It has been observed that fatty acid synthesis is impaired when this B vitamin is deficient. A lack of sufficient essential fatty acids results in impairment of brain and nerve tissue. The myelin sheath (the insulation around nerve cells) is malformed in a cobalamin deficiency and contributes to faulty nerve transmission. A prolonged B12 deficiency will ultimately lead to neurological disturbances.
2. DNA replication is dependent Backyard Healing Herbs Review on the function of coenzyme cobalamin as a methyl group
carrier. It is this role that explains why a deficiency of B-12 leads to megaloblastic anemia. This disorder is characterized
by large immature blood cells and changes in bone marrow. Inadequate DNA translation leading to improper cell
replication results in the large blood cells observed in this disorder. These large misshapen red blood cells are unable to
transport oxygen. This results in anemia leukopenia thrombopenia and fewer but larger and less mature blood cells. Poor
cell division in the gastrointestinal tract and epithelial tissues produces glossitis and megaloblastosis. Furthermore general
growth and repair are likewise impaired.
3. It has been observed that fatty acid synthesis is impaired
when this B vitamin is deficient. A lack of sufficient essential
fatty acids results in impairment of brain and nerve tissue.
The myelin sheath (the insulation around nerve cells) is
malformed in a cobalamin deficiency and contributes to
faulty nerve transmission. A prolonged B12 deficiency will
ultimately lead to neurological disturbances.
4. It has been recently acknowledged that excess homocysteine in the blood is the
cause of heart disease blood clots stroke and gangrene. Therefore the
understanding of this complementary action between B-12 and folic acid is a
significant addition to our arsenal of weapons for the fight against heart disease. It
is important to note that adequate amounts of both vitamin B12 and folic acid are
necessary for methionine synthesis to take place. You can say keeping
homocysteine levels low is a matter of life and death.
5. Cobalamin also provides important protection of the heart by way of its methyl transfer
role. It is active in the synthesis of the amino acid methionine from its precursor
homocysteine. The synthesis occurs by first removing a methyl group from methyl folate
a derivative of the biologically active form of folic acid. This methyl group is then
transferred to homocysteine and methionine is formed. Methionine is essential for
choline synthesis therefore vitamin B12 plays a secondary role in this lipid pathway. A
choline deficiency that causes fatty liver can be prevented by cobalamin or the other
methyl donors (betaine methionine folic acid).
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6. Cobalamin also provides important protection of the heart by way of its methyl transfer
role. It is active in the synthesis of the amino acid methionine from its precursor
homocysteine. The synthesis occurs by first removing a methyl group from methyl folate
a derivative of the biologically active form of folic acid. This methyl group is then
transferred to homocysteine and methionine is formed. Methionine is essential for
choline synthesis therefore vitamin B12 plays a secondary role in this lipid pathway. A
choline deficiency that causes fatty liver can be prevented by cobalamin or the other
methyl donors (betaine methionine folic acid).
https://neighboursreview.com/backyard-healing-herbs-reviews/