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Critical care research

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Some considerations when undertaking research within the Critical Care Environment; presentation to students in the Graduate Diploma of Critical Care Nursing - University of Canberra

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Critical care research

  1. 1. CRITICAL CARE RESEARCH Jamie Ranse Research Coordinator Intensive Care Unit The Canberra Hospital
  2. 2. OVERVIEW <ul><li>Levels of Evidence </li></ul><ul><li>Clinical Trials in Critical Care </li></ul><ul><li>Consent </li></ul><ul><li>Critical Care Nursing Research </li></ul><ul><li>Research and Evidence Based Practice Interest Group </li></ul>
  3. 3. LEVELS OF EVIDENCE <ul><li>I Systematic review of randomised controlled trials </li></ul><ul><li>II Randomised controlled trial </li></ul><ul><li>III Quasi-experimental </li></ul><ul><li>IV Case series, either post-test or pre-test and post-test </li></ul>
  4. 4. CLINICAL TRIALS IN CRITICAL CARE <ul><li>Systematic study of new drug therapy or medical intervention (normally randomised control trial) </li></ul><ul><li>To discover or verify: </li></ul><ul><ul><li>Pharmacodynamics (how it works) </li></ul></ul><ul><ul><li>Pharmacokinetics (what happens to it) </li></ul></ul><ul><ul><li>Therapeutic effects (efficacy) </li></ul></ul><ul><ul><li>Adverse reactions (safety) </li></ul></ul><ul><li>Form the basis of changing current medical practice </li></ul>
  5. 5. CLINICAL TRIALS IN CRITICAL CARE <ul><li>Drug or device development – progressive: </li></ul><ul><ul><li>Pre-clinical work including pharmacological and toxicological studies on animals </li></ul></ul><ul><ul><li>Satisfactory pre-clinical studies  drug or device proceeds to clinical trial </li></ul></ul><ul><ul><li>Successful clinical trial  marketing </li></ul></ul>
  6. 6. CONSENT <ul><li>What types of patients present to the critical care environment? </li></ul><ul><li>How do we obtain their consent to be involved in research? </li></ul>
  7. 7. CRITICAL CARE NURSING RESEARCH <ul><li>Why do nursing research? </li></ul><ul><li>How to do nursing research? </li></ul><ul><ul><li>Implementing best practice </li></ul></ul><ul><ul><li>Quality assurance </li></ul></ul><ul><ul><li>Research </li></ul></ul>
  8. 8. RESEARCH AND EVIDENCE BASED PRACTICE INTEREST GROUP <ul><li>To examine, explore and discuss research activities and evidence based practice within the critical care environment, particularly focusing on research and best practice evidence generated from within, and pertaining to, The Canberra Hospital Intensive Care Unit. </li></ul>
  9. 9. CRITICAL CARE RESEARCH Jamie Ranse Research Coordinator Intensive Care Unit The Canberra Hospital

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