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Fractures and Bone
Healing
Response to Mechanical Stress
Wolff’s law – a bone grows or remodels in
response to the forces or demands placed
upon it
Observations supporting Wolff’s law include
 Long bones are thickest midway along the shaft
(where bending stress is greatest)
 Curved bones are thickest where they are most
likely to buckle
Response to Mechanical Stress
 Trabeculae form along lines of stress
 Large, bony projections occur where
heavy, active muscles attach
Response to Mechanical Stress
Statistics
Fractures of extremities most common
More common in men up to 45 years of age
More common in women over 45 years of age
Before 75 years wrist fractures (Colles’) most
common
After 75 years hip fractures most common
Fractures
A fracture is any break in a bone.
 Fracture repair involves formation of a clot called a
fracture hematoma, organization of the fracture
hematoma into granulation tissue called a procallus
(subsequently transformed into a fibrocartilaginous [soft]
callus), conversion of the fibrocartilaginous callus into
the spongy bone of a bony (hard) callus, and, finally,
remodeling of the callus to nearly original form.
6
Bone Fractures (Breaks)
Bone fractures are classified by:
The position of the bone ends after fracture
The completeness of the break
The orientation of the bone to the long axis
Whether or not the bones ends penetrate the skin
Common Types of Fractures
Magnitude and direction of force are determining
factors in type of fracture.
Closed
 – Bone fragments do not pierce skin
Open/compound
 – Bone fragments pierce skin
Displaced or undisplaced
Common Types of Fractures
Comminuted – bone fragments into three or
more pieces; common in the elderly
Spiral – ragged break when bone is excessively
twisted; common sports injury
Depressed – broken bone portion pressed
inward; typical skull fracture
Compression – bone is crushed; common in
porous bones
Common Types of Fractures
Epiphyseal – epiphysis separates from
diaphysis along epiphyseal line; occurs where
cartilage cells are dying
Greenstick – incomplete fracture where one
side of the bone breaks and the other side
bends; common in children
Common Types of Fractures
Common Types of Fractures
Common Types of Fractures
Common Types of Fractures
 Named for shape or position of fracture line
 Common types of fracture
 Pott’s -- distal fibular fracture
 Colles’s -- distal radial fracture
 stress fracture -- microscopic fissures from repeated strenuous
activities
14
Transverse fracture
Usually caused by directly applied force to
fracture site
Spiral (Oblique)
Caused by violence transmitted through limb
from a distance (twisting movements)
Greenstick
Occurs in children: bones soft and bend
without fracturing completely
Compression (Crush) fractures
Fracture in cancellous bone: result of
compression (osteoporosis)
Burst fracture
Occurs in short bones, e.g. vertebra from
strong direct pressure such as impaction of
disc.
Avulsion fracture
 Caused by traction, bony fragment usually torn off by a tendon or
ligament.
 What muscle group attaches to this bony prominence and what
nerve also runs in close proximity?
 Forearm flexors (common flexor origin) ulnar nerve
Fracture dislocation/subluxation
Fracture involves a joint: results in
malalignment of joint surfaces.
Impacted fracture
Bone fragments are impacted into each other.
Comminuated fracture
Two or more bone pieces - high energy
trauma
Comminuated fractures can require serious
hardware to repair.
Stress Fracture
 Abnormal stress on normal bone (fatigue
fracture) or normal stress on abnormal bone
(insufficiency fracture).
Functions of the X-ray
Localizes fracture and number of fragments
Indicates degree of displacement
Evidence of pre-existing disease in bone
Foreign bodies or air in tissues
May show other fractures
MRI, CT or ultrasound to reveal soft tissue damage
Repair/Healing of Bone
27
Healing is faster in bone than in cartilage due to lack
of blood vessels in cartilage
Healing of bone is still slow process due to vessel
damage
Clinical treatment
closed reduction = restore pieces to normal position by
manipulation
open reduction = realignment during surgery
How to Handle Fractures
 Reduction
 Open reduction
– Allows very accurate reduction
– Risk of infection
– Usually when internal fixation is needed
 Manipulation
– Usually with anesthesia
 Traction
– Fractures or dislocation requiring slow therapy
Fracture Fixation
4-12 weeks
External fixation
Internal fixation
 Intermedually nails, compression plates
Frame fixation
External fixation
Used for fractures that are too unstable for a
cast. You can shower and use the hand gently
with the external fixator in place.
Frame fixation
Allows correction of deformities by moving
the pins in relation to the frame.
Internal fixation
Repair of a
Fracture
33
Stages in the Healing of a Bone Fracture
Hematoma formation
Torn blood vessels
hemorrhage
A mass of clotted
blood (hematoma)
forms at the fracture
site
Site becomes swollen,
painful, and inflamed
3-4 hours 1
Hematoma
Hematoma formation
 The fibrocartilaginous callus forms when:
Osteoblasts and fibroblasts migrate to the fracture
and begin reconstructing the bone
Fibroblasts secrete collagen fibers that connect
broken bone ends
Osteoblasts begin forming spongy bone
Osteoblasts furthest from capillaries secrete an
externally bulging cartilaginous matrix that later
calcifies
 Fibrocartilaginous
callus forms
 Granulation tissue
(soft callus) forms
a few days after
the fracture
 Capillaries grow
into the tissue and
phagocytic cells
begin cleaning
debris
2 Fibrocartilaginous
callus formation
External
callus
New
blood
vessels
Spongy
bone
trabeculae
Internal
callus
(fibrous
tissue and
cartilage)
 Bony callus formation
New bone trabeculae appear
in the fibrocartilaginous callus
Fibrocartilaginous callus
converts into a bony (hard)
callus
Bone callus begins 3-4 weeks
after injury, and continues
until firm union is formed 2-3
months later 3 Bony callus
formation
Bony
callus of
spongy
bone
Bone remodeling
Excess material on
the bone shaft
exterior and in the
medullary canal is
removed
Compact bone is laid
down to reconstruct
shaft walls
4 Bone remodeling
Healing
fracture
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Fractures and Bone healing

  • 2. Response to Mechanical Stress Wolff’s law – a bone grows or remodels in response to the forces or demands placed upon it Observations supporting Wolff’s law include  Long bones are thickest midway along the shaft (where bending stress is greatest)  Curved bones are thickest where they are most likely to buckle
  • 3. Response to Mechanical Stress  Trabeculae form along lines of stress  Large, bony projections occur where heavy, active muscles attach
  • 5. Statistics Fractures of extremities most common More common in men up to 45 years of age More common in women over 45 years of age Before 75 years wrist fractures (Colles’) most common After 75 years hip fractures most common
  • 6. Fractures A fracture is any break in a bone.  Fracture repair involves formation of a clot called a fracture hematoma, organization of the fracture hematoma into granulation tissue called a procallus (subsequently transformed into a fibrocartilaginous [soft] callus), conversion of the fibrocartilaginous callus into the spongy bone of a bony (hard) callus, and, finally, remodeling of the callus to nearly original form. 6
  • 7. Bone Fractures (Breaks) Bone fractures are classified by: The position of the bone ends after fracture The completeness of the break The orientation of the bone to the long axis Whether or not the bones ends penetrate the skin
  • 8. Common Types of Fractures Magnitude and direction of force are determining factors in type of fracture. Closed  – Bone fragments do not pierce skin Open/compound  – Bone fragments pierce skin Displaced or undisplaced
  • 9. Common Types of Fractures Comminuted – bone fragments into three or more pieces; common in the elderly Spiral – ragged break when bone is excessively twisted; common sports injury Depressed – broken bone portion pressed inward; typical skull fracture Compression – bone is crushed; common in porous bones
  • 10. Common Types of Fractures Epiphyseal – epiphysis separates from diaphysis along epiphyseal line; occurs where cartilage cells are dying Greenstick – incomplete fracture where one side of the bone breaks and the other side bends; common in children
  • 11. Common Types of Fractures
  • 12. Common Types of Fractures
  • 13. Common Types of Fractures
  • 14. Common Types of Fractures  Named for shape or position of fracture line  Common types of fracture  Pott’s -- distal fibular fracture  Colles’s -- distal radial fracture  stress fracture -- microscopic fissures from repeated strenuous activities 14
  • 15. Transverse fracture Usually caused by directly applied force to fracture site
  • 16. Spiral (Oblique) Caused by violence transmitted through limb from a distance (twisting movements)
  • 17. Greenstick Occurs in children: bones soft and bend without fracturing completely
  • 18. Compression (Crush) fractures Fracture in cancellous bone: result of compression (osteoporosis)
  • 19. Burst fracture Occurs in short bones, e.g. vertebra from strong direct pressure such as impaction of disc.
  • 20. Avulsion fracture  Caused by traction, bony fragment usually torn off by a tendon or ligament.  What muscle group attaches to this bony prominence and what nerve also runs in close proximity?  Forearm flexors (common flexor origin) ulnar nerve
  • 21. Fracture dislocation/subluxation Fracture involves a joint: results in malalignment of joint surfaces.
  • 22. Impacted fracture Bone fragments are impacted into each other.
  • 23. Comminuated fracture Two or more bone pieces - high energy trauma
  • 24. Comminuated fractures can require serious hardware to repair.
  • 25. Stress Fracture  Abnormal stress on normal bone (fatigue fracture) or normal stress on abnormal bone (insufficiency fracture).
  • 26. Functions of the X-ray Localizes fracture and number of fragments Indicates degree of displacement Evidence of pre-existing disease in bone Foreign bodies or air in tissues May show other fractures MRI, CT or ultrasound to reveal soft tissue damage
  • 27. Repair/Healing of Bone 27 Healing is faster in bone than in cartilage due to lack of blood vessels in cartilage Healing of bone is still slow process due to vessel damage Clinical treatment closed reduction = restore pieces to normal position by manipulation open reduction = realignment during surgery
  • 28. How to Handle Fractures  Reduction  Open reduction – Allows very accurate reduction – Risk of infection – Usually when internal fixation is needed  Manipulation – Usually with anesthesia  Traction – Fractures or dislocation requiring slow therapy
  • 29. Fracture Fixation 4-12 weeks External fixation Internal fixation  Intermedually nails, compression plates Frame fixation
  • 30. External fixation Used for fractures that are too unstable for a cast. You can shower and use the hand gently with the external fixator in place.
  • 31. Frame fixation Allows correction of deformities by moving the pins in relation to the frame.
  • 34. Stages in the Healing of a Bone Fracture Hematoma formation Torn blood vessels hemorrhage A mass of clotted blood (hematoma) forms at the fracture site Site becomes swollen, painful, and inflamed 3-4 hours 1 Hematoma Hematoma formation
  • 35.  The fibrocartilaginous callus forms when: Osteoblasts and fibroblasts migrate to the fracture and begin reconstructing the bone Fibroblasts secrete collagen fibers that connect broken bone ends Osteoblasts begin forming spongy bone Osteoblasts furthest from capillaries secrete an externally bulging cartilaginous matrix that later calcifies
  • 36.  Fibrocartilaginous callus forms  Granulation tissue (soft callus) forms a few days after the fracture  Capillaries grow into the tissue and phagocytic cells begin cleaning debris 2 Fibrocartilaginous callus formation External callus New blood vessels Spongy bone trabeculae Internal callus (fibrous tissue and cartilage)
  • 37.  Bony callus formation New bone trabeculae appear in the fibrocartilaginous callus Fibrocartilaginous callus converts into a bony (hard) callus Bone callus begins 3-4 weeks after injury, and continues until firm union is formed 2-3 months later 3 Bony callus formation Bony callus of spongy bone
  • 38. Bone remodeling Excess material on the bone shaft exterior and in the medullary canal is removed Compact bone is laid down to reconstruct shaft walls 4 Bone remodeling Healing fracture