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Alzheimer’s disease and treatment
Eman youssif
Medical research institute2013
The content:
*structure of the brain
*risk factors
*mechanism of Alzheimer’s disease
*symptoms
*treatment
Hearing Words Speaking Words Seeing Words Thinking
structure
Hippocampus:
where short-term
memories are
converted to long-
term memories
Continue introduction
Proteins present normally in the brain
Risk factors
1-genetic factor
2- environmental
factor
3- age
4-life style
medication
smoking
Sleep deprivation
Depression and stress
Nutritional deficiency
Mechanism of Alzheimer’s disease
video
Accumulation of beta amyloid
TAU protein
Change of the brain
Affected regions begin to shrink as nerve cells die.
Symptoms of Alzheimer’s disease
Stage 1 (Mild) 2 to 4 years
depression
Less energetic Getting lost
Repetitive
questions and
conversations
Losing things or
misplacing them in
odd places
Noticeable
changes in
personality or
mood
Stage 2
Stage 2
(Moderate):
2 to 10 years
Forget recent
events and their
personal history
More disoriented
and disconnected
from reality
Speech problems
arise and
understanding
Reading and
writing are more
difficult
Stage 3
Stage 3 (Severe):
1 to 3 years during final
stage
lose the ability to feed
themselves, speak, recognize
people and control bodily
functions.
Their memory worsens and
may become almost non-
existent. They will sleep
often.
Stage 3 =memory loss
Treatment for stage 1
Stay calm and be
understanding.
Be patient and flexible. Don’t
argue or try to convince.
Acknowledge requests and
respond to them
Treatment for stage 1
Music therapy
In Alzheimer disruption of waves
so music can alter this disruption
So the result change the mood
treatment the first stage of Alzheimer
Treatment for stage 2
Color therapy
drugs
Donepezil ,rivastigmine and galantamine
Increase communication between the nerve cells
Temporarily improve or stabilize the symptoms of Alzheimer’s disease
Finally advise to you
Advise to you
references
Books:
1-Strategies for creating better care environment
Bib Alex
2-the encyclopedia of ALZ.. Disease –bib Alex
3-designing for Alzheimer’s disease-bib Alex
web site:
http://www.alz.org/aaic/overview.asp?gclid=CLyHlciwir0CFeFZ2wodAxUASA
http://www.alzheimers.org.uk/site/scripts/documents_info.php?documentID=147
http://www.mayoclinic.org/diseases-conditions/alzheimers-disease/basics/causes/con-20023871
http://www.nia.nih.gov/alzheimers/publication/alzheimers-disease-genetics-fact-sheet
http://www.nature.com/nrn/posters/ad/index.html
http://www.ncbi.nlm.nih.gov/pubmed/10653281
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013812
http://med.stanford.edu/news_releases/2007/july/music.html
http://www.health.harvard.edu/newsweek/Preventing_memory_loss.htm
Lectures::
Neurology lec. By prof .dr .Mohamed B. Abou – Donia –December 2013
Apoptosis course –medical research institute
Photo reference:
http://farm6.staticflickr.com/5286/5247137377_bb8a214e5f.jpg

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Alzheimer’s disease and treatment

Editor's Notes

  1. introduction
  2. Thalamus: receives sensory and limbic information and sends to cerebral cortexHypothalamus: monitors certain activities and controls body’s internal clockLimbic system: controls emotions and instinctive behavior (includes the hippocampus and parts of the cortex)Brain Stem – connects the spinal cord with the brainrelays and receives messages to and from muscles, skin, and other organscontrols automatic functions such as heart rate, blood pressure, and breathing
  3. الاصوات المختلفة لها ترددات مختلفة تخزن ف الذاكرة ف ناس بتفتكر الشخص عن طريق الصوت هو ازاى اصوات مختلفة بتحتفظ ف الذاكرة وبسترجعها زى صوت موسيقى صوت حد اعرفه
  4. الصوت لما بيدخل بيتحول الى نبضات كهربية
  5. Tau ................ الخلية عاملة زى الشجرةFunction of TAUStabilization and assembly of microtubuleVesicles transport
  6. وجدواااااا ان اول منطقة بيحصل فيها الميكانزم ده هى المنطقة الخاصة بالذاكرة
  7. Between 70 to 90% of people with AD eventually develop behavioral symptoms, including sleeplessness, anger, depression, and hallucinations
  8. بتدخل ع المناطق الاخرى
  9. كأنه بيبى لا يتذكر شيئااااااااااااااا
  10. اهم علاج التعامل النفسى مع المريض
  11. According to the American Music Therapy Association, “Music Therapy is the clinical and evidence-based use of music interventions to accomplish individualized goals within a therapeutic relationship by a credentialed professional who has completed an approved music therapy program.”Simply put, we use music to make your life better. Whether you need help socially, cognitively, physically, emotionally, or developmentally, music can help you get better…and music therapists are well-trained on how to do that.What’s more interesting, though, is why it works. When used properly, music can be an incredibly powerful treatment tool. And not just because it’s fun, relaxing, and motivating, but because music has a profound impact on our brains and our bodies
  12. Normalllllllllllllllllllly تجربةIf u turn on radio wave lenghheadphone and computer recorderu listen by 2 earsif u had a 400 HZ tone in one earif u had 404 HZ in the otheru wouid receive a third tone of 4 HZ
  13. الطبيعى الموجات دى موجودة بس عند مريض الزهايمر متلخبطة شوية وعشان كدة الموسيقى بتظبط المود
  14. The National Institute on Aging(NIA )is launching a new research partnership, called the Neuroimaging and Biomarkers of AD Initiative, to study how the brain changes in Mild Cognitive Impairment (MCI) and AD. Using MRIs conducted at regular intervals, researchers hope to learn precisely when and where in the brain problems occur. Researchers will also examine blood samples to check for higher levels of abnormal substances that could be considered “biomarkers” of AD.
  15. عين الجمل