QPR-Oesophagus and stomach

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Quick Review of Pathology for clinicians and senior students.
Disorders of oesophagus and stomach.

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QPR-Oesophagus and stomach

  1. 1. “” - Wings of Fire: An Autobiography of Dr. APJ Abdul Kalam.<br />
  2. 2. Quick Pathology Review<br />Pathology of <br />Upper GIT<br />System : Gastro-Intestinal System<br />Class : Oesophagus & Stomach disorders<br />Topic : GERD, PUD & Other.<br />Shashidhar Venkatesh Murthy<br />A/Prof.& Head of Pathology<br />School of Medicine & Dentistry <br />James Cook University Australia.<br />
  3. 3. CPC 24- GIT-PUD: Core Learning Issues(CLI)<br />Major CLI:<br />GERD, Barrettsesophagus, Dysplasia & cancer.<br />Pathology of Peptic Ulcer Disease & its complications.<br />Minor CLI:<br />Oesophagitis – Acute / Chronic, Fungal.<br />Achalasia, Mallory Weiss syndrome, Hiatal hernia.<br />Oesophageal varices.<br />Acute & Chronic gastritis.<br />Zollinger Ellison syndrome (adenoma).<br />Pathology of oesophagus, Gastric & Duodenal Neoplasia.<br />GIST – Gastrointestinal stromaltumor.<br />
  4. 4. Cause of Hyperacidity ?<br />Cytokinase<br />Interleukins<br />Urease<br />Protease<br />Lipase<br />*H.pylori<br />
  5. 5. ?<br />Read – Dysphagia, Achalasia<br />Barrett’s oesophagus.<br />Adenocarcinoma oesophagus<br />Squamous carcinoma oesophagus<br />Stricture of oesophagus.<br />Diverticulum of oesophagus<br />
  6. 6. 52y male, presents with sudden circulatory failure & shock. Past history of heart burn on antacid therapy. Emergency gastrectomy done. Image shows his gastric wall.<br />What is the diagnosis? <br />* PUD Complications<br />PUD with adenocarcinoma.<br />Diffuse adenocarcinoma.<br />H.pylori chronic gastritis.<br />PUD with Perforation & Peritonitis<br />PUD with massive hemorrhage.<br />
  7. 7. ?<br />* Cirrhosis & Portal hypertension<br />Barrett’s oesophagus.<br />Adenocarcinoma oesophagus<br />Oesophageal varices<br />Stricture of oesophagus.<br />Diverticulum of oesophagus<br />
  8. 8. ?<br />* Oesophagus Carcinoma – Sq & Adeno<br />Barrett’s oesophagus.<br />Adenocarcinoma oesophagus<br />Oesophageal varices<br />Stricture of oesophagus.<br />Achalasia of oesophagus<br />
  9. 9. Alcoholic, 10y h/o dyspepsia, CT-Fluid & Air in peritoneal cavity <br />?<br />* PUD Complications<br />Cirrhosis<br />Cirrhosis with bleeding.<br />Gall stones & cholecystitis<br />Acute Intestinal obstruction.<br />Perforated peptic ulcer<br />
  10. 10. Diagnosis ?<br />* GERD<br />Barrett’s oesophagus.<br />Adenocarcinoma.<br />Squamous carcinoma.<br />Stricture of oesophagus.<br />Chronic Oesophagitis.<br />
  11. 11. Uniform clusters of cells separated by sinusoids -Adenoma  <br />?<br />* CushingsSy., Zollinger Ellison Sy<br />Gastrin.<br />Angiotensin.<br />Renin.<br />ACTH.<br />Insulin.<br />
  12. 12. “” - Wings of Fire: An Autobiography of Dr. APJ Abdul Kalam.<br />

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