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Which of the following would you predict to result from a mutation in TLR4 that prevents
binding to LPS? Select ALL that apply Increased susceptibility to infection with gram-negative
bacteria Decreased susceptibility to septic shock Increased susceptibility to infection with gram-
positive bacteria Tighter binding between bacteria and macrophages Increased phagocytosis
Which of the following would you predict to result from a mutation in TLR4 that prevents
binding to LPS? Select ALL that apply Increased susceptibility to infection with gram-negative
bacteria Decreased susceptibility to septic shock Increased susceptibility to infection with gram-
positive bacteria Tighter binding between bacteria and macrophages Increased phagocytosis

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