role of diet in the management and prevention of endometriosis

1. The Role of Diet in the
Prevention and Manage
ment of Endometriosis
Presented by: Faiza Ibrahim-Audu
SPS/21/GND/00019
NUT7207:NUTRITION IN THE PREVENTION AND MANAGEMENT OF DISEASES
DR A.M. BELLO
BAYERO UNIVERSITY KANO - DEPARTMENT OF BIOCHEMISTRY

2. SYNOPSIS
INTRODUCTION
01
SYMPTOMS
02
PATHOPHYSIOLOGY
03
NUTRITION AND
ENDOMETRIOSIS
04
CONCUSION
REERENCES
05

3. 01
INTRODUCTION

4. Introduction
• Endometriosis is characterized by the presence of endometrial ti
ssues outside the uterine lining, typically on the external surface
of the uterus, the ovaries, fallopian tubes, abdominal wall, or int
estines.
• Endometriosis is a chronic condition that is usually developed se
veral years after menarche. It generally wanes after menopause.
• The treatment options and/or nutrition interventions are the sa
me for all age groups.
The role of nutrition in endometriosis is suggested by the influence
of diet on estrogenic activity and inflammatory processes.

5. 02
SYMPTOMS

6. Symptoms
• Common symptoms include:
• Severe pelvic pain
• Dysmenorrhea,
• Dyspareunia
• Fertility complications
• Fatigue, low back pain,
• Bloating, constipation, and
• Diarrhea.
Because symptoms may be non-specific, diagnosis is often delayed.

7. 03
PATHOPHYSIOLOGY

8. Pathophysiology
Various theories exist to explain the etiology of endometriosis
• A widely cited hypothesis is ovarian metaplasia via the
coelomic epithelium, leading to the formation of cysts or lesions
in theperitoneal cavity
• Also commonly accepted is the migration of endometrial
tissues outward through the fallopian tubes

9. 04
THE ROLE OF DIET IN THE PREVENTION
AND MANAGEMENT OF
ENDOMETRIOSIS

10. THE ROLE OF DIET IN THE PREVENTION AND
MANAGEMENT OF ENDOMETRIOSIS
Dietary factor Biological role in endometriosis
Animal products
Red meat, unprocessed Associated with an increased risk of edometriosis
Red meat, processed Associated with an increased risk of edometriosis
Dairy products) Contain estradiol and palmitic acid, associated with an incre
ased risk of endometriosis (27, 33
Dietary fat Increases circulating estrogen concentrations
Plant-based products
Dietary fiber Reduces circulating estrogen concentrations
Seaweed Estrogen-modulating activity
Polyphenols Anti-inflammatory
Vitamin D Anti-inflammatory activity

11. 05
DIETS USED TO MANAGE AND PREVENT
ENDOMETRIOSIS

12. DIETS USED TO MANAGE ENDOMETRIOSIS
Foods that can influence hormone regulation, particularly oestrogen balance, can ne
gatively affect those with endometriosis.
Foods to avoid or limit
Foods that may promote inflammation in the body and lead to further pain or progr
ession of the disorder. These foods include:
• alcohol
• caffeine
• gluten
• red meat
• saturated and tans fat

13. DIETS USED TO MANAGE ENDOMETRIOSIS
Anti-Inflammatory Diet
A typical anti-inflammatory diet focuses on eating more:
• fruits and vegetables,
• fatty fish like Sardines
• Nuts/ seeds and
• Healthy fats.
• Likewise, a reduction in alcohol, caffeine, dairy, refined sugar and
carbohydrates, red and processed meat, toxins (pesticides and
chemicals) and unhealthy fats.

14. DIETS USED TO MANAGE ENDOMETRIOSIS
FRUIT, ESPECIALLY BERRIES (Raspberries, blueberries, strawberries, peaches, oranges, pink grapefruit, red grapes, plums,
blackberries, cherries, apples and pears – to name a few) they’re packed with the antioxidant, anthocyanin’s (the com
pound that makes our food pretty colours), which is known to have anti-inflammatory effects. Aim for a variety in colo
ur to get a wide variety of nutrients.
VEGETABLES, ESPECIALLY CRUCIFEROUS and DARK LEAFY GREENS (spinach, kale, broccoli, cabbage, bok choy, cauliflower
, sprouts and washed raw salad greens – to name a few) these are loaded with the antioxidant, sulforaphane, this is k
nown to combat inflammation. Aim for a plate that is colourful to increase the variety of vitamins.
NUTS AND SEEDS (chai seeds, avocado, pecans, walnuts, almonds, ground flaxseed, and natural peanut butter) they’re fu
ll of healthy omega-3 fats. And omega-3 fats fight inflammation.
BEANS AND LEGUMES (Chickpeas, black-eyed peas, lentils, black beans, kidney beans, soybeans – to name a few) they fig
ht inflammation, and reduce cholesterol and stabilize blood sugar levels.
FISH AND SEAFOOD (Wild salmon, herring, sardines and black cod) Salmon is an excellent source of omega-3 fatty acids w
hich reduce inflammation. Eating sustainable, high quality salmon is important. Choose deep sea fish as they have a hi
gher intake of omega-3.
TEA, ESPECIALLY GREEN TEA, PEPPERMINT AND CHAMOMILE. Green tea contains the anti-inflammatory compound, EGG
C therefore it gets a lot of love, peppermint has been shown to have antioxidant properties and can help with digestio
n so is great post meal.
DARK CHOCOLATE it is packed with the antioxidant, flavanol known to reduce inflammation. The darker the chocolate the
better.
WHOLE GRAINS (gluten free noodles and pasta, brown rice, basmati rice, wild rice, buckwheat, quinoa, oats) Whole grain
s like oats, quinoa, and brown rice are high in fibre, which contain anti-inflammatory powers. The added fibre promot
es a healthy digestive tract and reduces spikes in blood sugar.
Foods to eat in Detail

15. DIETARY POLYPHENOLS IN EDOMETRIOSIS MANAGEMENT

16. SUMMARY AND CONCLUSION
• Because estrogens are key in the pathogenesis of endometriosis,
dietary factors that modulate estrogen activity may be clinically
important. Reducing dietary fat and increasing dietary fiber has been
shown to reduce circulating estrogen concentrations by roughly 10 to
25 percent. c
A diet rich in omega-3 fatty acids is associated with decreased inflammati
on and pain caused by endometriosis lesions
Polyphenols anti-inflammatory action and their potential
phytoestrogenic effect can modulate estrogen networks without
causing serious adverse effects unlike conventional anti-estrogenic
therapy

17. REFERENCES
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18. THANK YOU