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Newsflash
February 2014
New Data Available
Dengue NS1
Malaria

Capabilities
Monoclonal Antibodies
Polyclonal Antibodies
Recombinant Fab Antibodies

Quality

Partnership

Results

Innovation
Why choose BBI ?
 Be confident in your results when you
choose BBI’s monoclonal antibodies for
your next assay:





Tested in ELISA
Tested in Lateral Flow
Recommended pairings provided
Strong Customer Feedback

 We have now introduced highly sensitive
Recombinant Fab antibodies to improve
your next generation assays
 Custom development and manufacturing
services to meet your individual
requirements

Quick Links
Dengue NS1 Antibodies >
Malaria Antibodies >
Monoclonal Antibodies >
Polyclonal Antibodies >
Recombinant Fab
Antibodies >
How to Order >
Antibody Spotlight
NEW DATA – Dengue NS1 Antibodies
We have developed panels of antibodies for detecting the four different Dengue
subtypes. Our Dengue Antibodies can detect the presence of Dengue antigens
down to 0.5ng/ml or lower. The antibodies have been tested in patient samples.

Dengue Subtype 1

Detection of 0.5ng/ml antigen
concentration can be obtained with
our recommended pairings.

Lateral Flow using BM404-K2G4 as Capture
Antibody
Signal Strength (RANN Score)

Recommended Sandwich Pairings
Capture Antibody
Detection Antibody
BM404-K2G4
BM409-V8F1
BM404-K2G4
BM409-G3D1
BM409-P3B4
BM409-P3B4

12
10

8
6
4

BM409-V8F1

2

BM409-G3D1

0
500

50

5

0.5

0

Dengue NS1 Subtype 1 Antigen Concentration (ng/ml)

Return home >
Antibody Spotlight
NEW DATA – Dengue NS1 Antibodies
Dengue Subtype 2
Recommended Sandwich Pairings
Capture Antibody
Detection Antibody
BM339-T3H2
BM339-P3D8
BM339-T3H2
BM339-P6D8

We recommend these pairings for
Dengue Subtype 2 Antibodies for
use in Lateral Flow.

Dengue Subtype 3

Detection of 0.5ng/ml antigen
concentration can be obtained with
our recommended pairings.

Dengue Substype 3 Antibodies tested in
Lateral Flow
Signal Strength (RANN Score)

Recommended Sandwich Pairings
Capture Antibody
Detection Antibody
BM405-K9A5
BM406-F2E8
BM406-F2E8
BM405-K9A5

12
10
8

BM405-K9A5
(D), BM406-F3E8
(C)

6
4

BM406-F3E8
(D), BM406-K9A5
(C)

2
0
500

50

5

0.5

0

Dengue NS1 Subtype 3 Antigen Concentration (mg/ml)

Return home >
Antibody Spotlight
NEW DATA – Dengue NS1 Antibodies
Dengue Subtype 4

Detection of 0.5ng/ml antigen
concentration can be obtained with
our recommended pairings.

Lateral Flow using BM408-N9G5 as Capture
Signal Strength (RANN Score)

Recommended Sandwich Pairings
Capture Antibody
Detection Antibody
BM408-N9G5
BM407-K3A2
BM408-N9G5
BM408-G8E7
BM408-N9G5
BM408-M2B3
BM408-N9G5
BM408-F5F4
BM408-N9G5
BM408-E1D5

12
10
Detection Antibodies

8

BM407-K3A2

6

BM408-G8E7
BM408-M2B3

4

BM408-F5F4

2

BM408-E1D5

0
500

50

5

0.5

0

Dengue NS1 Antigen Subtype 4 Concentration (ng/mg)

Order your evaluation samples today:
info@bbisolutions.com | USA: 1-800-423-8199 | Intl: +44 (0) 2920 747 232
Return home >
Antibody Spotlight
NEW DATA – Malaria Antibodies
Our antibodies can detect the presence of Malaria antigen down to 0.5ng/ml or
lower. All of our Malaria antibodies have been tested in Lateral Flow using patient
samples.

Malaria HRP 2

Detection of 0.5ng/ml antigen
concentration can be obtained with
our recommended pairings.

Lateral Flow using BM340-F5D2 as Capture
Signal Strength (RANN Score)

Recommended Sandwich Pairings
Capture Antibody
Detection Antibody
BM340-F5D2
BM340-F5D2
BM340-F5D2
BM340-Z2D5
BM340-F5D2
BM340-U7D4
BM340-F5D2
BM340-S1F4

14

Detection
Antibodies

12
10

Z2D5

8

F5D2

6

U7D4

4

S1F4

2
0
100

10

2

0

Malaria HRP2 Concentration (mg/ml)

Return home >
Antibody Spotlight
NEW DATA – Malaria Antibodies
Malaria LDH pan (detects all Plasmodium species)
Recommended Sandwich Pairings
Capture Antibody
Detection Antibody

BM355-P2H3 or BM355-P4A2
BM355-P2G3 or BM355-P4A2

BM355-P4A2
BM244-Z8F7

Detection of 0.5ng/ml
antigen concentration can
be obtained with our
recommended pairings.

Signal Strength (RANN Score)

Lateral Flow for LDH (pan) Malaria Antibodies
12

BM355-P4A2 (D), BM355-P2H3 (C)

10

MB355-P4A2 (D), BM355-P4A2 (C)

8

BM244-Z8F7 (D), BM355-P2H3 (C)

6

BM244-Z8F7 (D), BM355-P4A2 (C)

4
2
0
1000

100

10

pLDH Malaria Antigen Concentration (ng/mg)

0

We also have a panel of P.
falciparum – specific LDH
antibodies available.
Return home >
Our Capabilities | Monoclonal Antibodies
Cardiac
CK-MB
D-Dimer
Myoglobin
Troponin I
Diabetes
Hb
HbA1c
Drugs of abuse
THCΔ9
Hormones
DHEA-S
Cortisol
Progesterone
PTH

Infectious Disease
C. difficile Toxin A
C. difficile Toxin B
Chikungunya
Dengue NS1
H. pylori
HAV
HBV
Hepatitis B
HIV p24
HIV gp35
HIV gp41
Influenza A
Influenza B
Leptospira
Listeria
Malaria HRP2
Malaria LHD (pan)
Malaria LHD (Pf)
Malaria LDH (Pf & Pv)

Norovirus
PBP2a
TB
Pregnancy
AFP
Tumour
CA125
CA15-3
CA19-9
Calcitonin
Immunoglobulins
IgA
IgE
IgG
IgM

Return home >
Our Capabilities | Polyclonal Antibodies
Inflammation
CRP

Pregnancy
AFP

Hormones
HCG
αHCG

Inflammatory
A1AT

Immunoglobulins
IgA
IgM
IgG
Albumin

Haematology
Haptoglobin
Ferritin
Haemoglobin

Renal
A2M
B2M
Cystatin C

Metabolism
Ceruloplasmin

Return home >
Our Capabilities | Recombinant Fab Antibodies
Biomarker

Detection Range*

Capture Antibody

Detection Antibody

HSP60

0.1 - 1200 ng/mL

BR100-G2A7

BR100-H4C2

Adiponectin

0.1 - 525 ng/mL

BR101-P7E2

BR101-M3H8

Adiponectin

230 - 59118 ng/mL

BR101-H2B4 (Competitive ELISA)

Angiopoietin 2

0.001 - 97 ng/mL

BR103-P4E8

BR103-V5F2

Big Endothelin 1

0.001 - 1.8 ng/mL

BR104-D6A4

BR104-H1A4

Calcitonin

0.006 - 2 ng/mL

BR388-G6B1

BR388-D5C4

Cathepsin D

0.03 - 150 ng/mL

BR107-F5G2

BR107-K6D3

Eotaxin

0.007 - 2 ng/mL

BR108-M7H3

BR108-K2D9

Chondrolectin

0.9 - 21 ng/mL

BR111-P8G3

BR111-T6B1

CKBB

0.15 - 33 ng/mL

BR112-V6F6

BR112-Z1C4

Proinsulin C-Peptide

0.09 - 38 ng/mL

BR143-G5D3

BR143-K7C9

CRP

151 - 231000 ng/mL

BR228-D4A3 (Competitive ELISA)

Cystatin C

165 - 9073 ng/mL

BR175-G8D9 (Competitive ELISA)

Cystatin C

165 - 9073 ng/mL

BR175-H4C8 (Competitive ELISA)

E. histolytica

not tested

BR116-K9F7

BR116-G3A1

E-selectin

0.05 - 235 ng/mL

BR117-K2E7

BR117-H5B6

FABP Intestine

0.65 - 100 ng/mL

BR115-F7G7

BR115-G6B9

FABP Liver

0.03 - 90 ng/mL

BR106-G5A2

BR106-P9F5

* Detection Ranges are assay dependent and optimised for specific
clinical conditions, therefore may be improved with optimisation

Return home >
Our Capabilities | Recombinant Fab Antibodies
Biomarker
G. lamblia

Detection Range*
not tested

Capture Antibody

Detection Antibody

BR120-P3F2 & BR120-T1G8

Human Fetal Hemoglobin

1.9 - 305 ng/mL

BR121-T5H9

BR121-V5A7

Leptin

3.9 - 691 ng/mL

BR123-M4D6

BR123-P4G2

MMP7

0.1 - 293 ng/mL

BR124-S4E3

BR124-T6G8

MMP9 Active

11 - 183 ng/mL

BR125-N5F7

BR125-M6D6

MPO

2 - 1200 ng/mL

BR240-N5G6

BR240-D8B4

Neutrophil Elastase

0.008 - 33 ng/mL

BR127-H2A4

BR127-G7C2

Free PAPP A

0.3 - 299 ng/mL

BR129-M5E3

BR129-F2H4

Pentraxin 3

4.6 - 876 ng/mL

BR130-H2C3

BR130-K6D6

PGDS

0.2 - 85 ng/mL

BR131-M6H7

BR131-P7F7

PSAP A

0.013 - 123 ng/mL

BR132-T5G4

BR132-S6E4

PSAP B

0.3 - 1500 ng/mL

BR133-V6B5

BR133-V4D1

RBP 4

350 - 500000 ng/mL

BR134-Z7D3 (Competitive ELISA)

S100 Beta

0.04 - 5.6 ng/mL

BR332-G4B9

BR332-F5H7

ST2

1.39 - 97 ng/mL

BR139-S7B7

BR139-V8D4

ST2

0.08 - 31 ng/mL

BR139-T3G5

BR139-V8D4

Tie2

0.8 - 600 ng/mL

BR140-Z7A5

BR140-D9D7

* Detection Ranges are assay dependent and optimised for specific
clinical conditions, therefore may be improved with optimisation

Return home >
How to Order
info@bbisolutions.com
Please get in touch to arrange a quote for
any of our products.

USA: 1-800-423-8199
Intl: +44 (0) 2920 747 232

Quote on ordering – NF FEB

BBI Solutions

bbisolutions1

Return home >

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Antibodies Newsflash - February 2014 - BBI Solutions

  • 1. Newsflash February 2014 New Data Available Dengue NS1 Malaria Capabilities Monoclonal Antibodies Polyclonal Antibodies Recombinant Fab Antibodies Quality Partnership Results Innovation
  • 2. Why choose BBI ?  Be confident in your results when you choose BBI’s monoclonal antibodies for your next assay:     Tested in ELISA Tested in Lateral Flow Recommended pairings provided Strong Customer Feedback  We have now introduced highly sensitive Recombinant Fab antibodies to improve your next generation assays  Custom development and manufacturing services to meet your individual requirements Quick Links Dengue NS1 Antibodies > Malaria Antibodies > Monoclonal Antibodies > Polyclonal Antibodies > Recombinant Fab Antibodies > How to Order >
  • 3. Antibody Spotlight NEW DATA – Dengue NS1 Antibodies We have developed panels of antibodies for detecting the four different Dengue subtypes. Our Dengue Antibodies can detect the presence of Dengue antigens down to 0.5ng/ml or lower. The antibodies have been tested in patient samples. Dengue Subtype 1 Detection of 0.5ng/ml antigen concentration can be obtained with our recommended pairings. Lateral Flow using BM404-K2G4 as Capture Antibody Signal Strength (RANN Score) Recommended Sandwich Pairings Capture Antibody Detection Antibody BM404-K2G4 BM409-V8F1 BM404-K2G4 BM409-G3D1 BM409-P3B4 BM409-P3B4 12 10 8 6 4 BM409-V8F1 2 BM409-G3D1 0 500 50 5 0.5 0 Dengue NS1 Subtype 1 Antigen Concentration (ng/ml) Return home >
  • 4. Antibody Spotlight NEW DATA – Dengue NS1 Antibodies Dengue Subtype 2 Recommended Sandwich Pairings Capture Antibody Detection Antibody BM339-T3H2 BM339-P3D8 BM339-T3H2 BM339-P6D8 We recommend these pairings for Dengue Subtype 2 Antibodies for use in Lateral Flow. Dengue Subtype 3 Detection of 0.5ng/ml antigen concentration can be obtained with our recommended pairings. Dengue Substype 3 Antibodies tested in Lateral Flow Signal Strength (RANN Score) Recommended Sandwich Pairings Capture Antibody Detection Antibody BM405-K9A5 BM406-F2E8 BM406-F2E8 BM405-K9A5 12 10 8 BM405-K9A5 (D), BM406-F3E8 (C) 6 4 BM406-F3E8 (D), BM406-K9A5 (C) 2 0 500 50 5 0.5 0 Dengue NS1 Subtype 3 Antigen Concentration (mg/ml) Return home >
  • 5. Antibody Spotlight NEW DATA – Dengue NS1 Antibodies Dengue Subtype 4 Detection of 0.5ng/ml antigen concentration can be obtained with our recommended pairings. Lateral Flow using BM408-N9G5 as Capture Signal Strength (RANN Score) Recommended Sandwich Pairings Capture Antibody Detection Antibody BM408-N9G5 BM407-K3A2 BM408-N9G5 BM408-G8E7 BM408-N9G5 BM408-M2B3 BM408-N9G5 BM408-F5F4 BM408-N9G5 BM408-E1D5 12 10 Detection Antibodies 8 BM407-K3A2 6 BM408-G8E7 BM408-M2B3 4 BM408-F5F4 2 BM408-E1D5 0 500 50 5 0.5 0 Dengue NS1 Antigen Subtype 4 Concentration (ng/mg) Order your evaluation samples today: info@bbisolutions.com | USA: 1-800-423-8199 | Intl: +44 (0) 2920 747 232 Return home >
  • 6. Antibody Spotlight NEW DATA – Malaria Antibodies Our antibodies can detect the presence of Malaria antigen down to 0.5ng/ml or lower. All of our Malaria antibodies have been tested in Lateral Flow using patient samples. Malaria HRP 2 Detection of 0.5ng/ml antigen concentration can be obtained with our recommended pairings. Lateral Flow using BM340-F5D2 as Capture Signal Strength (RANN Score) Recommended Sandwich Pairings Capture Antibody Detection Antibody BM340-F5D2 BM340-F5D2 BM340-F5D2 BM340-Z2D5 BM340-F5D2 BM340-U7D4 BM340-F5D2 BM340-S1F4 14 Detection Antibodies 12 10 Z2D5 8 F5D2 6 U7D4 4 S1F4 2 0 100 10 2 0 Malaria HRP2 Concentration (mg/ml) Return home >
  • 7. Antibody Spotlight NEW DATA – Malaria Antibodies Malaria LDH pan (detects all Plasmodium species) Recommended Sandwich Pairings Capture Antibody Detection Antibody BM355-P2H3 or BM355-P4A2 BM355-P2G3 or BM355-P4A2 BM355-P4A2 BM244-Z8F7 Detection of 0.5ng/ml antigen concentration can be obtained with our recommended pairings. Signal Strength (RANN Score) Lateral Flow for LDH (pan) Malaria Antibodies 12 BM355-P4A2 (D), BM355-P2H3 (C) 10 MB355-P4A2 (D), BM355-P4A2 (C) 8 BM244-Z8F7 (D), BM355-P2H3 (C) 6 BM244-Z8F7 (D), BM355-P4A2 (C) 4 2 0 1000 100 10 pLDH Malaria Antigen Concentration (ng/mg) 0 We also have a panel of P. falciparum – specific LDH antibodies available. Return home >
  • 8. Our Capabilities | Monoclonal Antibodies Cardiac CK-MB D-Dimer Myoglobin Troponin I Diabetes Hb HbA1c Drugs of abuse THCΔ9 Hormones DHEA-S Cortisol Progesterone PTH Infectious Disease C. difficile Toxin A C. difficile Toxin B Chikungunya Dengue NS1 H. pylori HAV HBV Hepatitis B HIV p24 HIV gp35 HIV gp41 Influenza A Influenza B Leptospira Listeria Malaria HRP2 Malaria LHD (pan) Malaria LHD (Pf) Malaria LDH (Pf & Pv) Norovirus PBP2a TB Pregnancy AFP Tumour CA125 CA15-3 CA19-9 Calcitonin Immunoglobulins IgA IgE IgG IgM Return home >
  • 9. Our Capabilities | Polyclonal Antibodies Inflammation CRP Pregnancy AFP Hormones HCG αHCG Inflammatory A1AT Immunoglobulins IgA IgM IgG Albumin Haematology Haptoglobin Ferritin Haemoglobin Renal A2M B2M Cystatin C Metabolism Ceruloplasmin Return home >
  • 10. Our Capabilities | Recombinant Fab Antibodies Biomarker Detection Range* Capture Antibody Detection Antibody HSP60 0.1 - 1200 ng/mL BR100-G2A7 BR100-H4C2 Adiponectin 0.1 - 525 ng/mL BR101-P7E2 BR101-M3H8 Adiponectin 230 - 59118 ng/mL BR101-H2B4 (Competitive ELISA) Angiopoietin 2 0.001 - 97 ng/mL BR103-P4E8 BR103-V5F2 Big Endothelin 1 0.001 - 1.8 ng/mL BR104-D6A4 BR104-H1A4 Calcitonin 0.006 - 2 ng/mL BR388-G6B1 BR388-D5C4 Cathepsin D 0.03 - 150 ng/mL BR107-F5G2 BR107-K6D3 Eotaxin 0.007 - 2 ng/mL BR108-M7H3 BR108-K2D9 Chondrolectin 0.9 - 21 ng/mL BR111-P8G3 BR111-T6B1 CKBB 0.15 - 33 ng/mL BR112-V6F6 BR112-Z1C4 Proinsulin C-Peptide 0.09 - 38 ng/mL BR143-G5D3 BR143-K7C9 CRP 151 - 231000 ng/mL BR228-D4A3 (Competitive ELISA) Cystatin C 165 - 9073 ng/mL BR175-G8D9 (Competitive ELISA) Cystatin C 165 - 9073 ng/mL BR175-H4C8 (Competitive ELISA) E. histolytica not tested BR116-K9F7 BR116-G3A1 E-selectin 0.05 - 235 ng/mL BR117-K2E7 BR117-H5B6 FABP Intestine 0.65 - 100 ng/mL BR115-F7G7 BR115-G6B9 FABP Liver 0.03 - 90 ng/mL BR106-G5A2 BR106-P9F5 * Detection Ranges are assay dependent and optimised for specific clinical conditions, therefore may be improved with optimisation Return home >
  • 11. Our Capabilities | Recombinant Fab Antibodies Biomarker G. lamblia Detection Range* not tested Capture Antibody Detection Antibody BR120-P3F2 & BR120-T1G8 Human Fetal Hemoglobin 1.9 - 305 ng/mL BR121-T5H9 BR121-V5A7 Leptin 3.9 - 691 ng/mL BR123-M4D6 BR123-P4G2 MMP7 0.1 - 293 ng/mL BR124-S4E3 BR124-T6G8 MMP9 Active 11 - 183 ng/mL BR125-N5F7 BR125-M6D6 MPO 2 - 1200 ng/mL BR240-N5G6 BR240-D8B4 Neutrophil Elastase 0.008 - 33 ng/mL BR127-H2A4 BR127-G7C2 Free PAPP A 0.3 - 299 ng/mL BR129-M5E3 BR129-F2H4 Pentraxin 3 4.6 - 876 ng/mL BR130-H2C3 BR130-K6D6 PGDS 0.2 - 85 ng/mL BR131-M6H7 BR131-P7F7 PSAP A 0.013 - 123 ng/mL BR132-T5G4 BR132-S6E4 PSAP B 0.3 - 1500 ng/mL BR133-V6B5 BR133-V4D1 RBP 4 350 - 500000 ng/mL BR134-Z7D3 (Competitive ELISA) S100 Beta 0.04 - 5.6 ng/mL BR332-G4B9 BR332-F5H7 ST2 1.39 - 97 ng/mL BR139-S7B7 BR139-V8D4 ST2 0.08 - 31 ng/mL BR139-T3G5 BR139-V8D4 Tie2 0.8 - 600 ng/mL BR140-Z7A5 BR140-D9D7 * Detection Ranges are assay dependent and optimised for specific clinical conditions, therefore may be improved with optimisation Return home >
  • 12. How to Order info@bbisolutions.com Please get in touch to arrange a quote for any of our products. USA: 1-800-423-8199 Intl: +44 (0) 2920 747 232 Quote on ordering – NF FEB BBI Solutions bbisolutions1 Return home >