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EXCRETION FUN TIMES 
WITH MR. KIDNEY 
Claire Cheffey, Courtney Smith & 
Natalie Paige
What Is Excretion?
Excretion. (2014, January 1). Retrieved September 5, 2014, from 
http://www.thefreedictionary.com/excretion
1. Absorption 
2. Distribution 
3. 
Metabolism 
4. Excretion
Lehne, R (2013). Pharmokinetics. In Pharmacology for nursing care (8th ed., pp. 26- 
46). St. Louis, Mo.: Elsevier Saunders.
Steps in Renal Drug 
Excretion!!!!!!!
• Step #1: The kidney 
takes the drugs from the 
blood and puts them into 
the urine
• Step #2: Fat soluble 
drugs go back into the 
blood while others stay in 
the urine
• Step #3 : Those fat 
soluble drugs then enter 
back into the liver, and 
are then pumped from 
the blood into the 
kidneys and then into 
the urine 
Le, J. (2014, May 1). Drug Excretion. Retrieved September 5, 2014, from 
http://www.merckmanuals.com/professional/clinical_pharmacology/pharmacokinetics/drug_ 
excretion.html
• Step #4: The 
urine then 
travels through 
the ureters and 
bladder and out 
into the real 
world! 
Silverthorn, D.E. (2012). Human physiology: An integrated approach. 
Location: Publisher
So….. Why should nurses know 
this?
Excretion Fun Times with Mr. Kidney!
Excretion Fun Times with Mr. Kidney!
Excretion Fun Times with Mr. Kidney!
Excretion Fun Times with Mr. Kidney!

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Excretion Fun Times with Mr. Kidney!

  • 1. EXCRETION FUN TIMES WITH MR. KIDNEY Claire Cheffey, Courtney Smith & Natalie Paige
  • 3. Excretion. (2014, January 1). Retrieved September 5, 2014, from http://www.thefreedictionary.com/excretion
  • 4. 1. Absorption 2. Distribution 3. Metabolism 4. Excretion
  • 5. Lehne, R (2013). Pharmokinetics. In Pharmacology for nursing care (8th ed., pp. 26- 46). St. Louis, Mo.: Elsevier Saunders.
  • 6. Steps in Renal Drug Excretion!!!!!!!
  • 7. • Step #1: The kidney takes the drugs from the blood and puts them into the urine
  • 8. • Step #2: Fat soluble drugs go back into the blood while others stay in the urine
  • 9. • Step #3 : Those fat soluble drugs then enter back into the liver, and are then pumped from the blood into the kidneys and then into the urine Le, J. (2014, May 1). Drug Excretion. Retrieved September 5, 2014, from http://www.merckmanuals.com/professional/clinical_pharmacology/pharmacokinetics/drug_ excretion.html
  • 10. • Step #4: The urine then travels through the ureters and bladder and out into the real world! Silverthorn, D.E. (2012). Human physiology: An integrated approach. Location: Publisher
  • 11. So….. Why should nurses know this?

Editor's Notes

  1. Image site: http://fightingdarwin.blogspot.com/2009/01/doctor-demands-kidney-back.html
  2. -Excretion is defined as the removal of drugs from the body Excretion. (2014, January 1). Retrieved September 5, 2014, from http://www.thefreedictionary.com/excretion
  3. It is the last step in a drugs journey through the body- proceeded by absorption, distribution and metabolism
  4. Excretion occurs through- -the kidneys -the skin & sweat -saliva -through expired air -and bile with is stored in the gallbladder! But the renal excretion through the kidneys is the most important. Lehne, R (2013). Pharmokinetics. In Pharmacology for nursing care (8th ed., pp. 26-46). St. Louis, Mo.: Elsevier Saunders.
  5. Step #1: the kidney takes the drugs from the blood and into the urine
  6. Step #2: Fat soluble drugs go back into the blood while others stay in the urine
  7. #3: those fat soluble drugs then enter back into the liver, are metabolized, and then pumped from the blood into the kidneys and then into the urine Le, J. (2014, May 1). Drug Excretion. Retrieved September 5, 2014, from http://www.merckmanuals.com/professional/clinical_pharmacology/pharmacokinetics/drug_excretion.html
  8. The urine then travels through the ureters and the bladder and out into the real world! Silverthorn, D.E. (2012). Human physiology: An integrated approach. Location: Publisher
  9. Since the kidneys are a major part of drug excretion, the nurse needs to take into account the age of the patient and whether the kidneys are healthy or damaged. No one wants a sad, unhealthy kidney
  10. Age of patient- since kidneys of newborns are not fully developed, they wont be able to excrete drugs as well as adults. This should be accounted for when medicating an infant
  11. If the kidneys are damaged, like in renal failure patients, there may be increased drug response and toxicty. Oh no!
  12. As you can see and now understand, excretion and the kidneys play an important role in staying healthy & happy! Mr. Kidney is so excited you decided to stop by and hopes to see you again soon!