The WHO investment round aims to secure $7.1 billion through voluntary contributions to fund the General Programme of Work (GPW) 2025–2028, addressing current funding challenges and operational inefficiencies. It encourages member states, partners, and philanthropies to make pledges at various high-level events throughout the year to ensure predictable and flexible funding. Key messages highlight that a fully funded WHO could save over 40 million lives and generate significant returns on investment.