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8Breast Cancer Treatments on the Horizon
AccordingtotheJournaloftheNationalCancerInstitute,chemopreventionistheuseofpharmacologicornaturalagentsthatinhibitthedevelopmentofinvasivecancereitherbyblockingtheDNAdamagethatinitiatescancerformationorreversingtheprogressionofcellswherecancerhasalreadyformed.Drugsinthisarea,suchasFenretinide&aromataseinhibitors,arecurrentlybeingstudiedtoreducetheriskofbreastcancer.
Manywomenwithbreastcancerhavecellsthatmaybreakawayfromthetumorandenterthebloodstream.Thesecirculatingcellscannowbedetectedwithsensitivelabtesting.Thesetestscouldhelpdeterminewhichbreastcancerpatientsareatriskforremission.
Inscintimammography,ormolecularbreastimaging,aslightlyradioactivetracerisinjectedintothepatient’svein,andthetracerattachestobreastcancercells.Theroleofmolecularbreastimagingisstillbeingdetermined,butitmaybeusefulforfindingbreastcancersinthedensebreastsofyoungerwomen.
Forwomenatvariousstagesofbreastcancerwhoundergolumpectomyorpartialmastectomy,theprocedurecouldleadtobreastsofdifferentsizesandshapes;forwomenwithlargetumors,breastconservingsurgeriesmaynotevenbepossible.Surgeonsaresolvingtheseissueswithoncoplasticsurgery,inwhichtheyreshapethebreastatthetimeofinitialsurgeryandoperateontheotherbreasttomakethemmoresymmetrical.
PARPinhibitorstargetcancerscausedbyBRCAmutations,andtheyhavebeenfoundtobeeffectivewithtreatingbreast,ovarian,andprostatecancers.StudiesarenowbeingconductedtoseeifPARPinhibitorsarealsoeffectiveforcancersnotcausedbyBRCAmutations.
Anti-angiogenesis drugs 
Bloodvesselshavetogrowinordertonourishandpromotecancercellgrowth.Thisgrowthofbloodvesselsiscalledangiogenesis.Anti-angiogenesisdrugspreventtheformationofnewbloodvessels.Anti-angiogenesisdrugsarestillbeingstudiedtodeterminethepotentialeffectivenessintreatingadvancedbreastcancer.
Bisphosphonates 
Bisphosphonatescanhelpstrengthenbonesandreducebonefractureriskinbonesweakenedbymetastaticbreastcancer.Oneexampleiszoledronicacid,whichiscurrentlybeingstudiedforotherbenefitssuchasbreastcancerremission.
Vitamin D 
VitaminDdeficiencymaybelinkedtoapoorerdiagnosisforearlystagebreastcancerpatients. Moreresearchisneededontheireffectiveness,buttakingvitaminDsupplementsmaybehelpful.ItwouldbeagoodideatoaskyourdoctorifyourvitaminDlevelisinthehealthyrange.
1 in 8 women in the US will develop breast cancer in their lifetime, and for nearly 30% of them, the cancer will metastasize. 
Today, an estimated 150,000 to 250,000 women and men are living with metastatic breast cancerin the US. 
The average survival for a metastatic diagnosis is only 3 years. 
Stats of Interest
Medko is dedicated to helping North Americans find alternative breast cancer treatment options in Latin America. 
To learn more about our specialists’ treatment options, visit www.medkohealth.com

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