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Gap Acidosis

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Joel Topf
Joel Topf
Health & Medicine
1 of 32
Interesting Case Conference
THE CASE ,[object Object],[object Object],[object Object],[object Object]
THE CASE ,[object Object]
THE ANION GAP
THE ANION GAP ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
KETOACIDOSIS
KETOACIDOSIS
KETOACIDOSIS
KETOACIDOSIS
KETOACIDOSIS
LACTIC ACIDOSIS
LACTIC ACIDOSIS
Increased lactate production ,[object Object],[object Object],[object Object],[object Object]
Increased lactate production ,[object Object],[object Object],[object Object],[object Object]
Increased lactate production ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Increased lactate production ,[object Object],[object Object],[object Object],[object Object],[object Object]
Primary decrease in lactate utilization ,[object Object],[object Object],[object Object]
Mechanism uncertain ,[object Object],[object Object],[object Object],[object Object],[object Object]
UREMIA
TOXINS
TOXINS
Toxins Isopropanol is primarily metabolized via alcohol dehydrogenase to acetone
TOXINS
TOXINS
Clinical course in acute ethylene glycol intoxication ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical course in acute ethylene glycol intoxication 12 to 24 hours Cardiovascular Mild hypertension, tachycardia, and shock     Pulmonary Tachypnea adult respiratory distress syndrome pulmonary edema pneumonitis     Metabolic Metabolic acidosis with elevated anion gap decreased osmolal gap possible tetany from hypocalcemia, and hyperventilation
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TOXINS
TOXINS
TOXINS
TOXINS
Conclusion ,[object Object],[object Object],[object Object]

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