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4th year MBChB Anaesthesia Tutorial
Concepts
 Regional anaesthesia affects one part of the body only
 Remember the Triad of Anaesthesia:
 Analgesia
 Muscle Relaxation
 Hypnosis
Types of Regional Anaesthesia
 Topical Application
 Infiltration
 Intravenous Regional Anaesthesia of the Arm (Bier’s
Block)
 Peripheral Nerve Block
 Central Nerve Block(Neuraxial Blockade)
Topical
 Aerosolised
 2% lignocaine in MacIntosh sprayer for vocal cords
 Cream
 Direct Application
 drops
Infiltration
 Subcutaneously
 Intradermally
Bier’s Block
Bier’s Block
Peripheral Nerve Block
Nerve location with Ultrasound
Central Nerve Blockade
Is a central nerve block good
enough for surgery?
 Yes!
 Excellent operating conditions
 Sensory block – interrupts somatic and visceral painful
stimuli
 Motor block – skeletal muscle relaxation
 Triad of anaesthesia: hypnosis
muscle
relaxation
analgesia
Subarachnoid Space (SAS)
Vertebral Column
Applied Anatomy
 Spinal anaesthesia
 LA deposited into CSF
 Blockade of nerve roots as they pass through the
subarachnoid space
 Subarachnoid space is deep to the dura and arachnoid
mater
 Spinal portion of SAS extends from foramen magnum
superiorly to S2 inferiorly
 Spinal cord ends at L1/2
Applied Anatomy
 Epidural Anaesthesia:
 Epidural space lies outside dura
 “epi”- Greek for on, at, across or against
 The nerve roots pass through this space as they leave the
spinal cord
 The epidural space is a potential space with a negative
pressure
 Contains: fatty connective tissue, lymphatics and a venous
plexus
Epidural Space
Epidural space – cross-section
Epidural injection
Epidural injection and spread of LA
Indications for Neuraxial Blocks
 Alone or with a GA
 Alone:
 Lower abdominal
 Inguinal
 Urology
 Gynaecology
 Rectal Lower extremity surgery
Contra-indications: ABSOLUTE
 Patient refusal
 Local infection at the site
 Coagulopathy
 Platelets < 75
 INR > 1.5
 Severe hypovolaemia
 ↑ed ICP
 Fixed C.O. States: severe AS or MS and HOCM
 LA allergy
Contra-indications: RELATIVE
 Systemic sepsis
 Unco-operative patient
 Psychiatric
 Blind / Deaf
 Mentally challenged
 Pre-existing neurological deficits
 Stenotic valvular heart lesions
 Severe spinal deformity
 Previous spinal surgery
 Complicated surgery where block would not last long enough
or be inappropriate
Advantages
 Pre-emptive analgesia
 Post-op analgesia
 Usually less physiologic derangements
 Rapid post-op recovery
 No airway instrumentation and the complications
associated with it
 No GA and associated complications (aspiration, failed
intubation, PONV, MH)
 ↓ed DVTs
Complications
 Hypotension
 High spinal
 Post-dural puncture headache
 Meningitis and epidural abscess
 Epidural haematoma
 Neurological sequelae
 Urinary retention
 Pruritis
 Shivering
 Backache??? controversial
Hypotension
 Mechanism
 Vasodilatation
 Sympathetic blockade
 Thoracolumbar T1-L2
 Treatment:
 Elevate legs
 IV fluids
 Vasopressors
 Ephedrine: 5mg bolus
 Phenylephrine: 50ug bolus
 Adrenaline if unresponsive
to above measures
High spinal
 Presentation:
 Severe hypotension
 Bradycardia
 Block the cardiac
accelerator fibres
 Difficulty breathing
 Loss of consciousness
 Management:
 IV Fluids
 Vasopressors
 Atropine
 Intubation and
ventilation
 Adrenaline
Post-dural puncture headache
 Mechanism:
 CSF leak from a hole in the
dura left by the needle
 Traction on dura
 Meningitis-like headache
 Incidence:
 Higher with epidurals (1%)
 Prevention:
 Smaller gauge needles
 Pencil point needles
 Loss of resistance technique
with spinals
 Treatment:
 Conservative
 Bedrest
 IV Fluids
 Simple analgesia
 Opiates
 Laxatives
 Epidural Blood Patch
 99% success with injection
Neurological Sequelae
 Neuropraxias:
 Transient
 Nerve root damage from
needle
 Paralysis:
 Direct damage
 Epidural haematoma
 Monitor patient for return
of motor function
 Emergency
 Urgent MRI
 Must be released within 6
hours
 laminectomy
Minor complications
 Shivering:
 Treatment: iv Pethidine 10 – 25mg; 1mg propofol; clonidine
 Pruritis:
 From opiate in spinal / epidural
 Treatment: naloxone
 Urinary retention:
 catheterise
 Backache:
 Neuraxial anaesthesia will not make backache worse
Peri-operative Care
 Pre-op:
 Assessment same as for GA
(must be suitable for GA, in
the event that you need to
convert to GA)
 Starved
 Premed
 Full theatre preparation
 Intra-op:
 Monitors: ECG, NIBP, pulse
oximeter, etCO2
 Supplemental oxygen
 Sedation
 Prevent hypothermia
 Post-op:
 Block should be receding
 If no return of motor function
within 6 hours: be concerned
re epidural haematoma
 Timing of anticoagulation
How to do a spinal ...
 Preparation: patient,
theatre, consent
 IV line: 18G 0r 16G
running well
 Monitors: ECG, NIBP, Sats
 Positioning of patient
 Strict asepsis
 Cleaning and draping
 Draw up drugs
 Find landmarks
 L4/5 level of the iliac
crest (Tuffiers Line)
 LA infiltration
 Introducer at best space (L3/4
or L4/5) in midline
 Insert pp needle – angle
caudally
 Feel “gives” as pass through
ligaments, then dura
 Remove stylet and confirm CSF
flow in all directions
 Attach syringe, aspirate to
confirm correct place
 Inject slowly over 10 sec
Quincke
Whitacre
Spinal Needles
Factors influencing the height
of the block
 Patient position or posture
 During injection
 After injection
 Specific gravity of solution
 Volume of drugs
 Volume of CSF
 Site (interspace)
 Force & rate of injection
 Barbotage
 Age, height, weight
Specific Gravity
 CSF has a SG of 1,004.
 Solutions with a higher SG (heavier) with sink in the SAS,
they are gravity-dependent
 Hyperbaric: “heavy” solutions - bupivacaine with dextrose
 Isobaric: plain bupivacaine or lignocaine
Opiates
 Fentanyl or morphine @ GSH
 Diamorphine, pethidine, sufentanil, alfentanil
 Effect:
 Extends the duration of action
 Enhances analgesia
 Can be used alone, without LA, to give analgesia (block
sensory nerves only)
 Side-effect: pruritis, can be severe
Epidurals
 Definition:
 LA placed into the epidural space at lumbar or thoracic
level, via epidural catheter
 Advantages:
 Placement of epidural catheter allows for a constant
infusion or top-up doses
 PCEA: Patient-controlled epidural anaesthesia
 Opiates enhance post-operative analgesia
 Graded block – slow establishment of level avoids the rapid
haemodynamic changes
 Uses:
 With GA
 Thoracic epidural for
thoracic surgery
 Abdominal surgery
 Hip and leg surgery
 Labour epidural for
analgesia
 Post-op analgesia
 Chronic Pain treatment
Epidural set
Epidural technique
“Loss of resistance”
Epidural strapped in place
Patient Preparation
 As for General Anaesthesia
 Full history, examination and relevant special
investigations
 Starved
 Decent IV Access
Theatre preparation
 Anaesthetic machine checked
 or ability to ventilate and give O2
 Airway trolley
 Defibrillator
 Suction
 Anaesthetic drugs
 Emergency drugs
Benefits of Regional Anaesthesia
 Pre-emptive analgesia
 Post-op analgesia
 Haemodynamically stable
 Rapid recovery post-op
 Reduced surgical stress response
 Reduced GA complications
 Avoid airway instrumentation and it’s complications
 Reduce PONV
 Reduced DVT in ortho
Questions...

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MBChB Anaesthesia Regional Techniques

  • 1. 4th year MBChB Anaesthesia Tutorial
  • 2. Concepts  Regional anaesthesia affects one part of the body only  Remember the Triad of Anaesthesia:  Analgesia  Muscle Relaxation  Hypnosis
  • 3. Types of Regional Anaesthesia  Topical Application  Infiltration  Intravenous Regional Anaesthesia of the Arm (Bier’s Block)  Peripheral Nerve Block  Central Nerve Block(Neuraxial Blockade)
  • 4. Topical  Aerosolised  2% lignocaine in MacIntosh sprayer for vocal cords  Cream  Direct Application  drops
  • 9. Nerve location with Ultrasound
  • 11. Is a central nerve block good enough for surgery?  Yes!  Excellent operating conditions  Sensory block – interrupts somatic and visceral painful stimuli  Motor block – skeletal muscle relaxation  Triad of anaesthesia: hypnosis muscle relaxation analgesia
  • 14. Applied Anatomy  Spinal anaesthesia  LA deposited into CSF  Blockade of nerve roots as they pass through the subarachnoid space  Subarachnoid space is deep to the dura and arachnoid mater  Spinal portion of SAS extends from foramen magnum superiorly to S2 inferiorly  Spinal cord ends at L1/2
  • 15. Applied Anatomy  Epidural Anaesthesia:  Epidural space lies outside dura  “epi”- Greek for on, at, across or against  The nerve roots pass through this space as they leave the spinal cord  The epidural space is a potential space with a negative pressure  Contains: fatty connective tissue, lymphatics and a venous plexus
  • 17. Epidural space – cross-section
  • 19. Epidural injection and spread of LA
  • 20. Indications for Neuraxial Blocks  Alone or with a GA  Alone:  Lower abdominal  Inguinal  Urology  Gynaecology  Rectal Lower extremity surgery
  • 21. Contra-indications: ABSOLUTE  Patient refusal  Local infection at the site  Coagulopathy  Platelets < 75  INR > 1.5  Severe hypovolaemia  ↑ed ICP  Fixed C.O. States: severe AS or MS and HOCM  LA allergy
  • 22. Contra-indications: RELATIVE  Systemic sepsis  Unco-operative patient  Psychiatric  Blind / Deaf  Mentally challenged  Pre-existing neurological deficits  Stenotic valvular heart lesions  Severe spinal deformity  Previous spinal surgery  Complicated surgery where block would not last long enough or be inappropriate
  • 23. Advantages  Pre-emptive analgesia  Post-op analgesia  Usually less physiologic derangements  Rapid post-op recovery  No airway instrumentation and the complications associated with it  No GA and associated complications (aspiration, failed intubation, PONV, MH)  ↓ed DVTs
  • 24. Complications  Hypotension  High spinal  Post-dural puncture headache  Meningitis and epidural abscess  Epidural haematoma  Neurological sequelae  Urinary retention  Pruritis  Shivering  Backache??? controversial
  • 25. Hypotension  Mechanism  Vasodilatation  Sympathetic blockade  Thoracolumbar T1-L2  Treatment:  Elevate legs  IV fluids  Vasopressors  Ephedrine: 5mg bolus  Phenylephrine: 50ug bolus  Adrenaline if unresponsive to above measures
  • 26. High spinal  Presentation:  Severe hypotension  Bradycardia  Block the cardiac accelerator fibres  Difficulty breathing  Loss of consciousness  Management:  IV Fluids  Vasopressors  Atropine  Intubation and ventilation  Adrenaline
  • 27. Post-dural puncture headache  Mechanism:  CSF leak from a hole in the dura left by the needle  Traction on dura  Meningitis-like headache  Incidence:  Higher with epidurals (1%)  Prevention:  Smaller gauge needles  Pencil point needles  Loss of resistance technique with spinals  Treatment:  Conservative  Bedrest  IV Fluids  Simple analgesia  Opiates  Laxatives  Epidural Blood Patch  99% success with injection
  • 28. Neurological Sequelae  Neuropraxias:  Transient  Nerve root damage from needle  Paralysis:  Direct damage  Epidural haematoma  Monitor patient for return of motor function  Emergency  Urgent MRI  Must be released within 6 hours  laminectomy
  • 29. Minor complications  Shivering:  Treatment: iv Pethidine 10 – 25mg; 1mg propofol; clonidine  Pruritis:  From opiate in spinal / epidural  Treatment: naloxone  Urinary retention:  catheterise  Backache:  Neuraxial anaesthesia will not make backache worse
  • 30. Peri-operative Care  Pre-op:  Assessment same as for GA (must be suitable for GA, in the event that you need to convert to GA)  Starved  Premed  Full theatre preparation  Intra-op:  Monitors: ECG, NIBP, pulse oximeter, etCO2  Supplemental oxygen  Sedation  Prevent hypothermia  Post-op:  Block should be receding  If no return of motor function within 6 hours: be concerned re epidural haematoma  Timing of anticoagulation
  • 31. How to do a spinal ...  Preparation: patient, theatre, consent  IV line: 18G 0r 16G running well  Monitors: ECG, NIBP, Sats  Positioning of patient  Strict asepsis  Cleaning and draping  Draw up drugs  Find landmarks  L4/5 level of the iliac crest (Tuffiers Line)
  • 32.  LA infiltration  Introducer at best space (L3/4 or L4/5) in midline  Insert pp needle – angle caudally  Feel “gives” as pass through ligaments, then dura  Remove stylet and confirm CSF flow in all directions  Attach syringe, aspirate to confirm correct place  Inject slowly over 10 sec
  • 34. Factors influencing the height of the block  Patient position or posture  During injection  After injection  Specific gravity of solution  Volume of drugs  Volume of CSF  Site (interspace)  Force & rate of injection  Barbotage  Age, height, weight
  • 35. Specific Gravity  CSF has a SG of 1,004.  Solutions with a higher SG (heavier) with sink in the SAS, they are gravity-dependent  Hyperbaric: “heavy” solutions - bupivacaine with dextrose  Isobaric: plain bupivacaine or lignocaine
  • 36. Opiates  Fentanyl or morphine @ GSH  Diamorphine, pethidine, sufentanil, alfentanil  Effect:  Extends the duration of action  Enhances analgesia  Can be used alone, without LA, to give analgesia (block sensory nerves only)  Side-effect: pruritis, can be severe
  • 37. Epidurals  Definition:  LA placed into the epidural space at lumbar or thoracic level, via epidural catheter  Advantages:  Placement of epidural catheter allows for a constant infusion or top-up doses  PCEA: Patient-controlled epidural anaesthesia  Opiates enhance post-operative analgesia  Graded block – slow establishment of level avoids the rapid haemodynamic changes
  • 38.  Uses:  With GA  Thoracic epidural for thoracic surgery  Abdominal surgery  Hip and leg surgery  Labour epidural for analgesia  Post-op analgesia  Chronic Pain treatment
  • 42.
  • 43. Patient Preparation  As for General Anaesthesia  Full history, examination and relevant special investigations  Starved  Decent IV Access
  • 44. Theatre preparation  Anaesthetic machine checked  or ability to ventilate and give O2  Airway trolley  Defibrillator  Suction  Anaesthetic drugs  Emergency drugs
  • 45. Benefits of Regional Anaesthesia  Pre-emptive analgesia  Post-op analgesia  Haemodynamically stable  Rapid recovery post-op  Reduced surgical stress response  Reduced GA complications  Avoid airway instrumentation and it’s complications  Reduce PONV  Reduced DVT in ortho