Antiepileptic drug phenytoin: uses, adverse effects and prodrug

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Antiepileptic drug-phenytoin uses,adverse effect, toxic effect,pro drug,fosphenytoin ,seizure

ANTIEPILEPTIC DRUH
•Phenytoin (Na channel
blocker)

PHOSPHENYTOIN-PRODRUG
•Water soluble prodrug
•Administration-IV/IM
•Use-Status epilepticus

AT TOXIC DOSES(ACUTE HIGH DOSE)
Cerebellar symptoms
*Ataxia
*Vertigo
*Nystagmus
*Diplopia

USES
*Generalised tonic-clonic seizure
*partial seizure
*Antiarrythmic drug
*Enhance wound healing
*Trigeminal neuralgia

ADVERSE EFFECTS •Gum hypertrophy
•Hirsutism
•Lymphadenopathy
•Teratogenic syndrome
•Megaloblastic anemia
•Hyperglycemia
•Osteomalecia/Rickets

Thank you

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Antiepileptic drug phenytoin: uses, adverse effects and prodrug

1. ANTIEPILEPTIC DRUH •Phenytoin (Na channel blocker)

2. PHOSPHENYTOIN-PRODRUG •Water soluble prodrug •Administration-IV/IM •Use-Status epilepticus

3. AT TOXIC DOSES(ACUTE HIGH DOSE) Cerebellar symptoms *Ataxia *Vertigo *Nystagmus *Diplopia

4. USES *Generalised tonic-clonic seizure *partial seizure *Antiarrythmic drug *Enhance wound healing *Trigeminal neuralgia

5. ADVERSE EFFECTS •Gum hypertrophy •Hirsutism •Lymphadenopathy •Teratogenic syndrome •Megaloblastic anemia •Hyperglycemia •Osteomalecia/Rickets