Cannabis and CBD for you liver, or no, read this https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us

1. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 2/11
CANNABIS FOR LIVER ISSUES
How Do Cannabis and CBD Affect Your
Liver - What the Latest Studies are
Telling Us
Can cannabis and CBD help with liver issues and past liver damage?
Posted by:
Laurel Leaf, today at 12:00am
 Edit Article (https://cannabis.net/mycannabis/c-blog-entry/update/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us)
 Article List (https://cannabis.net/mycannabis/c-blog)

2. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 3/11
Cannabis has a vast array of therapeutic potential. The cannabinoids in the plant are anti-carcinogenic,
anti-inflammatory, and anti-bacterial. Studies have shown that cannabis-derived medications help with
weight loss, stress and pain relief, improving lung capacity, among other benefits.
In recent decades, extensive research has been conducted to determine the therapeutic potential of
cannabis for liver conditions and the level of receptivity of localized receptors in the liver to cannabinoids.
In this post, we'll explore and break down the available research showing the relative effects of medical
cannabis on liver diseases (https://cannabis.net/blog/medical/cannabis-reduces-liver-disease-and-
cirrhosis-risk-among-hepatitis-c-patients) and whether or not cannabis can cause adverse effects on the
liver.
The Purpose of the Liver
The liver is located on the right side of the body, just beneath the diaphragm and above the gallbladder.
An average-sized adult liver weighs 1.4 kg. It has two unequally sized lobes known as the right lobe and the
left lobe. Of the two, the right lobe is larger. Both are connected by connective tissue, which keeps the
organ attached to the abdominal wall.
This singular organ plays a vital role in sustaining the body, one of which is excretion. It filters out the good
and valuable components of ingested materials and passes the rest on to be excreted from the body. It is
regarded as a natural detoxifier. The most important part of the liver is the portal vein. This vein
transports the original blood vessel from the digestive organs to the liver for sorting through. The liver
filters out the harmful materials and sends off the blood, containing only suitable materials. The liver
produces bile (to break down fat compounds).
Vitamin K is one of the essential vitamins the liver needs to produce protein juices used for clotting in case
of injuries.
Common Liver Conditions
Like other vital human organs, there's only so much a liver can handle. It does a lot of work processing
natural and synthetic materials, some of which are drugs. A study pointed out that not all livers have
evolved enough to process synthetic materials. This is why they break down after encountering such
materials continuously. Not all liver conditions are severe, but some could be fatal.

3. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 4/11
Some common liver conditions include fibrosis, hepatitis, fatty liver disease, and cirrhosis. The primary
cause of most of these diseases is a poor and unhealthy lifestyle. Alcoholism and excessive drug use are
two leading causes of liver conditions, followed closely by obesity and other unchecked or untreated
ailments. For example, cirrhosis occurs when fibrosis is either undetected or untreated. So many things
could go wrong in the liver because every ingested material goes through it. The liver is scarred by
excessive drugs, alcohol, and unhealthy meals.
Treating And Managing Liver Conditions
Often, the liver can repair its cells as some of the conditions are reversible. In advanced cases like fibrosis,
it is managed with healthy living and medications. Leaving a liver disease untreated could cause it to
degenerate into worse conditions like liver failure and even death. If the liver has a bad case of scar tissue
buildup, the patient's only option could be a liver transplant (which is difficult and costly to find).
The Liver and Cannabis
The future role of cannabinoids in maintaining liver function is being investigated around the world. While
it is impossible to draw conclusions now, it is not out of place to state that they have sound potential.
Here is a look at the level of research carried out so far.
Cannabis and Fibrosis
The endocannabinoid system is made up of receptors (https://cannabis.net/blog/medical/amazing-facts-
about-your-endocannabinoid-system). The most important ones are CB1 and CB2. These receptors occur
in the body along with enzymes in relative amounts. The body also produces natural cannabinoids and
endocannabinoids. These compounds ensure that all body functions are regulated and normal. When
cannabis is ingested, the cannabinoids interact with the ECS receptors to produce a similar effect as
endocannabinoids.

4. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 5/11
There are limited CB1 and CB2 receptors in the liver, but there are higher amounts in diseased livers than
in healthy ones. Scientists suggest that these receptors are vital to the regeneration process of scarred
tissues in the organ. Parfieniuk and Flisaik explained this complex process in a 2008 study. The scientists
proposed that the receptors have opposing roles. CB1 functions as a profibrogenic and proinflammatory
compound, while CB2 opposes these functions.
For patients suffering from fibrosis, CB1 has the potential to worsen the condition, while CB2 can be used
to manage it. Only cannabis plants that can activate the CB2 receptor can be used to treat liver conditions.
In 2011, further studies showed that CB2 receptors have the potential to kill malignant cells in the liver and
reduce the buildup of scarred tissue. If the ECS is properly manipulated, CBD-derived cannabis
medications can be helpful for fibrosis.
Cannabis and Hepatitis
Hepatitis is gradually rising to be one of the major causes of fatalities around the world. It is a physically-
taxing ailment that is extremely difficult to treat, and it has no cure. The disease can induce an immune-
modulated liver condition. The available research on this was conducted on mice, and the information
cannot be used for humans.
In the rodents, the scientists observed a reduction in cytokine levels by anandamides. When cannabis is
ingested in humans, it makes many anandamide compounds available to receptors by inhibiting FAAH.
Still, it's unclear whether the cytokine levels in humans would be reduced due to this.
Final Note: The Impact of Cannabis On The Liver
The effects of cannabis on the liver are still unclear. Scientists have not been able to establish whether or
not the drug is bad or good. However, they have emphasized that those with liver conditions have no
business smoking cannabis, and should consume it orally. More research is needed to explain the in-depth
relationship between cannabinoids and the liver, primarily THC and CBD.
It is important to note that in human subjects, CBD interacts with ingested medications
(https://cannabis.net/blog/medical/can-i-take-cbd-with-other-medications). It inhibits the production of the
liver enzyme cytochrome P450 (used to break down drugs and foreign materials). Before consuming CBD-
based medicine, consult a medical professional. This way, you'll be sure the medication is doing more
good than harm.
CANNABIS AND LIVER DISEASE, READ MORE...

5. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 6/11
(https://cannabis.net/blog/medical/cannabis-for-cirrhosis-
and-liver-disease)
WHAT CAN CANNABIS DO FOR CIRRHOSIS, READ MORE! (https://cannabis.net/blog/medical/cannabis-
for-cirrhosis-and-liver-disease)
OR..
(https://cannabis.net/blog/medical/top-cannabis-strains-
for-liver-disease)
WHAT MARIJUANA STRAINS HELP WITH LIVER DISEASE? (https://cannabis.net/blog/medical/top-
cannabis-strains-for-liver-disease)
What did you think?
Keep reading... click here
(https://cannabis.net/blog)
0 0 0 0 0 0

6. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 7/11
Leave a Comment:
Submit
What are your thoughts?
HOW TO (HTTPS://CANNABIS.NET/BLOG/HOW-TO) LOCATIONS (HTTPS://CANNABIS.NET/BLOG/LOCATIONS)
DABS (HTTPS://CANNABIS.NET/BLOG/DABS) FUNNY (HTTPS://CANNABIS.NET/BLOG/FUNNY)
STRAINS (HTTPS://CANNABIS.NET/BLOG/STRAINS) B2B (HTTPS://CANNABIS.NET/BLOG/B2B)
TECHNOLOGY (HTTPS://CANNABIS.NET/BLOG/TECHNOLOGY) HISTORY (HTTPS://CANNABIS.NET/BLOG/HISTORY)
VOTE (HTTPS://CANNABIS.NET/BLOG/VOTE) RECIPES (HTTPS://CANNABIS.NET/BLOG/RECIPES)
OPINION (HTTPS://CANNABIS.NET/BLOG/OPINION) VIDEOS (HTTPS://CANNABIS.NET/BLOG/VIDEOS)
SPORTS (HTTPS://CANNABIS.NET/BLOG/SPORTS) EVENTS (HTTPS://CANNABIS.NET/BLOG/EVENTS)
MEDICAL (HTTPS://CANNABIS.NET/BLOG/MEDICAL) SMOKE (HTTPS://CANNABIS.NET/BLOG/SMOKE)
VAPING (HTTPS://CANNABIS.NET/BLOG/VAPING)
PERSONAL STORY (HTTPS://CANNABIS.NET/BLOG/PERSONAL-STORY)
INTERVIEW (HTTPS://CANNABIS.NET/BLOG/INTERVIEW) SEXY (HTTPS://CANNABIS.NET/BLOG/SEXY)
NEWS (HTTPS://CANNABIS.NET/BLOG/NEWS)
CATEGORIES
FEATURED

7. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 8/11
(https://cannabis.net/blog/news/3-facts-you-should-know-about-the-changes-to-cannabis-legalization-in-massachusetts)
NEWS
3 Facts You Should Know About The Changes To Cannabis Legalization In Massachusetts
In the new bill, the decision to ban cannabis shops would be based on how a certain town voted on the cannabis ballot question during the
elections last November 2016.

8. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 9/11
(https://cannabis.net/blog/recipes/how-to-make-delicious-cannabisinfused-popsicles)
RECIPES
How to Make Delicious Cannabis-Infused Popsicles
This offers a wonderful way to get over the heat, can be enjoyed anywhere and is very easy to make in the comfort of your own kitchen.
Popsicles are loved by many with the beauty of flavors and color that they offer and the making process is very simple and straightforward.

9. 1/18/22, 3:35 PM How Do Cannabis and CBD Affect Your Liver - What the Latest Studies are Telling Us
https://cannabis.net/blog/medical/how-do-cannabis-and-cbd-affect-your-liver-what-the-latest-studies-are-telling-us 10/11
(https://cannabis.net/blog/b2b/will-making-all-cannabis-taxfree-get-people-to-convert-from-the-illicit-market-to-the-legal-mar)
B2B
Will Making All Cannabis Tax-Free Get People to Convert from the Illicit Market to the Legal Market?
Mandelman concluded his statement by disclosing that by the fourth quarter of 2022, a new set of recommendations for tax rates would be
presented to the board. In addition to this, the cannabis industry might be restructured to help the industry retain its edge over the illegal
industry.