Small and medium enterprises (SMEs) in the retail and wholesale sectors represent a major source of growth, jobs, and innovation in the EU economy. SMEs in these sectors account for 5.4 million businesses across Europe, employing over 29 million people. While SMEs in retail and wholesale face challenges from digital transformation and regulatory burdens, they are also well-positioned to be flexible and innovative in meeting customer needs. The document calls for EU policies to better support SMEs in retail and wholesale in addressing challenges and capitalizing on opportunities.