic neurons
8. Which of the following organs/tissues has 1-receptors?
a. heart
b. lung
c. liver
d. kidney
9. From the following list, select the items associated with stimulation of the parasympathetic
division
a. xerotsomia.
b. saliva secretion.
c. increased heart rate.
d. urine retention.
e. tear secretion
f. urinary outflow
g. bronchiole constriction
10. A drug that stimulates 1-receptors is called a/an
a. sympathomimetic.
b. adrenergic agonist
c. adrenergic antagonist
d. sympatholytic.
e. cholinergic.
f. anticholinergic.
11. From the following list select the items associated with the actions of a drug that stimulates 1-
receptors
a. increased heart rate
b. decrease blood pressure
c. decrease heart contractility
d. increase heart contraction
e. increase heart conduction
d. no effect on the heart
12. Which of the following organs/tissues has/have ß2-receptors?
a. lung
b. heart
c. adrenal medulla
d. lacrimal (eye) gland
13. All of the following events occur with an 1-agonist except which one?
a. vasoconstriction of smooth muscle
b. nasal decongestant
c. increase blood pressure
d. vasodilation of skeletal muscle
14. Which of the following drugs is an 1-agonist?
a. clonidine
b. phenylephrine
c. aspirin
d. ibuprofen
15. The nervous system is divided into the
a. central and peripheral nervous system.
b. autonomic and peripheral nervous system.
c. sympathetic and parasympathetic nervous system.
d. central and autonomic nervous system.
16. In which of the following classifications do drugs for the management of attention-deficit
hyperactivity disorder (ADHD) belong?
a. direct-acting adrenergic agonists
b. indirect-acting adrenergic agonists
c. mixed-acting adrenergic agonists
d. cholinergic agonists
Oral Pharmacology For The Dental Hygienist 2th Edition Weinberg Test Bank
Full Download: https://testbanklive.com/download/oral-pharmacology-for-the-dental-hygienist-2th-edition-weinberg-test-bank/
Full download all chapters instantly please go to Solutions Manual, Test Bank site: TestBankLive.com

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Oral Pharmacology For The Dental Hygienist 2th Edition Weinberg Test Bank

  • 1. Test Bank CHAPTER 1 Multiple Choice: Select the appropriate answer(s): 1. From the following list, select the items which are associated with the development of drugs. a. flowers b. water c. glass d. plants e. genes 2. From the following list, select the items which are associated with drug names. a. brand b. generic c. trade d. chemical 3. In which of the following pregnancy categories is systemic tetracycline classified? a. A b. B c. C d. D e. X 4. Which of the following terms is defined as “an effect that is noxious and unintended, and that occurs at doses used in man for prophylaxis, diagnosis, or therapy”? a. toxic reaction b. adverse drug reaction c. adverse drug event d. idiosyncratic reaction 5. Which of the following adverse effects is evident with antihistamines? a. diarrhea b. xerostomia c. sedation c. increased salivation d. increased urination 6. Acetaminophen is a: a. generic name b. chemical name c. trade name d. brand name 7. Which of the following is an undesirable effect produced by a drug that has a predicatable response and is dose related? a. therapeutic effect b. adverse effect c. teratogenic effect d. idiosyncratic reaction 8. Any type of adverse drug reaction should be reported to the a. Food and Drug Administration (FDA). b. Centers for Disease Control and Prevention (CDC). c. Environmental Protection Agency (EPA). d. Department of Human Resources. Oral Pharmacology For The Dental Hygienist 2th Edition Weinberg Test Bank Full Download: https://testbanklive.com/download/oral-pharmacology-for-the-dental-hygienist-2th-edition-weinberg-test-bank/ Full download all chapters instantly please go to Solutions Manual, Test Bank site: TestBankLive.com
  • 2. 9. Prescription drugs are controlled by the a. United States Food and Drug Administration (FDA). b. Centers for Disease Control (CDC). c. drug manufacturers. d. local government. 10. Which of the following are goals of prescription writing? a. To give an order for medications to be dispensed to the patient. b. To communicate with the pharmacist to minimize errors in dispensing. c. To comply with any rules governing prescribing that could affect the patient’s ability to obtain the drug. d. To have written logs for the number of prescriptions written in the United States. 11. Which of the following is (are) found in the body of a prescription? a. date b. telephone number of prescriber c. address of prescriber d. name of drug e. dosage of the drug 12. From the list, select the items which are found in the heading of a prescription? a. dosage of drug b. age of the patient c. name of drug d Rx symbol e. patient’s name 13. From the list, select the items which are found in the closing of a prescription. a. date the prescription was written b. number of allowable refills c. directions to label the container d. age of patient e. name of patient 14. Which of the following terms is used to indicate that medical studies have shown that the drug causes a significant risk of serious or even life-threatening adverse effects? a. package insert b. black box warning c. DEA number d. indications 15. From the following list, select the items associated with the metric system. a. liter b. gram c. grain d. scruple e. milligram f. drams g. minim 16. Which of the following units is a measure in the apothecary system? a. liter b. grain c. milligram d. kilogram 17. From the following list, select the items associated with allowing for substitutions on a prescription. a. generic drugs are better than brand name drugs. b. generic drugs are cheaper for the patient.
  • 3. c. generic drugs are cheaper for the insurance company d. generic drugs are more expensive. e. generic drugs have less strength. 18. From the following list, select the items associated with how many times can a prescription for a schedule III drug be refilled. a. twice b. three c. four d. five e. six f. eight g. ten 19. From the following list, select the items associated with ways to avoid medication errors. a. write clearly on the prescription. b. call the pharmacist after writing the prescription. c. make a copy of the prescription. d. talk to the patient about the medication he or she will be taking. e. write in ink. f. avoid abbreviations. 20. The abbreviation “ac” means a. before meals. b. after meals. c. at bedtime. d. take with food. 21. Which part of the prescription is the signature of the prescriber? a. heading b. middle c. body d. closing 22. Which of the following ways may help reduce prescription errors? a. Prescriptions should be written in pencil. b. Electronic prescribing. c. Prescriber should always use prescriptions with the drug name preprinted. d. Telephone all prescriptions to the pharmacist. 23. According to the prescription, how many capsules are being prescribed? License: 0111111 DEA # AW123445555 John David, DDS 1111 Main Street New York , NY 11111 (212) 111-1234 Name Mary Smith Age ____56___ Address 1234 South St, NY Date 7/1/06 Amoxicillin 500 mg Disp: # _____ caps. Sig: Take two caps stat, followed by one cap tid for 7 days until finished for dental infection ____________________________ This prescription will be filled generically unless prescriber writes “daw” in the box below
  • 4. label a. 21 b. 22 c. 24 d. 25 24. Taking the “two caps stat” is considered to be a a. loading dose. b. maintenance dose. c. toxic dose. d. allergic dose. 25. Written on a prescription is “Sig: 1 qid pc and hs.” This is translated to mean a. take one 3 times a day and at night. b. take one 5 times a day and after meals. c. take one 4 times a day after meals and at bedtime. d. take one 4 times a day before meals and in the morning. 26. Which of the following is required to be on a prescription? a. side effects of the medicine b. drug interactions c. telephone number of patient d. age of the patient e. date prescription was written 27. The abbreviation “prn” means a. as needed. b. take frequently. c. as directed. d. with meals. 28. If a prescriber signs the “substitution permissible” line, then the pharmacist a. must use the cheaper generic drug. b. can ask the patient if he/she prefers the generic or brand name drug. c. must use the more expensive drug. d. must use the brand name drug. e. uses whatever drug is available. True or False ________ 1. Another name for the trade name of a drug is proprietary name. ____ 2. Clarithromycin (Biaxin) is an antibiotic and has an “A” pregnancy category. ____ 3. The Harrison Narcotics Act of 1914 established the first drug abuse legislation in the United States. ____ 4. Posology is the study of the dosages of medicines and drugs. ________ 5. The FDA stands for the Food and Drug Agency. ____ 6. Pharmacokinetics is the study of how the drug is handled by the body. 7. Tominimizemedicationerror,theprescriptionshouldbewritteninpencil. ____ 8. The metric system uses the old measures of weights. ____ 9. Drug dosages for infants are the same as for adults. ____10.OTC drugs require a prescription. ____ 11. Prescriptions for C-II narcotics cannot be refilled by the pharmacist. ____ 12. Federal laws allow the prescriber to prescribe a drug for an “off-labeled use.” ____ 13. A dentist can write a prescription for a drug for a heart condition.
  • 5. ____ 14. It is not necessary to write on a prescription the dose and dose frequency of the medication because the patient knows what drug he or she is taking. ____ 15. Writing “take as directed” is correct and legal. ____ 16. 1 gm equals to 1000 mg. Fill in the Blank 1. ____________________________are caused by drug induced damage to DNA (deoxyribonucleic acid) present in the male and female gametes. 2. ______________is defined as harmful effects associated with drug overdose. 3. The ______________name for a drug is a registered trademark belonging to a particular drug manufacturer. 4. ______________refers to the unexplained responses of a drug. 5. Penicillin has a FDA pregnancy category of _______. 6. It is important to avoid complications to minimize medication ______________. 7. Drugs that have a high abuse potential are called ______________drugs. 8. DAW is an abbreviation for ____________________________. 9. The abbreviation of a gram is ______________. 10. The abbreviation of a milliliter is ______________. 11. The generic name of Vibramycin is ______________. 12. The abbreviation for “twice a day” is ______________. 13. The abbreviation for “three times a day” is ______________. 14. The abbreviation for “four times a day” is ______________. 15. The abbreviation for “immediately” is ______________ 16.The abbreviation for “every hour” is ______________ 17. The abbreviation “SIG” means __________________________________________. 18. The abbreviation “PO” means ______________. 19. Drug Enforcement Administration is abbreviated ______________. 20. The abbreviation “hs” indicates to take the medicine at ______________. 21. The abbreviation “qd” indicated to take the medicine ____________________________. 22. The date the prescription was written is contained in the ______________of the prescription. 23. The generic drug is usually ______________than the brand name. 24. “NR” on a prescription indicates ____________________________. 25. Tylenol with codeine #3, which is a C-III, may be refilled ______________times. EXTENDED MATCHING 1. For each term listed below, select the correct definition from the list proveded. Term Definition 1. Adverse effect a.more of a drug is needed to obtain the same effect 2. Idiosynrasy b. unexplained, uncharacteristic response to a drug 3. Tolerance c.drug-induced damage to the developing fetus 4. Teratogenic d. undesirble side effects that develop
  • 6. . 2. For each drug schedule listed below, select the correct drug from the list provided 1. C-I a. oxycodone with acetaminophen (Percodan) 2. C-II b. acetaminophen (Tylenol) with codeine 3. C-III c. alprazolam (Xanax) 4. C-IV d. cough syrup with codeine 5. C-V e. heroin f. hydrocodone with acetaminophen (Vicodin) Case Study A 65-year-old male patient presents to the dental office. His medical history revealed that he gets a rash when he takes penicillin. The patient occasionally gets angina attacks for which he takes nitroglycerin tablets. The patient takes ibuprofen daily. The patient is scheduled for a restorative procedure and an oral prophylaxis. The pateint requires an antibiotic because of a endodontic infection. 1. What information is related to the patient’s allergy to penicillin? 2. What are reference sources that can be used to look up medications the patient is taking? 3. What precautions should be taken while the patient is receiving dental treatment? 4. What are the different ways to determine if there are any drug interactions with the drugs the patient is taking? 5. The patient asks you about what to expect in terms of good and bad effects of the drugs he is taking. How do you explain this to the patient? Case Study 1. What steps should be taken to reduce medication and prescription error in this case? 2. Label the parts of the prescription. 3. What would be the intended directions to the patient? 4. Explain the prescription to the patient. 5. The patient asked if there is a difference between the brand name and the generic form. What is your reply? License: 0111111 DEA # AW123445555 John David, DDS 1111 Main Street New York , NY 11111 (212) 111-1234 Name Mary Smith Age ____A___ Address 1234 South St, NY Date 7/1/06 Hydrocodone/acetaminophen Disp: # 10 tablets
  • 7. Sig: Take as directed ____________________________ This prescription will be filled generically unless prescriber writes “daw” in the box below Label CHAPTER 2 Multiple Choice: Select the appropriate answer(s): 1.Which of the following routes of drug administration is used for the placement of Arestin (minocycline)? a. transdermal b. topical c. intramuscular d. subcutaneous 2. Which of the following terms describes the actions of a tablet on the body after ingestion and absorption? a. pharmacology b. pharmacokinetics c. pharmacodynamics d. toxicology 3. Which of the following terms describes the absorption of lidocaine local anesthetic after it is injected into the tissues? a. pharmacokinetics b. pharmacodynamics c. toxicology d. adverse drug event 4. Which of the following dosage forms describes chlorhexidine gluconate oral rinse? a. emulsion b. solution c. suppository d. elixir 5. From the following list, select the items associated with enteral drug administration a. oral b. sublingual c. intravenous d. subcutaneous e. rectal d. transdermal e. subgingival f. inhalation g. intramuscular 6. From the following list select the items associated with adverse drug reaction a. noxious drug response
  • 8. b. unintended response to a drug c. reaction occurs to properly prescribed drug (normal dose or amount) d. medical errors (miscalculation of dose) e. confusion with name of drug prescribed (sounds similar to other drugs) 7. By which of the following routes of administration is insulin usually taken? a. oral b. subcutaneous c. intramuscular d. rectal 8. Which of the following routes of administration should a dental patient use for a nicotine patch? a. oral b. topical c. transdermal d. rectal 9.Nitroglycerin tablets are taken a. sublingually. b. transdermally. c. topically. d. intramuscularly. 10. Oraqix is a local anesthetic applied subgingivally. Which of the following routes of drug administration is used to deliver the anesthetic? a. topical b. oral c. transdermal d. parenteral 11. Pharmacokinetics involves all of the following concepts? a. absorption b. distribution c. metabolism d. elimination e. binding 12. Which of the following terms is used for metabolism? a. biotransformation b. excretion c. liberation d. elimination 13. Which of the following terms describes how much of a drug will be available in the body to produce a pharmacologic response after it is administered? a. bioequivalence b. bioavailability c. biotransformation d. liberation 14. Absorption is bypassed if a drug is administered by which route? a. topical b. inhalation c. intravenous d. rectal 15. Which of the following drug characteristics will increase the tendency of a drug to cross cell membranes?
  • 9. a. ionized and high lipid solubility b. nonionized and high lipid solubility c. nonionized and low lipid solubility d. ionized and low lipid solubility 16. How many half-lives does it take for a drug to be eliminated from the body? a. 1–2 b. 2–3 c. 4–5 d. 5–6 17. Sublingual or buccal administered drugs must initially be able to go through the a. epithelium of the oral mucosa (tongue or buccal mucosa). b. connective tissue of the GI tract. c. tissues of the stomach. d. tissues of the nasopharynx. 18. Which of the following routes of drug absorption into the bloodstream is most common? a. passive diffusion b. active transport c. facilitated diffusion d. protein transport 19. All of the following alter the rate of absorption of drugs except one. Which one is the exception? a. fatty foods b. blood flow to the target organ c. hydrogen ion concentration d. surface area of the esophagus 20. Orally administered drugs must pass through the liver (via the hepatic portal vein) prior to reaching general circulation and site of action. This is referred to as a. enterohepatic circulation. b. first-pass metabolism. c. passive diffusion. d. distribution. 21. Which of the following terms describes the movement of a drug once it is absorbed throughout the body fluids to organs/tissues, which are the site of drug action? a. absorption b. liberation c. distribution d. elimination 22. Which route(s) of drug administration undergoes significant enterohepatic circulation? a. oral b. intravenous c. intramuscular d. subcutaneous 23. The primary site of drug biotransformation is the a. gallbladder. b. small intestine. c. large intestine. d. liver. 24. Which of the following enzymes found in the liver is primarily responsible for the biotransformation of many dental drugs? a. collagenase b. cytochrome P450 c. hyaluronidase
  • 10. d. elastase 25. The time it takes for the drug to eliminate 50% of the amount of its concentration in the plasma or body is referred to as its a. half-life. b. excretion. c. zero-order kinetics. d. clearance. 26. The capacity of a body to eliminate a drug is referred to as a. drug clearance. b. half-life. c. steady-state. d. tubular reabsorption. 27. Which of the following terms describes the actions a drug has on the body? a. pharmacokinetics b. pharmacodynamics c. pharmacology d. toxicology 28. A drug that rapidly combines with a receptor to initiate a response and rapidly dissociates or releases from the receptor is called a (an) a. agonist. b. antagonist. c. receptor. d. ligand. 29. Which of the following terms describes the drug dose that produces 50% of the maximum possible response? a. effective dose (ED50) b. lethal dose c. maximum response d. half-life (t1⁄2) 30. Tachyphylaxis is a very rapid development of a. tolerance. b. adaptation. c. mutation. d. adjustment. 31. The term used to describe a decreased response to repeated administration of a drug is a. drug dependence. b. drug interaction. c. tachyphylaxis. d. tolerance. 32. Receptorsfordrugbindingareprimarilycomposedof a. protein. b. fat. c. part of the drug. d. cell membrane. 33. When a drug enters the blood, it may bind to molecules such as albumin, which makes the drug inactive. This is termed a. protein binding. b. protein affinity. c. drug action. d. drug binding.
  • 11. 34. All of the following are disadvantages of orally administered drugs except one. Which one is the exception? a. undergoes first-pass effect b. food interferes with absorption c. cannot take if patient is vomiting d. convenient form to administer 35. A maintenance dose of drug is given to a. achieve an initial high drug concentration. b. keep blood concentration in the therapeutic range. c. allow the drug concentration to drop to 50% of its initial concentration. d. achieve a maximal response. True or False - 1. After a drug is taken orally, it immediately passes into the bloodstream. ____ 2. Cell membranes are composed of three layers of fat. ____ 3. A drug that is soluble in fat is called hydrophilic. ____ 4. Passive diffusion of drugs across cell membranes/tissue barriers does not require energy. ____ 5. A lipophilic drug is more easily excreted in the urine. ____ 6. Weak acids such as aspirin are more readily absorbed from the stomach than weak bases. ____ 7. Drugs that are weak bases (e.g., erythromycin, codeine, and morphine) are more lipid soluble and have greater absorption in the small intestine. ____ 8. Morphine has to be injected because it has a high first-pass metabolism. ____ 9. Polar drugs that are not metabolized are excreted unchanged in the urine. ____ 10. Drug dose is defined as the quantity of drug administered. _ 11. A drug that is administered intravenously has 100% bioavailability. - 12. Administration of lidocaine with epinephrine is by intramuscular injection. - 13. Application of benzocaine 20% is topical. - 14. Atridox is administered intramuscularly. Fill in the Blank 1. Once a drug is orally administered into the body, it must be ______________into the bloodstream. 2. ______________refers to how much of a drug is absorbed into the blood after the dose is administered. 3. A drug that is intravenously injected has ______________percent bioavailability. 4. Anorallyadministereddrugisbetterabsorbedinthe____________________________thanthestomach. 5. Before a drug is absorbed into the blood, the drug must be absorbed through many ____________________________on its way from the GI tract into the blood. 6. The barrier membrane between the blood and the tissue is called the ______________barrier. 7. During ______________diffusion the drug penetrates the membrane exclusively by diffusion, in which the rate of transport is solely proportional to the concentration gradient. 8. Unlikeenteral-administereddrugs,______________administration of drugs bypasses the gastrointestinal tract.
  • 12. 9. The major barrier to absorption of topical administration of a drug is the top layer of skin called the ____________________________. 10. A drug is eliminated either unchanged or as a ______________. 11. To be readily excreted in the urine a drug must be in a ______________soluble form. 12. A ______________is inactive when administered orally but becomes active after metabolism in the liver. 13. The enzymes in the liver are called ____________________________enzymes. 14. Most drugs undergo ____________________________of elimination. 15. The purpose of giving a ______________dose is to rapidly establish a therapeutic plasma drug concentration. 16. The site of drug attachment on the tissue is called the ______________. 17. A ______________response is the dose of drug that will give the greatest response, and increasing the dose will not increase the response. 18. The ______________of a drug is the dose or amount of drug required to produce a particular or specific biologic effect. 19. ______________is a homeostatic adjustment that may occur during a continued or prolonged presence of a drug. 20. A ______________is a treatment during research that is similar to the active medication except that it does not contain the active drug. 21. ______________is the application of drugs to the skin that will be absorbed into the bloodstream. 22. An ______________injection is used when performing the tuberculin skin test for tuberculosis. 23. Oraqix is administered by the ______________route. 24. Arestin is applied in the ______ ________. EXTENDED MATCHING 1. For each route of drug administration listed below, select the correct drug that is administered by that route of administration from the list provided Route of drug administration Drug 1. transdermal a. dental anesthetic (e.g., lidocaine) 2. subcutaneous b. hepatitis B vaccine 3. intramuscular c. nicotine patch 4. topical d. Arestin or Atridox e. insulin f. benozcaine 20% 2. For each term listed below, select the correct definition from the list provided 1. half-life a. rate and extent to which a drug is absorbed 2. affinity b. time taken for the blood concentration of a drug to decrease 50% or one-half its concentration 3. bioavailability c. binding of a drug to a receptor 4. pharmacokinetics d. therapeutic response cannot be increased with a higher dose of the drug
  • 13. 5. pharmacodynamics e. the effects of drugs on the body and mechanisms of drug action 6. ceiling effect f. absorption of a drug g. distribution of a drug through the blood h. metabolism of a drug Case Study A 75-year-old male patient comes to the dental office for regular maintenance visits. The patient has hypercholesterol levels and is taking simvastatin (Zocor). He presents to the office with an intraoral swelling around the mandibular first molar region. A radiograph was taken and revealed a large radiolucent area. Root canal treatment will have to be started. The patient is given a prescription for penicillin V. License: 0111111 DEA # AW123445555 John David, DDS 1111 Main Street New York , NY 11111 (212) 111-1234 Name Mary Smith Age ____35___ Address 1234 South St, NY Date 7/1/06 Penicillin VK 500mg Disp: # 29 tabs Sig: Take two tablets orally at once, followed by one tablet four times a day. ____________________________ This prescription will be filled generically unless prescriber writes “daw” in the box below label 1. Why is it important to ask this patient if he has any allergies? 2. Why is an initial dose of 1000 mg (2 tablets of 500 mg) given to the patient? 3. What should be reviewed before the prescription is given to the patient? 4. What pharmacokinetic factor should be considered when prescribing this antibiotic to the patient? 5. When the patient swallows the tablet how does it reach the site of action? Also, what is the intended site of action in this patient?
  • 14. Chapter 3 Multiple Choice:Select the appropriate answer(s): 1. Drugs that act as mediators of sympathetic transmission (cause a sympathetic response) are called a. sympathomimetics. b. parasympathetics. c. cholinergics. d. anticholinergics. 2. Drugs that decrease sympathetic activity are called a. sympatholytics. b. anticholinergics. c. cholinergics. d. adrenergics. 3. The two major types of receptors on or in the effectors (tissues) in the sympathetic or adrenergic neuroeffector system are a. nicotinic and muscarinic. b.  (alpha) and ß (beta). c. nicotinic and beta. d. muscarinic and alpha. 4. Which of the following is true about the initial effects of an injection of epinephrine in local anesthetics? a. It increases systolic blood pressure. b. It decreases systolic blood pressure. c. It increases diastolic blood pressure. d. It has no effect on blood pressure. 5. From the following list , select the items associated with epinephrine a. increase systolic blood pressure. b. increase cardiac output. c. decrease heart rate. d. decrease diastolic blood pressure e. lower peripheral resistance 6. Which of the following organs/tissues has/have 1-receptors? a. lung b. liver c. blood vessels d. adrenal medulla 7. Which of the following organs/tissues has 2-receptors? a. heart b. lung c. liver d. presynaptic neurons 8. Which of the following organs/tissues has 1-receptors? a. heart b. lung c. liver d. kidney 9. From the following list, select the items associated with stimulation of the parasympathetic division
  • 15. a. xerotsomia. b. saliva secretion. c. increased heart rate. d. urine retention. e. tear secretion f. urinary outflow g. bronchiole constriction 10. A drug that stimulates 1-receptors is called a/an a. sympathomimetic. b. adrenergic agonist c. adrenergic antagonist d. sympatholytic. e. cholinergic. f. anticholinergic. 11. From the following list select the items associated with the actions of a drug that stimulates 1- receptors a. increased heart rate b. decrease blood pressure c. decrease heart contractility d. increase heart contraction e. increase heart conduction d. no effect on the heart 12. Which of the following organs/tissues has/have ß2-receptors? a. lung b. heart c. adrenal medulla d. lacrimal (eye) gland 13. All of the following events occur with an 1-agonist except which one? a. vasoconstriction of smooth muscle b. nasal decongestant c. increase blood pressure d. vasodilation of skeletal muscle 14. Which of the following drugs is an 1-agonist? a. clonidine b. phenylephrine c. aspirin d. ibuprofen 15. The nervous system is divided into the a. central and peripheral nervous system. b. autonomic and peripheral nervous system. c. sympathetic and parasympathetic nervous system. d. central and autonomic nervous system. 16. In which of the following classifications do drugs for the management of attention-deficit hyperactivity disorder (ADHD) belong? a. direct-acting adrenergic agonists b. indirect-acting adrenergic agonists c. mixed-acting adrenergic agonists d. cholinergic agonists Oral Pharmacology For The Dental Hygienist 2th Edition Weinberg Test Bank Full Download: https://testbanklive.com/download/oral-pharmacology-for-the-dental-hygienist-2th-edition-weinberg-test-bank/ Full download all chapters instantly please go to Solutions Manual, Test Bank site: TestBankLive.com