This document summarizes an active adult community called Villaggio located in Palm Beach County, Florida. It features 538 single family homes surrounding lakes and golf courses. The community has two clubhouses totaling over 48,000 square feet that include resort style amenities like pools, fitness centers, card rooms, and more. Home prices start in the mid $300,000s and the community offers both furnished and unfurnished single family home options.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?
Villaggio Active Adult Community
1. Palm Beach County’s Premier
Active-Adult Community
S I n G L e - FA m I Ly H O m e S F rO m t H e m I d $ 3 0 0 ’ S .
1 V I L L AG G I O
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2. Two Fabulous Clubhouses Enjoy Resort-Style Living!
Villaggio is an exclusive and intimate active-adult gated community of only 538 homes surrounded
by lakes, golf courses and plush landscaping. Set on over 11 acres of recreational space and complete
with a Full Time Activities Director are the community’s two spectacular clubhouses.
35,000 Sq. Ft. SOCIAL CLuB 13,000 Sq. Ft. FItneSS CLuB
FeAturInG: FeAturInG:
Resort-Style Lap Pool • Arts & Crafts Center Fitness Center • Indoor Heated Pool & Separate Spa
3 Card Rooms • Putting Green • Billiards Room Aerobics Studio • Hair & Nail Salon • Tennis
Deli/Café • Grand Hall • And MUCH MORE! Racquetball Court • And MUCH MORE!
SOCIAL CLuB — Over 35,000 Sq. Ft.
Huge Pool deck for
Separate Covered Lanai
Social Gatherings
with restrooms
Gazebos Overlooking Spa
the Lakes
Covered Porticos
resort-Style Heated
Lap Pool
Putting Green
Grand Hall with raised
Stage and dance Floor Billiards room
and Box Office for
Shows and Performances,
exquisite Lobby
Catering Kitchen
movies and more!
Lounge & deli/Café
Arts & Crafts
Center with Kiln
3 Card rooms/
meeting room
Business and Wireless
Internet Center
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3. FItneSS CLuB — Over 13,000 Sq. Ft.
Jogging Path
Indoor Spa
2,100 square foot Fitness
room featuring State-of-the-
Indoor Heated Pool for Art Cardiovascular and Weight
year-round use training equipment
Locker rooms
Indoor racquetball Court
Separate Aerobic,
dance Studio
Steam rooms
with Showers
tennis Pro Shop
Full Service Hair
and nail Salon
6 tennis Courts
massage and
Bocci Gazebo
Therapy room
What Our Homeowners Are Saying...
“Villaggio’s facilities are more than we could
“We immediately fell in love with the
community and the lifestyle. You offered have asked for in any community. There are
it all, a beautiful home, a charming activities here that could keep a person busy
community and the fabulous active-adult endlessly. And I thought retirement would
lifestyle. Gail and I have never be boring. Our special thanks to you
been happier.” for making our dreams a reality.”
Andrew J. Steinfeld, manny & Harriet Blum
Villaggio Homeowner Villaggio Homeowners
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4. Grand Finale
The Villaggio Community
e
G
F
71
92
1
2
4
5
48
33
13
15
35
23 32
Mov
21
Fu
R
13
12
11
12
e
3 Sold
4 Sold
5 Sold
7
6 Sold
Model Row
Site Plan
Furnished Model
Move-In Ready Hom Row Homes
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5. DaVinci Collection
Novara
3 Bedroom, 2 Bath
a/c sq. ft. 2,053 • total sq. ft. 2,724
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6. DaVinci Collection
Modena
3 Bedroom, 2½ Bath
a/c sq. ft. 2,230 • total sq. ft. 2,917
5 V I L L AG G I O
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7. DaVinci Collection
Capri
2 Bedroom, Den, 2 Bath
a/c sq. ft. 2,073 • total sq. ft. 2,750
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8. DaVinci Collection
Portofino
3 Bedroom, 2 Bath
a/c sq. ft. 1,882 • total sq. ft. 2,606
7 V I L L AG G I O
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9. Michelangelo Collection
Pisa
3 Bedroom, 2½ Bath
a/c sq. ft. 2,463 • total sq. ft. 3,184
8 V I L L AG G I O
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10. Michelangelo Collection
Perugia
3 Bedroom, 2½ Bath
a/c sq. ft. 2,534 • total sq. ft. 3,250
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11. Michelangelo Collection
Riviera
3 Bedroom, 2½ Bath
a/c sq. ft. 2,740 • total sq. ft. 3,570
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12. Modena
Riviera
Capri
Riviera
Modena
Modena
Capri
Gorgeous Entry
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13. From I-95 and the Florida turnpike: Exit Boynton Beach
BOyntOn BeACH
Boulevard and proceed west to Lyons Road. Make a right on
Lyons Road (North) and proceed approximately 3 miles to
Hypoluxo Road. At Hypoluxo Road intersection make a right
and proceed approximately 1 mile to Villaggio Gate House on
the left. Once thru the gates make immediate left turn onto
Via Avellino. Proceed to Sales Center and Model Row at the
end of Via Avellino (on the left).
US 441/SR7
Floorplans are for illustrative and conceptual purposes. Floorplans may not be to scale. All measurements are approximate. Square footage is measured
from the outside of the exterior wall. Dimensions, specifications and features, subject to change without notice.
Call and Visit today! 561-433-4933