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THE FUTURE OF PHARMACY:
Using Technology to Drive Practice Change
Jerry Fahrni, Pharm.D.
Image source: Jerry Fahrni, Pharm.D. – All rights reserved
Literature supporting
“clinical pharmacy” is
plentiful
“...Develop and disseminate a futuristic practice
model that efficiently utilizes pharmacists as
direct patient care providers ...”
5 5
“I’m over here…”
“…uh, you should be here”
Pharmacy practice, especially practice
within the acute care setting, is largely
unchanged from what it was 30 years
ago. While it can be asserted that new
drugs have entered the market, more
pharmacists spend some or all of their
time in clinical practice, and, to some
degree, new technologies have become
available, too many pharmacists
continue to practice in the acute care
settings that provide roughly the same
services, using the same practice model
now, that they did in 1976....an obsolete
practice model.
“
Technology-enabled practice: A vision statement by the ASHP Section of Pharmacy Informatics and
Technology Am J Health Syst Pharm 2009 66: 1573-1577
"You know, like nunchuck skills, bo hunting skills, computer hacking skills. Girls
only like guys who have great skills." - Napoleon Dynamite
Medication Errors
Medication Errors That
Adversely Affect Patient
Care Outcomes
Net No. of Favorable
Outcomes Associated
with Each Variable
Pharmacist location
Decentralized ↓ ↓ 5
Centralized with ward visits ↑ ↑ -2
Centralized ↑ ↑ -2
Adopted from Table 4 - Clinical Pharmacy Services in U.S. Hospitals in 2020 Bond et al, Pharmacotherapy 2004
Traditional Storage IV Room
Refrigerated Storage Controlled Storage
Traditional Storage
Controlled Substances
Refrigerated Storage
I.V. Room / Cleanroom
2
3 4
Static shelving
Carousels
Inventory management systems
Medication trays/carts
Unit-dose packagers
Automated packagers
Robots
Bar code scanning
1
Traditional Storage
Controlled Substances
Refrigerated Storage
I.V. Room / Cleanroom
1
3 4
Static shelving (“non-controlled”)
Carousels (“non-controlled”)
Inventory management systems
Medication trays/carts
Unit-dose packagers
Automated packagers
Robots
Bar code scanning
2
Static shelving (refrigerated)
Carousels (refrigerated)
Inventory management systems
Bar code scanning
RFID technologies
Traditional Storage
Controlled Substances
Refrigerated Storage
I.V. Room / Cleanroom
1
4
Static shelving (“non-controlled”)
Carousels (“non-controlled”)
Inventory management systems
Medication trays/carts
Unit-dose packagers
Automated packagers
Robots
Bar code scanning
3
Static shelving (refrigerated)
Carousels (refrigerated)
Inventory management systems
Bar code scanning
RFID technologies
2
Static shelving
Carousels
Refrigerators
Inventory management systems
Bar code scanning
Traditional Storage
Controlled Substances
Refrigerated Storage
I.V. Room / Cleanroom
1
3
Static shelving (“non-controlled”)
Carousels (“non-controlled”)
Inventory management systems
Medication trays/carts
Unit-dose packagers
Automated packagers
Robots
Bar code scanning
4
Static shelving (refrigerated)
Carousels (refrigerated)
Inventory management systems
Bar code scanning
RFID technologies
2
Static shelving
Carousels (yes, really)
Refrigerators
Inventory management systems
Bar code scanning
Static shelving
Carousels
Refrigerators
Inventory management systems
Bar code scanning
IV workflow management systems
IV compounding robots
SAFETY
ELIMINATION OF
BIAS
REDUCE MULTI-
TASKING
IMPROVE DATA
COLLECTION
TRANSFORM THE
ROLE OF THE
TECHNICIAN
STANDARDIZE
WORKFLOW
CUT COST
IMPROVE
EFFICIENCY
Image source: Jerry Fahrni, Pharm.D. – All rights reserved
Optimizing Central Pharmacy Dispensing Technology. May 2016. PP&P:13(5)
SAFETY
ELIMINATION OF
BIAS
REDUCE MULTI-
TASKING
IMPROVE DATA
COLLECTION
TRANSFORM THE
ROLE OF THE
TECHNICIAN
STANDARDIZE
WORKFLOW
CUT COST
IMPROVE
EFFICIENCY
0% 10% 20% 30% 40% 50% 60% 70% 80% 90%
Medication Tracking Systems
Tray Management Systems
IV Workflow System
Waste Management
Automated Storage/Retrieval
Robots
Carousels
14%
15%
19%
33%
36%
38%
87%
Adapted from: State of Pharmacy
Automation. Pharm Purch Prod. 2016
Diffusion of Innovation
Sources: U.S. Bureau of the Census (1970 and various years); Cellular Telecommunications Industry Association (1996); The World Almanac and Book of Facts (1997) - http://www.glencoe.com/sec/socialstudies/economics/econtoday2001/pdfs/C22-02C-820489.pdf
Adoption of Smartpumps, BCMA, CPOE graphed as percent adoption over time (data source: AJHP - Vol 72 Jul 1, 2015)
Graph: Jerry Fahrni, Pharm.D. – All rights reserved
Have a clear, unambiguous advantage in either effectiveness or cost-effectiveness
Are compatible with the adopter’s values, norms, and perceived needs
Are perceived as simple to use
Knowledge to use innovation can be codified and transferred easily
When the technology can be refined and modified by the adopter to meet their specific needs
Carries a low degree of uncertainty, i.e. they are perceived as having little risk.
Observable benefits
It is relevant to the user’s work and improves task performance
Offer trialability - users can experiment on a limited basis
Technology offered as an “augmented product”
Greenhalgh, et al. The Milbank Quarterly, 82(4), 581–629.
THE FUTURE
Image source: Jerry Fahrni, Pharm.D. – All rights reserved
Augmented Reality
Pharmacogenomics
Sensors and mHealth
External sensors - blood-pressure cuffs and pulse oximeters
Wearables embedded in clothing or accessories
Epidermal sensors, such as patches and digital tattoos
Ingestibles embedded in pills that dissolve
Tissue-embedded sensors - pacemakers and defibrillators
Blood-sampling sensors, such as glucose meters
Subdermal Sensors
Nanotechnology
http://www.medgadget.com/2016/09/nanoparticles-made-building-blocks-integrate-multiple-chemo-agents.html
Selectively perforate bacterial cell membrane without affecting host cells
Release antibiotic in presence of infection
Target antibiotic to attack specific bacterial antigens
Gold coated nano shells heated up with light to destroy cancer cells
(Nanobullet)
Smart Insulin – “Glucose Sensitive Insulin”
Nano-artificial pancreas
Biodegradable nanoparticles that release growth factors and angiogenic
factors to improve bioengineering of heart or lung tissue
The first 3D-printed drug to win FDA approval
3D Printing
“It's like drinking from a fire hose”
~ Alfred Huger
PeterDiamandis
“
Professionals entrusted with the delivery and
administrations of pharmaceuticals have a
fundamental responsibility
to identify and implement interventions that will
improve patient quality outcome measures and also
reduce overall health-care costs. These interventions
include timely and judicious use of
therapeutic and technological advances
Meyer GE, et al. AJHP. 1991 May 1;48:953-966
“
THE FUTURE OF PHARMACY: Using Technology to Drive Practice Change
Jerry Fahrni, Pharm.D. || 559.838.6014 || @JFahrni

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The Future of Pharmacy: Using Technology to Drive Practice Change

  • 1. THE FUTURE OF PHARMACY: Using Technology to Drive Practice Change Jerry Fahrni, Pharm.D.
  • 2. Image source: Jerry Fahrni, Pharm.D. – All rights reserved
  • 4. “...Develop and disseminate a futuristic practice model that efficiently utilizes pharmacists as direct patient care providers ...”
  • 5. 5 5 “I’m over here…” “…uh, you should be here”
  • 6. Pharmacy practice, especially practice within the acute care setting, is largely unchanged from what it was 30 years ago. While it can be asserted that new drugs have entered the market, more pharmacists spend some or all of their time in clinical practice, and, to some degree, new technologies have become available, too many pharmacists continue to practice in the acute care settings that provide roughly the same services, using the same practice model now, that they did in 1976....an obsolete practice model. “ Technology-enabled practice: A vision statement by the ASHP Section of Pharmacy Informatics and Technology Am J Health Syst Pharm 2009 66: 1573-1577
  • 7. "You know, like nunchuck skills, bo hunting skills, computer hacking skills. Girls only like guys who have great skills." - Napoleon Dynamite
  • 8. Medication Errors Medication Errors That Adversely Affect Patient Care Outcomes Net No. of Favorable Outcomes Associated with Each Variable Pharmacist location Decentralized ↓ ↓ 5 Centralized with ward visits ↑ ↑ -2 Centralized ↑ ↑ -2 Adopted from Table 4 - Clinical Pharmacy Services in U.S. Hospitals in 2020 Bond et al, Pharmacotherapy 2004
  • 9. Traditional Storage IV Room Refrigerated Storage Controlled Storage
  • 10. Traditional Storage Controlled Substances Refrigerated Storage I.V. Room / Cleanroom 2 3 4 Static shelving Carousels Inventory management systems Medication trays/carts Unit-dose packagers Automated packagers Robots Bar code scanning 1
  • 11. Traditional Storage Controlled Substances Refrigerated Storage I.V. Room / Cleanroom 1 3 4 Static shelving (“non-controlled”) Carousels (“non-controlled”) Inventory management systems Medication trays/carts Unit-dose packagers Automated packagers Robots Bar code scanning 2 Static shelving (refrigerated) Carousels (refrigerated) Inventory management systems Bar code scanning RFID technologies
  • 12. Traditional Storage Controlled Substances Refrigerated Storage I.V. Room / Cleanroom 1 4 Static shelving (“non-controlled”) Carousels (“non-controlled”) Inventory management systems Medication trays/carts Unit-dose packagers Automated packagers Robots Bar code scanning 3 Static shelving (refrigerated) Carousels (refrigerated) Inventory management systems Bar code scanning RFID technologies 2 Static shelving Carousels Refrigerators Inventory management systems Bar code scanning
  • 13. Traditional Storage Controlled Substances Refrigerated Storage I.V. Room / Cleanroom 1 3 Static shelving (“non-controlled”) Carousels (“non-controlled”) Inventory management systems Medication trays/carts Unit-dose packagers Automated packagers Robots Bar code scanning 4 Static shelving (refrigerated) Carousels (refrigerated) Inventory management systems Bar code scanning RFID technologies 2 Static shelving Carousels (yes, really) Refrigerators Inventory management systems Bar code scanning Static shelving Carousels Refrigerators Inventory management systems Bar code scanning IV workflow management systems IV compounding robots
  • 14. SAFETY ELIMINATION OF BIAS REDUCE MULTI- TASKING IMPROVE DATA COLLECTION TRANSFORM THE ROLE OF THE TECHNICIAN STANDARDIZE WORKFLOW CUT COST IMPROVE EFFICIENCY Image source: Jerry Fahrni, Pharm.D. – All rights reserved
  • 15. Optimizing Central Pharmacy Dispensing Technology. May 2016. PP&P:13(5)
  • 16. SAFETY ELIMINATION OF BIAS REDUCE MULTI- TASKING IMPROVE DATA COLLECTION TRANSFORM THE ROLE OF THE TECHNICIAN STANDARDIZE WORKFLOW CUT COST IMPROVE EFFICIENCY
  • 17. 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% Medication Tracking Systems Tray Management Systems IV Workflow System Waste Management Automated Storage/Retrieval Robots Carousels 14% 15% 19% 33% 36% 38% 87% Adapted from: State of Pharmacy Automation. Pharm Purch Prod. 2016
  • 19. Sources: U.S. Bureau of the Census (1970 and various years); Cellular Telecommunications Industry Association (1996); The World Almanac and Book of Facts (1997) - http://www.glencoe.com/sec/socialstudies/economics/econtoday2001/pdfs/C22-02C-820489.pdf
  • 20. Adoption of Smartpumps, BCMA, CPOE graphed as percent adoption over time (data source: AJHP - Vol 72 Jul 1, 2015) Graph: Jerry Fahrni, Pharm.D. – All rights reserved
  • 21. Have a clear, unambiguous advantage in either effectiveness or cost-effectiveness Are compatible with the adopter’s values, norms, and perceived needs Are perceived as simple to use Knowledge to use innovation can be codified and transferred easily When the technology can be refined and modified by the adopter to meet their specific needs Carries a low degree of uncertainty, i.e. they are perceived as having little risk. Observable benefits It is relevant to the user’s work and improves task performance Offer trialability - users can experiment on a limited basis Technology offered as an “augmented product” Greenhalgh, et al. The Milbank Quarterly, 82(4), 581–629.
  • 22. THE FUTURE Image source: Jerry Fahrni, Pharm.D. – All rights reserved
  • 25.
  • 27. External sensors - blood-pressure cuffs and pulse oximeters Wearables embedded in clothing or accessories Epidermal sensors, such as patches and digital tattoos Ingestibles embedded in pills that dissolve Tissue-embedded sensors - pacemakers and defibrillators Blood-sampling sensors, such as glucose meters
  • 30. Selectively perforate bacterial cell membrane without affecting host cells Release antibiotic in presence of infection Target antibiotic to attack specific bacterial antigens Gold coated nano shells heated up with light to destroy cancer cells (Nanobullet) Smart Insulin – “Glucose Sensitive Insulin” Nano-artificial pancreas Biodegradable nanoparticles that release growth factors and angiogenic factors to improve bioengineering of heart or lung tissue
  • 31. The first 3D-printed drug to win FDA approval 3D Printing
  • 32. “It's like drinking from a fire hose” ~ Alfred Huger
  • 34. Professionals entrusted with the delivery and administrations of pharmaceuticals have a fundamental responsibility to identify and implement interventions that will improve patient quality outcome measures and also reduce overall health-care costs. These interventions include timely and judicious use of therapeutic and technological advances Meyer GE, et al. AJHP. 1991 May 1;48:953-966 “
  • 35. THE FUTURE OF PHARMACY: Using Technology to Drive Practice Change Jerry Fahrni, Pharm.D. || 559.838.6014 || @JFahrni

Editor's Notes

  1. Image source: http://hypothyroidmom.com/wp-content/uploads/2013/10/chicken-and-egg3.jpg [Licensed under creative commons]
  2. Bond CA, Raehl CL, Patry R. Evidence-Based Core Clinical Pharmacy Services in United States Hospitals in 2020: Services and Staffing, Pharmacotherapy 2004; 24(4):427-440 …. Adopted from Table 4 - Summary of Statistically Significant Associations of Clinical Pharmacy Services, Hospital Pharmacy  Staffing, and Pharmacist Location with Major Health Care Outcomes in Clinical Pharmacy Services in U.S. Hospitals in 2020 Bond et al, Pharmacotherapy 2004
  3. Strong Memorial Hospital (SMH) - part of the University of Rochester Medical Center (URMC) complex, in Rochester, New York –
  4. DIFFUSION OF INNOVATION THEORY - developed by E.M. Rogers in 1962.   [Rogers, E. M. & Shoemaker, F. F. (1971). Communication of Innovation. New York: The Free Press.]
  5. Harvard Business Review,. "The Pace Of Technology Adoption Is Speeding Up". N.p., 2013. Web. 20 Jan. 2016.
  6. [Greenhalgh, T., Robert, G., Macfarlane, F., Bate, P., and Kyriakidou, O. (2004). Diffusion of Innovations in Service Organizations: Systematic Review and Recommendations. The Milbank Quarterly, 82(4), 581–629. http://doi.org/10.1111/j.0887-378X.2004.00325.x]
  7. Image source: http://uploadvr.com/7-valuable-lessons-vr-ar-healthcare-education-industries/
  8. https://en.wikipedia.org/wiki/Transferase licensed under the Creative Commons Attribution-Share Alike 3.0 Unported ​
  9. First mobile insulin pump ... 1963
  10. http://www.computerworld.com/article/3048823/3d-printing/this-is-the-first-3d-printed-drug-to-win-fda-approval.html 3-Dimensional Drug Printing: Potential in the Pharmacy: ​ http://www.pharmacytimes.com/publications/issue/2013/august2013/3-dimensional-drug-printing-potential-in-the-pharmacy#sthash.GgD3f048.dpuf​ ​ Three-dimensional drug printing: A structured review​ http://www.japha.org/article/S1544-3191(15)30306-X/abstract​ ​ No need for the pharmacy; just press print [video – theophylline tablet]​ http://scienceline.org/2014/12/no-need-for-the-pharmacy-just-press-print/​
  11. “Professionals entrusted with the delivery and administrations of pharmaceuticals have a fundamental responsibility (moral obligation—MN) to identify and implement interventions that will improve patient quality outcome measures and also reduce overall health-care costs. These interventions include the timely and judicious use of therapeutic and technological advances.” Meyer GE, Brandell R, Smith JE, et al. "Use of bar codes in inpatient drug distribution" Am J Health Syst Pharm. 1991 May 1;48:953-966