“ Watch your thoughts; they become words. Watch your words; they become actions. Watch your actions; they become habits. Watch your habits; they become character. Watch your character; it becomes your destiny.” Frank Outlaw
Quick Pathology Review Shashidhar Venkatesh Murthy A/Prof.& Head of Pathology School of Medicine & Dentistry James Cook University Australia.
18y black man recurrent wheezing and difficulty breathing. markedly decreased FEV 1 , which improved significantly after he inhaled a few puffs of a β-adrenergic agonist . steroid inhalant was prescribed, which provided much greater relief. Four years later, he presented to the ED with severe shortness of breath of 8 hours' duration. O/E considerable distress ; he could barely talk, Resp rate 30/min. P/E rare wheezing and markedly diminished breath sounds. ABG pH 6.9, PCO 2 88 mm Hg, and PO 2 35 mm Hg . While awaiting therapy, Pt died following cardiac arrest. At autopsy, gross findings were limited to the respiratory tract. The lungs were overinflated, and had focal areas of atelectasis, and many of the bronchi were occluded by thick, tenacious, mucous plugs. ? Final diagnosis
Curschmann's spirals: whorls of shed epithelium within mucous plugs
Charcot-Leyden crystals: crystals within aggregates of eosinophils.
Thick mucous plug in lumen.
54y Male plumber presents with 3 year history of productive cough with yellowish green sputum. Occassionally blood stained. Sputum culture showed non specific mixed growth. Image shows his lung specimen. ? Diagnosis
Bronchopneumonia with abscesses.
Chronic fungal infection.
“ Happiness, satisfaction, and success in life depend on making the right choices, the winning choices. There are forces in life working for you and against you. One must distinguish the beneficial forces from the malevolent ones and choose correctly between them” - Wings of Fire : An Autobiography of Dr. APJ Abdul Kalam (1999)
“ It has been my personal experience that the true flavour, the real fun, the continuous excitement of work lie in the process of doing it rather than in having it over and done with. ” - Wings of Fire : An Autobiography of Dr. APJ Abdul Kalam (1999)