glucose transporters

1. Glucose Transporter
Glucose transporters are a wide group of membrane proteins that facilitate
the transport of glucose across the plasma membrane. Because glucose is a vital source
of energy for all life, these transporters are present in all phyla. The GLUT or SLC2A family
are a protein family that is found in most mammalian cells.
Glucose transporters Tissue Distribution Special properties
GLUT1 In mostly cells Help in basal glucose uptake
insulin independent
GLUT2 Liver, beta cells, hypothalamus,
and small intestine
Carrier for glucose and fructose
in liver and intestine
Insulin independent
GLUT3 Neurons, brain, placenta and
testes
Basal glucose uptake
Insulin independent
GLUT4 Cardiac muscle, fat, and skeletal
muscle
Activity increased by insulin
GLUT5 Kidney, sperm, and mucosal
surface of small intestine
Involve in fructose transport
Insulin independent