Biohacking: hack je DNA
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Presentatie van mij en Terry Vrijenhoek over DNA hacking, analyse van je genen, bioterreur en opslag van data in DNA.
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Biohacking: hack je DNA
- 1. Biohacking Meetup 1 december 2015: DNA Hacking en meer
- 2. Wie ben ik?
- 3. Wat is biohacking? Optimaliseren van lichaam en geest Cyborgs Symbiose van mens en machine Onsterfelijkheid Klooien aan je lijf … projectleven.nl
- 4. Biohacking Body/Mind hacking 3D bio-printing DNA/RNA hacking DIY Grinding QS / Quantified Self Life enhancement & Life extension The Singularity Transhumanisme
- 5. Biohacking Body/Mind hacking 3D bio-printing DNA/RNA hacking DIY Grinding QS / Quantified Self Life enhancement & Life extension The Singularity Transhumanisme
- 6. DNA Hacking en meer Terry Vrijenhoek (UMC Utrecht) - Wat is genomics? - Toepassingen van genomics - DNA/RNA hacking - Opslag van data in DNA - Q&A projectleven.nl
- 7. Come on, hack my DNA @terryvrijenhoek
- 8. “Dad?! WTF?!!” A DNA test to give you answers?! You know that is impossble, right?! Seriously?! A medical specialist, a genetic counselor, a clinical geneticist, a lab specialist, a bioinformatician and a social worker?! And 3 forms?! For a simple DNA test?! A doctor who interprets your genetic profile?! Wasn’t there an app for that?! No one could use your genetic data?! Then why did you generate them?! You and mum got me without prior knowledge?! How have you been able to LIVE?!!
- 9. Tegenwoordig is de medische wetenschap meer overtuigd van epigenetica
- 10. Genetic testing throughout life From womb to tomb -2 Birth planning - Carrier screening -0.5 Pregnancy - NIPT trisomy 13/18/21, gender Birth - Heel prick: carriership hereditary conditions 0 0-10 Unexplained inborn defects - De novo mutation screening - Whole genome sequencing 10-20 Disease prevention - BRCA, CFTR Cancer - Personalised treatment >50 Pharmacogenetics - Drug profiling 60 Aging - Growing old gracefully >100 Post-mortal - Molecular autopsy
- 12. Klinkt dit nu nog heel futuristisch? Nee hoor, bijvoorbeeld: de prijs om je hele DNA set te analyseren is spectaculair gedaald in maar een paar jaar tijd.
- 16. Dus bij mensen die een been zijn verloren, dat deze automatisch weer kan aangroeien? Kunnen we virussen maken die ons beschermen tegen alle ziektes? Worden we een soort supermensen door DNA hacking?
- 18. Op de Biohacker Summit in Helsinki hoorden Kim, Martijn en ik een presentatie van Nell Watson over de opslag van informatie in DNA
- 19. The five files comprised all 154 of Shakespeare’s sonnets (ASCII text), a classic scientific paper18 (PDF format), a m
- 21. Is dat het dan?
- 24. “Dad?! WTF?!!” A DNA test to give you answers?! You know that is impossble, right?! Seriously?! A medical specialist, a genetic counselor, a clinical geneticist, a lab specialist, a bioinformatician and a social worker?! And 3 forms?! For a simple DNA test?! A doctor who interprets your genetic profile?! Wasn’t there an app for that?! No one could use your genetic data?! Then why did you generate them?! You and mum got me without prior knowledge?! How have you been able to LIVE?!!
- 26. Vervolg A. Januari 2015 – Utrecht: Brainhacking en meer B. Verslag volgt op: www.projectleven.nl projectleven.nl
Editor's Notes
- Well, first of all, we overlook that genetics plays a role in an increasing number of life stages, and will eventually be important throughout life. Yet many issues around personal genomes are considered within their tradiotinal context. For example, a specific regalutaroy framework has recently been developed around NIPT, but there has been hardly any consideration on how NIPT data could be used in later stages of life. Now, likely there are many more elephants that we do not see at the moment. A good way to bring these elephants to the surface, is by simulating some scenarios that may occur when personal genome sequencing is broadly applied.
- To show what I mean, I would to introduce to you Michael Snyder, professor at Stanford University and director of the Stanford Center for Genomics and Personalised Medicine. He is just an ordinary professor, with a lab, some PhD students, postdocs, and a couple of sequencing machines and mass spectrometers. But professoor Snyder is also this, a large collection of DNA sequences, metabolic profiles expressed proteins etc. For more than 14 months, Snyder had his lab subject him to a variety of –omics measurements. He had his entire genome sequenced, had blood drawn regularly for extensive omics profiling and glucose measurement. Identified susceptibility for diabetes, and developed diabetes, two viral infextions, and events of RNA editing