O Caixa Empreender Award atribuiu um valor de investimento adicional, no valor de 100 mil euros, ao projeto que mais se destacou de um conjunto de 7 startups, previamente selecionadas no âmbito dos programas de aceleração que contam com o apoio do Grupo CGD, BGI, Lisbon Challenge e ACT by COTEC. A Thelial foi uma das startups presentes no Caixa Empreender. #thefuturefromscratch Mais sobre o objetivo deste evento em: http://bit.ly/1CzA5BV

1. Thelial
– next generation sun care
Contact: Richard Hampson Ph.D.
rhampson@thelial.com

2. Non-melanoma skin cancer
• 3.5M cases per year in USA.
• principal cause – UV from sunlight.

3. Current solution: UV protection
• Sun care protects from UV induced skin
cancer.
• Only UV protector
clinically proven
to reduce skin
cancer incidence.

4. Need
• Sun care that moves beyond sun
protection factor (SPF).

5. Drivers
• Consumer preference.
• Medical need.
• Legal requirements.

6. Occupational health – sun care

7. Our solution
• Adds active cancer prophylaxis to sun
care.
• Prevents 80% of UV induced skin cancer
(mouse tests).
• Non-toxic natural compound.

8. Uniqueness:
Targeting cell polarity.

9. We seek funds to:
• Complete final animal tests.
• Formulate.
• Clinical trials completing efficacy studies.
Complete financing need 2.5 M€.

10. How? Affordable development in a
high cost space.
• Established ingredients.
• Accelerated clinical tests in established
high need patient populations.
• Global selection of high need
geographies.

11. Global market size
• Specialist products for high need
populations: 100M US$.
• OTC products: 10B US$.

12. IP
• Secondary medical indication1.
• Formulation.
• Other e.g. packaging.
(1) Provisional patent applications PT2014000049856 and
PT2014000177080.

13. Competition
high SPF
clinically proven
anti-cancer
anti-cancer &
beyond SPF
SPF50

14. Next plans
• Tests & formulation (6 months).
• Proof of concept in patients (phase 2a;
6-24 months).
• Licensing/sale.
Financing need: 2.5M €.

15. Team
Richard Hampson
• University of London, Harvard University.
• Oryzon, Barcelona.
• Lead promoter since 2009.
Rui Martinho
• University of Sussex, New York University.
• Instituto Gulbenkian, University Algarve.
• Co-promoter since 2009.

16. Advisors – sun care
• Skin cancer center, Charité Hospital, Berlin.
• The team behind:

17. Advisors mean expertise:
• Dispensers.
• High need population already recruited.
• Non-invasive clinical monitoring.
• Regulatory needs: the US market.

18. Thelial
– next generation sun care
Contact: Richard Hampson Ph.D.
rhampson@thelial.com