The document discusses common causes of limitations in hand strength and dexterity due to aging and arthritis. It notes that hand weakness increases with age starting at age 50-59 and is more prevalent in women and those over 70. Arthritis, especially osteoarthritis and rheumatoid arthritis, are leading causes of hand disability. The document provides details on how these conditions affect different hand joints and grasps. It offers examples of design accommodations such as increasing contact areas to improve grip strength and alternatives to standard grips. Inspirational form concepts shown include orbs and stone shapes.