5. Discovered by Paul Langerhans in 1869
Group of cells that stand out from surrounding
cells
Cells inside islet include A,B,D,F & Epsilon
cells
6. Alpha cells produce glucagon
Beta cells produce insulin & amylin
Delta cells produce somatostatin
F/PP cells produce pancreatic polypeptide
Epsilon cells produce ghrelin
7. Type of Gland Location Cell Function Comments/Key points
Endocrine Islet periphery Alpha Glucagon production Glucagon is a hormone that increases the sugar in the blood
Endocrine Islet center Beta Insulin & amylin production Insulin decreases the sugar level in the blood & amylin gives humans a full feeling
Endocrine Inside islet or islet periphery Delta Somatostatin production Somatostatin is a growth inhibiting hormone
Endocrine Islet periphery PP (F) Pancreatic Polypeptide production Pancreatic polypeptide controls the activities of the pancreas
Endocrine Inside islet Epsilon Gherin production Gherin is a hormone that stimulates hungar
Exocrine Around exterior of pancreas Acini Digetive enzyme production and secretion Acini makes 99% of the pancreas
8. Pancreatitis
Pancreatic cancer
Diabetes Mellitus
9. Severe abdominal pain occurs suddenly
Can cause internal bleeding or shock
Excess alcohol ingestion & gallstones are
causes
Can give pancreas trauma
10. Also called pancreatic carcinoma
Common type are exocrine tumors
Endocrine tumors are usually malignant
11. Impact of amylin on weight control
Impact of somatostatin on ageing