This document summarizes the work of the Subcommittee on Vaccines and Drug Development for the 32nd WHO South-East Asia Advisory Committee on Health Research. It discusses vaccine production, drug discovery centers, clinical trials, pharmacovigilance centers, drug development from traditional medicine, and efforts to harmonize drug regulations in the region. Key areas covered include the status of vaccine and drug research in India, Thailand, Bangladesh, and Indonesia. Challenges around human resources, facilities, and licensing drugs early are also noted.