Ree Dolly is a strong-willed young woman who is caring for her sick mother and younger brothers while searching desperately for her father, Jessup Dolly, who skipped bail. Jessup is a meth addict and dealer who has caused turmoil for the family. Ree distrusts men due to her father's actions and cares for her friend Gail, with whom she has lesbian tendencies. Through her determination to find her father, Ree hopes to escape her painful situation and join the Army. Other characters include Ree's meth-cooking uncle Teardrop, her friends and neighbors who variously help or hinder her search, and her abusive extended family members.