Critical care research

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Some considerations when undertaking research within the Critical Care Environment; presentation to students in the Graduate Diploma of Critical Care Nursing - University of Canberra

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  • Introduce self and role. Feel free to ask questions / interrupt, want to make it interactive. Who has participated in, or undertaken research? What do you know about research in the critical care environment? What do you think about research in the critical care environment?
  • Today I want to discuss a few topics relating to research in the critical care environment
  • All of these are quantitative in nature (meaning they use numbers). Qualitative is not included. Some studies are not suited to randomised control trials, eg: lived expereince
  • Efficacy - Insulin Safety – Activated protein C
  • What do we know about the population? How does it differ from doing research at a shopping centre? The patient population is: unwell, unable to make decision for themselves. So how do we obtain consent from an unwell, unconscious person. We don’t! does this mean we can enrol anyone into any research project? NHMRC
  • Don’t have time, The ‘So what’ questions: What will it do for me, What will it change Where to next? Come and discuss your ideas with us... Grad Dip Crit Care Build our own body of research and knowledge – we are not the same a medical, etc… People get scared by the term ‘research’. In generic terms this could mean, implementing best practice, undertaking QA, or doing research… where to start?
  • Critical care research

    1. 1. CRITICAL CARE RESEARCH Jamie Ranse Research Coordinator Intensive Care Unit The Canberra Hospital
    2. 2. OVERVIEW <ul><li>Levels of Evidence </li></ul><ul><li>Clinical Trials in Critical Care </li></ul><ul><li>Consent </li></ul><ul><li>Critical Care Nursing Research </li></ul><ul><li>Research and Evidence Based Practice Interest Group </li></ul>
    3. 3. LEVELS OF EVIDENCE <ul><li>I Systematic review of randomised controlled trials </li></ul><ul><li>II Randomised controlled trial </li></ul><ul><li>III Quasi-experimental </li></ul><ul><li>IV Case series, either post-test or pre-test and post-test </li></ul>
    4. 4. CLINICAL TRIALS IN CRITICAL CARE <ul><li>Systematic study of new drug therapy or medical intervention (normally randomised control trial) </li></ul><ul><li>To discover or verify: </li></ul><ul><ul><li>Pharmacodynamics (how it works) </li></ul></ul><ul><ul><li>Pharmacokinetics (what happens to it) </li></ul></ul><ul><ul><li>Therapeutic effects (efficacy) </li></ul></ul><ul><ul><li>Adverse reactions (safety) </li></ul></ul><ul><li>Form the basis of changing current medical practice </li></ul>
    5. 5. CLINICAL TRIALS IN CRITICAL CARE <ul><li>Drug or device development – progressive: </li></ul><ul><ul><li>Pre-clinical work including pharmacological and toxicological studies on animals </li></ul></ul><ul><ul><li>Satisfactory pre-clinical studies  drug or device proceeds to clinical trial </li></ul></ul><ul><ul><li>Successful clinical trial  marketing </li></ul></ul>
    6. 6. CONSENT <ul><li>What types of patients present to the critical care environment? </li></ul><ul><li>How do we obtain their consent to be involved in research? </li></ul>
    7. 7. CRITICAL CARE NURSING RESEARCH <ul><li>Why do nursing research? </li></ul><ul><li>How to do nursing research? </li></ul><ul><ul><li>Implementing best practice </li></ul></ul><ul><ul><li>Quality assurance </li></ul></ul><ul><ul><li>Research </li></ul></ul>
    8. 8. RESEARCH AND EVIDENCE BASED PRACTICE INTEREST GROUP <ul><li>To examine, explore and discuss research activities and evidence based practice within the critical care environment, particularly focusing on research and best practice evidence generated from within, and pertaining to, The Canberra Hospital Intensive Care Unit. </li></ul>
    9. 9. CRITICAL CARE RESEARCH Jamie Ranse Research Coordinator Intensive Care Unit The Canberra Hospital

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