Practical radiological approach to a case of intersex

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Mohamed Shaaban

Health & Medicine

• Intersex
• DSD = Disorders of Sex Development

• Disorders of sex development (DSDs) are congenital
conditions in which the development of
chromosomal, gonadal, or anatomic sex is atypical.

• DSDs can be classified broadly into four categories on the basis of
gonadal histologic features:
1. Female pseudohermaphroditism (46,XX with two ovaries)
2. Male pseudohermaphroditism (46,XY with two testes)
3. True hermaphroditism (ovotesticular DSD) (both ovarian and testicular
tissues)
4. Gonadal dysgenesis, either mixed (a testis and a streak gonad) or pure
(bilateral streak gonads).

TDF (testis determining factor)
Testis
MIS (müllerian inhibiting substance)Testosterone
Müllerian duct
Wolffian duct

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the material discuss about a medical condition that has to deal with sexual development. in different stages of development, there is a need for gender identity and role, if there is a problem with any of these 2, there will be a problem with the sex assignment which will have an effect on the external genitalia sex. if all these pathway fall apart, there will be a condition called hermaphroditism which may be true or false. the material is exclusive on the topic

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