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White blood cells are produced in bone marrow and circulate in blood and lymph. Four main
kinds of white blood cells are involved in the immune response. Macrophages consume
pathogens and infected cells. (10) attack and kill infected cells. (11) label invaders for later
destruction by macrophages. (12) activate both cytotoxic T cells and B cells. An infected body
cell will display of an invader on its surface. These are substances that trigger an immune
response. In an immune response, B cells divide and develop into (14) , which release special
defensive proteins into the blood. These special proteins are called (15)

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