Vitamin D in Chronic Kidney Disease Which type, Which dose, Which patient? - Dr. Gawad
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Vitamin D in Chronic Kidney Disease Which type, Which dose, Which patient? - Dr. Gawad
- 1. Mohammed Abdel Gawad MD Neph, ESENeph Lecturer of Nephrology, School of Medicine, NewGiza University NephrologyConsultant,Alexandria Founder of NephroTube.com Chairof AFRAN Web/Media Committee ISN Africa RegionalBoard drgawad@gmail.com Vitamin D in Chronic Kidney Disease Which type, Which dose, Which patient?
- 2. To download the lecture contact me drgawad@gmail.com For more Nephrology lectures visit www.NephroTube.com
- 5. LectureOutline • Vitamin D normal physiology and changes in CKD • Which vitamin D to measure at laboratory? Vitamin D level? • Vitamin D pleiotropic effect • Vitamin D use in CKD-MBD and vit D different forms/dosage • Hypomagnesemia and vitamin D deficiency in CKD • Suggestions for future research
- 6. LectureOutline • Vitamin D normal physiology and changes in CKD • Which vitamin D to measure at laboratory? Vitamin D level? • Vitamin D pleiotropic effect • Vitamin D use in CKD-MBD and vit D different forms/dosage • Hypomagnesemia and vitamin D deficiency in CKD • Suggestions for future research
- 8. In CKD
- 9. In CKD Nat Rev Nephrol. 2017 Jan;13(1):27-38
- 11. LectureOutline • Vitamin D normal physiology and changes in CKD • Which vitamin D to measure at laboratory? Vitamin D level? • Vitamin D pleiotropic effect • Vitamin D use in CKD-MBD and vit D different forms/dosage • Hypomagnesemia and vitamin D deficiency in CKD • Suggestions for future research
- 12. Whichvit D to measure at laboratory? J Bone Miner Res. 2007 Nov;22(11):1668-71 Measuredat laboratories
- 13. Phys Sportsmed. 2015 May;43(2):161-8
- 14. LectureOutline • Vitamin D normal physiology and changes in CKD • Which vitamin D to measure at laboratory? Vitamin D level? • Vitamin D pleiotropic effect • Vitamin D use in CKD-MBD and vit D different forms/dosage • Hypomagnesemia and vitamin D deficiency in CKD • Suggestions for future research
- 15. Int J Mol Sci. 2022 Aug 15;23(16):9135
- 16. Am J Kidney Dis. 2023 Jun 24:S0272-6386(23)00693-5 All-cause death in trials comparing vitamin D with placebo or no treatment 128 studies involving 11,270 adults with stage 3, 4, or 5 CKD, including kidney failure treated with dialysis
- 17. Am J Kidney Dis. 2023 Jun 24:S0272-6386(23)00693-5 128 studies involving 11,270 adults with stage 3, 4, or 5 CKD, including kidney failure treated with dialysis Cardiovascular death in trials comparing vitamin D with placebo or no treatment
- 18. Am J Kidney Dis. 2023 Jun 24:S0272-6386(23)00693-5 128 studies involving 11,270 adults with stage 3, 4, or 5 CKD, including kidney failure treated with dialysis Fracture outcomes in trials comparing vitamin D with placebo or no treatment
- 19. Am J Kidney Dis. 2023 Jun 24:S0272-6386(23)00693-5
- 20. Am J Kidney Dis. 2023 Jun 24:S0272-6386(23)00693-5
- 21. Calcif Tissue Int. 2021 Aug;109(2):157-178
- 22. LectureOutline • Vitamin D normal physiology and changes in CKD • Which vitamin D to measure at laboratory? Vitamin D level? • Vitamin D pleiotropic effect • Vitamin D use in CKD-MBD and vit D different forms/dosage • Hypomagnesemia and vitamin D deficiency in CKD • Suggestions for future research
- 23. Int J Mol Sci. 2022 Aug 15;23(16):9135
- 24. Am J Kidney Dis. 2023 Jun 24:S0272-6386(23)00693-5 128 studies involving 11,270 adults with stage 3, 4, or 5 CKD, including kidney failure treated with dialysis Fracture outcomes in trials comparing vitamin D with placebo or no treatment
- 25. Am J Kidney Dis. 2023 Jun 24:S0272-6386(23)00693-5
- 26. In CKD Calcidiolreplacement inCKD (cholecalciferolD3, ergocalciferolD2)
- 28. The decision of whether to measure, when to measure, how often, and to what target level needs to be individualized.
- 30. Correction of vitamin D deficiency – Protocol 1 Calcif Tissue Int. 2021 Aug;109(2):157-178
- 31. Calcif Tissue Int. 2021 Aug;109(2):157-178 Correction of vitamin D deficiency – Protocol 2
- 32. Calcif Tissue Int. 2021 Aug;109(2):157-178 Stopvit D supplementation if there is hypercalcemia
- 33. Calcif Tissue Int. 2021 Aug;109(2):157-178 Stopvit D supplementation if there is lowPTH
- 34. In CKD Calcidiolreplacement inCKD (cholecalciferolD3, ergocalciferolD2) Calcitriolor analogue replacementin CKD
- 35. Calcitriolor analogue replacementin CKD Clin J Am Soc Nephrol.2010 Mar;5(3):512-8 Alfacalcidol and doxercalciferol
- 36. Clin J Am Soc Nephrol.2010 Mar;5(3):512-8
- 37. Clin J Am Soc Nephrol.2010 Mar;5(3):512-8
- 38. Clin J Am Soc Nephrol.2010 Mar;5(3):512-8
- 39. Archives of Osteoporosis(2020) 15: 182
- 41. LectureOutline • Vitamin D normal physiology and changes in CKD • Which vitamin D to measure at laboratory? Vitamin D level? • Vitamin D pleiotropic effect • Vitamin D use in CKD-MBD and vit D different forms/dosage • Hypomagnesemia and vitamin D deficiency in CKD • Suggestions for future research
- 43. Lecture Outline • Vitamin D normal physiology and changes in CKD • Which vitamin D to measure at laboratory? Vitamin D level? • Vitamin D pleiotropic effect • Vitamin D use in CKD-MBD and vit D different forms/dosage • Hypomagnesemia and vitamin D deficiency in CKD • Suggestions for future research
- 44. Am J Kidney Dis. 2023 Sep 16:S0272-6386(23)00740-0