1. Lecture 3 : Studies of abnormal visual development

10. Number of Cells Ocular Dominance 0 10 20 30 40 50 60 70 80 1 2 3 4 5 6 7 RE closed for 9 days at birth: 4 years later there is little recovery

12. Number of Cells Ocular Dominance 0 10 20 30 40 50 60 70 80 1 2 3 4 5 6 7 RE closed at 7 days for 1 year then reversed for another year LE still dominates

15. Effect of reverse suture at 3 weeks of age on labelling pattern in the right cortex. Right eye sutured then opened and left eye sutured. Right eye was injected. RE dominated layer IVC  As layer was still plastic at 3 weeks. IVC  white as critical period was over (Le Vey et al., 1980)

16. Comparison of critical periods for direction selective and ocular dominance changes. Animals reared RE open movement right and then LE open movement left. Varied the age of the switch (Daw IOVS 1994).

31. Hirschberg technique

32. Corneal reflections central and symmetrical Rule: 1mm = 20∆ (approx. 11°)

33. 15deg 20/25deg 45deg Corneal reflections displaced temporally = esodeviation Corneal reflections displaced nasally = exodeviation