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Anna Krupa

New drugs development

Health & Medicine

The solubility improvement
as a tool to increase
the drug efficiency
Anna Krupa , PhD
Faculty of Pharmacy
Jagiellonian University Medical College

Poorly soluble drugs
80%
20%
New drugs
under
development

The aim: the best IVIVc
In vitro
results
In vivo
results

Why is it important?
Better
absorption
Higher
biodisponibility
Lower drug
dose
Lower risk of
side effects
Higher
efficacity of
the therapy
NEW
DRUGS !

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Antimicrobial Stewardship - the State Health Department Perspective - Dr. Marion A. Kainer, Director, Healthcare Associated Infections and Antimicrobial Resistance Program, Tennessee Department of Health, from the 2015 NIAA Antibiotic Symposium - Stewardship: From Metrics to Management, November 3-5, 2015, Atlanta, Georgia, USA. More presentations at http://swinecast.com/2015-niaa-symposium-antibiotics-stewardship-from-metrics-to-management

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This presentation is about how Google Docs may be used as an tool in data gathering and housing that functions as an intermediary database and is uploadable into multiple proprietary systems as well as being transferable between individuals or groups (ie. patient, clinic, primary car physician, social worker, etc.). The focus for this demonstration is using this tool to prevent harm and enhance care for patients who are either in chronic pain management programs or for cases of polypharmacy. The intended audience are nurses or other healthcare providers responsible for patient intake. There is a short case study and a link to a google form that you can experiment with. Please contact me if you have any difficulty accessing the Google form listed in the presentation.

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Companion Animal Antimicrobial Stewardship - Dr. Jeff Bender, Co-Director for the Upper Midwest Agricultural Safety and Health Center and Professor College of Veterinary Medicine and School of Public Health at the University of Minnesota, Chair for the AVMA Task Force for Antimicrobial Stewardship in companion Animal Practice, from the 2014 NIAA Symposium on Antibiotics Use and Resistance: Moving Forward Through Shared Stewardship, November 12-14, 2014, Atlanta, Georgia, USA. More presentations at http://www.swinecast.com/2014-niaa-antibiotics-moving-forward-through-shared-stewardship

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These are simplified slides discussing the regulation of cardiac output and venous return. Learning objectives: 1. Comprehend the determinants of cardiac output and factors affecting cardiac output 2. Comprehend the factors affecting stroke volume and heart rate and total peripheral resistance 3. Identify the factors regulating venous return 4. Discuss the causes of high and low output cardiac failure 5. Enlist the functions of veins and recognise the significance of venous reservoirs Study Resources: 1. Chapter 20, Guyton and Hall Textbook of Medical Physiology, 14th edition 2. Chapter 30 and 32, Ganong’s Review of Medical Physiology, 26th edition 3. Chapter 10, Human Physiology by Lauralee Sherwood, 9th edition 4. Physiology, Cardiac Output - StatPearls https://www.ncbi.nlm.nih.gov/books/NBK470455/

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