Vaccine-preventable Diseases and Immunization programme
Division of country health programmes
Data as of 02 March 2021
Measles and rubella monthly update—
WHO European Region
www.euro.who.int
Measles
Updates including 2021
2
3
Measles cases—WHO European Region,
February 2020–January 2021
Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city
or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2021. All rights reserved.
Top 10 countries
Country Cases
Uzbekistan 3341
Kazakhstan 2078
Russian Federation 916
Romania 642
Kyrgyzstan 549
Turkey 477
Bulgaria 151
France 151
Tajikistan 111
Ukraine 100
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
(1 country*)
*Montenegro submitted the last report for December 2019
4
Measles incidence per million population—
WHO European Region, February 2020–January 2021
Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city
or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2021. All rights reserved.
Top 10 countries
Country Incidence
Kazakhstan 110.67
Uzbekistan 99.82
Kyrgyzstan 84.15
Romania 33.37
Bulgaria 21.73
Tajikistan 11.64
Russian Federation 6.28
Turkey 5.66
Malta 4.53
Ireland 3.85
Population source: United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2019 Revision.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
(1 country*)
* Montenegro submitted the last report for December 2019
100
111
151
151
477
549
642
916
2078
3341
0 500 1000 1500 2000 2500 3000 3500 4000
Ukraine
Tajikistan
France
Bulgaria
Turkey
Kyrgyzstan
Romania
Russian Federation
Kazakhstan
Uzbekistan
Number of cases
5
Ten countries with the highest numbers of measles cases—
WHO European Region, February 2020–January 2021
Out of 8883 measles cases reported for February 2020 to January
2021, 8516 (96%) cases were reported by these 10 countries.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
6
Measles cases by month—WHO European Region,
2019–January 2021
Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
0
2000
4000
6000
8000
10000
12000
14000
16000
18000
20000
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
2019
(n=104442)
2020
(n=12198)
2021
(n=9)
Number
of
cases
Month
Lab confirmed Epi linked Clinically compatible
7
Measles genotypes by week of sample collection—
WHO European Region, week 5, 2018 to week 4, 2021
0
20
40
60
80
100
120
140
160
180
200
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
1
2
3
4
2018 2019 2020 2021
Number
of
sequences
reported
Week of sample collection
H1 D4 D9 B3 D8 C2
2018 2019 2020
Data source: WHO measles nucleotide surveillance online database (MeaNS) data as of 02 March 2021
2021
Measles
Latest update for 2020
8
9
Measles cases—WHO European Region, 2020
Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city
or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2021. All rights reserved.
Top 10 countries
Country Cases
Uzbekistan 4053
Kazakhstan 3269
Russian Federation 1100
Romania 976
Kyrgyzstan7 708
Turkey7 611
Bulgaria 245
France 240
Ukraine 211
Tajikistan 168
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
(1 country*)
* Montenegro submitted the last report for December 2019
10
Measles incidence per million population—
WHO European Region, 2020
Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city
or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2021. All rights reserved.
Top 10 countries
Country Incidence
Kazakhstan 176.21
Uzbekistan 122.89
Kyrgyzstan 110.35
Romania 50.40
Bulgaria 35.00
Tajikistan 18.02
Russian Federation 7.54
Turkey 7.32
Belgium 5.20
Georgia 5.00
Population source: United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2019 Revision.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
(1 country*)
* Montenegro submitted the last report for December 2019
11
Ten countries with the highest numbers of measles cases—
WHO European Region, 2020
168
211
240
245
611
708
976
1100
3269
4053
0 500 1000 1500 2000 2500 3000 3500 4000 4500
Tajikistan
Ukraine
France
Bulgaria
Turkey
Kyrgyzstan
Romania
Russian Federation
Kazakhstan
Uzbekistan
Number of cases
Out of 12 198 measles cases reported for 2020, 11 581 (95%) cases were
reported by these 10 countries.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
12
Measles cases by month—WHO European Region,
2018–2020
0
2000
4000
6000
8000
10000
12000
14000
16000
18000
20000
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
2018
(n=88693)
2019
(n=104442)
2020
(n=12198)
Number
of
cases
Month
Lab confirmed Epi linked Clinically compatible
Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
13
Measles cases and incidence by age group* and vaccination
status—WHO European Region, 2020
*Age was unknown for 34 cases.
Population source: United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2019 Revision.
390
71
17 12 9 9 3
0
50
100
150
200
250
300
350
400
450
0
500
1000
1500
2000
2500
3000
3500
4000
4500
<1
(n=4210)
1–4
(n=3201)
5–9
(n=1010)
10–14
(n=650)
15–19
(n=463)
20–29
(n=1061)
30+
(n=1569)
Incidence
per
million
population
Number
of
cases
Age group (years)
0 dose 1 dose 2+ doses Unknown Incidence
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
30604
33254
26788
32857
18869
28413
5273
25872
88693
104442
12198
93 94 95 95 94 94 93
95 95 96
80
82 83
89 89 89 88
90 91 91
0
20
40
60
80
100
2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
0
20000
40000
60000
80000
100000
120000
%
Coverage
Year
Number
of
cases
Measles cases MCV1 coverage MCV2 coverage
14
Measles cases, MCV1 and MCV2 coverage by year—
WHO European Region, 2010–2020
Data source: 1) Measles cases – monthly aggregated and case-based data reported by Member States to WHO/Europe or via ECDC/TESSy as of 02 March 2021.
2) MCV1 and MCV2 coverage - WHO/UNICEF Estimates of National Immunization Coverage (WUENIC) as of 15 July 2020.
MCV1: first dose of measles-containing vaccine
MCV2: second dose of measles-containing vaccine
Rubella
Updates including 2021
15
16
Five countries with the highest numbers of rubella cases—
WHO European Region, February 2020–January 2021
6
11
17
26
68
0 10 20 30 40 50 60 70 80
Italy
Turkey
Germany
Ukraine
Poland
Number of cases
Out of 140 rubella cases reported for February 2020 to January
2021, 128 (91%) cases were reported by these 5 countries.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
17
Rubella cases by month—WHO European Region,
2019–January 2021
0
20
40
60
80
100
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
2019
(n=630)
2020
(n=188)
2021
(n=8)
Number
of
cases
Month
Lab confirmed Epi linked Clinically compatible
Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
Rubella
Latest update for 2020
18
19
Five countries with the highest numbers of rubella cases—
WHO European Region, 2020
15
16
17
27
96
0 20 40 60 80 100 120
Turkey
Italy
Germany
Ukraine
Poland
Number of cases
Out of 188 rubella cases reported for 2020, 171 (91%) cases
were reported by these 5 countries.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
20
Rubella cases by month—WHO European Region,
2018–2020
0
20
40
60
80
100
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
2018
(n=839)
2019
(n=630)
2020
(n=188)
Number
of
cases
Month
Lab confirmed Epi linked Clinically compatible
Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
21
Links to measles and rubella information
• WHO EpiData
www.euro.who.int/en/health-topics/disease-prevention/vaccines-and-immunization/publications/surveillance-and-data/who-epidata
• Country slides for measles and rubella
www.who.int/immunization/monitoring_surveillance/burden/vpd/surveillance_type/active/measles_monthlydata/en/
• WHO EpiBrief
www.euro.who.int/en/health-topics/disease-prevention/vaccines-and-immunization/publications/surveillance-and-data/who-epibrief

WHO EpiData (data as of 02 March 2021)

  • 1.
    Vaccine-preventable Diseases andImmunization programme Division of country health programmes Data as of 02 March 2021 Measles and rubella monthly update— WHO European Region www.euro.who.int
  • 2.
  • 3.
    3 Measles cases—WHO EuropeanRegion, February 2020–January 2021 Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2021. All rights reserved. Top 10 countries Country Cases Uzbekistan 3341 Kazakhstan 2078 Russian Federation 916 Romania 642 Kyrgyzstan 549 Turkey 477 Bulgaria 151 France 151 Tajikistan 111 Ukraine 100 Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021 (1 country*) *Montenegro submitted the last report for December 2019
  • 4.
    4 Measles incidence permillion population— WHO European Region, February 2020–January 2021 Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2021. All rights reserved. Top 10 countries Country Incidence Kazakhstan 110.67 Uzbekistan 99.82 Kyrgyzstan 84.15 Romania 33.37 Bulgaria 21.73 Tajikistan 11.64 Russian Federation 6.28 Turkey 5.66 Malta 4.53 Ireland 3.85 Population source: United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2019 Revision. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021 (1 country*) * Montenegro submitted the last report for December 2019
  • 5.
    100 111 151 151 477 549 642 916 2078 3341 0 500 10001500 2000 2500 3000 3500 4000 Ukraine Tajikistan France Bulgaria Turkey Kyrgyzstan Romania Russian Federation Kazakhstan Uzbekistan Number of cases 5 Ten countries with the highest numbers of measles cases— WHO European Region, February 2020–January 2021 Out of 8883 measles cases reported for February 2020 to January 2021, 8516 (96%) cases were reported by these 10 countries. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
  • 6.
    6 Measles cases bymonth—WHO European Region, 2019–January 2021 Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021 0 2000 4000 6000 8000 10000 12000 14000 16000 18000 20000 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2019 (n=104442) 2020 (n=12198) 2021 (n=9) Number of cases Month Lab confirmed Epi linked Clinically compatible
  • 7.
    7 Measles genotypes byweek of sample collection— WHO European Region, week 5, 2018 to week 4, 2021 0 20 40 60 80 100 120 140 160 180 200 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 2018 2019 2020 2021 Number of sequences reported Week of sample collection H1 D4 D9 B3 D8 C2 2018 2019 2020 Data source: WHO measles nucleotide surveillance online database (MeaNS) data as of 02 March 2021 2021
  • 8.
  • 9.
    9 Measles cases—WHO EuropeanRegion, 2020 Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2021. All rights reserved. Top 10 countries Country Cases Uzbekistan 4053 Kazakhstan 3269 Russian Federation 1100 Romania 976 Kyrgyzstan7 708 Turkey7 611 Bulgaria 245 France 240 Ukraine 211 Tajikistan 168 Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021 (1 country*) * Montenegro submitted the last report for December 2019
  • 10.
    10 Measles incidence permillion population— WHO European Region, 2020 Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2021. All rights reserved. Top 10 countries Country Incidence Kazakhstan 176.21 Uzbekistan 122.89 Kyrgyzstan 110.35 Romania 50.40 Bulgaria 35.00 Tajikistan 18.02 Russian Federation 7.54 Turkey 7.32 Belgium 5.20 Georgia 5.00 Population source: United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2019 Revision. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021 (1 country*) * Montenegro submitted the last report for December 2019
  • 11.
    11 Ten countries withthe highest numbers of measles cases— WHO European Region, 2020 168 211 240 245 611 708 976 1100 3269 4053 0 500 1000 1500 2000 2500 3000 3500 4000 4500 Tajikistan Ukraine France Bulgaria Turkey Kyrgyzstan Romania Russian Federation Kazakhstan Uzbekistan Number of cases Out of 12 198 measles cases reported for 2020, 11 581 (95%) cases were reported by these 10 countries. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
  • 12.
    12 Measles cases bymonth—WHO European Region, 2018–2020 0 2000 4000 6000 8000 10000 12000 14000 16000 18000 20000 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2018 (n=88693) 2019 (n=104442) 2020 (n=12198) Number of cases Month Lab confirmed Epi linked Clinically compatible Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
  • 13.
    13 Measles cases andincidence by age group* and vaccination status—WHO European Region, 2020 *Age was unknown for 34 cases. Population source: United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2019 Revision. 390 71 17 12 9 9 3 0 50 100 150 200 250 300 350 400 450 0 500 1000 1500 2000 2500 3000 3500 4000 4500 <1 (n=4210) 1–4 (n=3201) 5–9 (n=1010) 10–14 (n=650) 15–19 (n=463) 20–29 (n=1061) 30+ (n=1569) Incidence per million population Number of cases Age group (years) 0 dose 1 dose 2+ doses Unknown Incidence Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
  • 14.
    30604 33254 26788 32857 18869 28413 5273 25872 88693 104442 12198 93 94 9595 94 94 93 95 95 96 80 82 83 89 89 89 88 90 91 91 0 20 40 60 80 100 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 0 20000 40000 60000 80000 100000 120000 % Coverage Year Number of cases Measles cases MCV1 coverage MCV2 coverage 14 Measles cases, MCV1 and MCV2 coverage by year— WHO European Region, 2010–2020 Data source: 1) Measles cases – monthly aggregated and case-based data reported by Member States to WHO/Europe or via ECDC/TESSy as of 02 March 2021. 2) MCV1 and MCV2 coverage - WHO/UNICEF Estimates of National Immunization Coverage (WUENIC) as of 15 July 2020. MCV1: first dose of measles-containing vaccine MCV2: second dose of measles-containing vaccine
  • 15.
  • 16.
    16 Five countries withthe highest numbers of rubella cases— WHO European Region, February 2020–January 2021 6 11 17 26 68 0 10 20 30 40 50 60 70 80 Italy Turkey Germany Ukraine Poland Number of cases Out of 140 rubella cases reported for February 2020 to January 2021, 128 (91%) cases were reported by these 5 countries. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
  • 17.
    17 Rubella cases bymonth—WHO European Region, 2019–January 2021 0 20 40 60 80 100 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2019 (n=630) 2020 (n=188) 2021 (n=8) Number of cases Month Lab confirmed Epi linked Clinically compatible Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
  • 18.
  • 19.
    19 Five countries withthe highest numbers of rubella cases— WHO European Region, 2020 15 16 17 27 96 0 20 40 60 80 100 120 Turkey Italy Germany Ukraine Poland Number of cases Out of 188 rubella cases reported for 2020, 171 (91%) cases were reported by these 5 countries. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
  • 20.
    20 Rubella cases bymonth—WHO European Region, 2018–2020 0 20 40 60 80 100 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2018 (n=839) 2019 (n=630) 2020 (n=188) Number of cases Month Lab confirmed Epi linked Clinically compatible Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems. Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2021
  • 21.
    21 Links to measlesand rubella information • WHO EpiData www.euro.who.int/en/health-topics/disease-prevention/vaccines-and-immunization/publications/surveillance-and-data/who-epidata • Country slides for measles and rubella www.who.int/immunization/monitoring_surveillance/burden/vpd/surveillance_type/active/measles_monthlydata/en/ • WHO EpiBrief www.euro.who.int/en/health-topics/disease-prevention/vaccines-and-immunization/publications/surveillance-and-data/who-epibrief