The document lists various medical conditions, diseases, infections, medical devices, diagnostic equipment, and other healthcare categories. It then discusses healthcare development and financing cycles, and outlines how a healthcare investment marketplace could showcase investment opportunities, reduce financing risk, provide additional carried interest for investors, increase transaction certainty and exit opportunities, and ultimately achieve superior returns.
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Value to lead investor
1. Diabetic Nephropathy
Diabetic Retinopathy
Hypercholesterolemia
Oral Mucositis
Gout
Acute Lymphocytic Leukemia
Bone Metastasis
Brain Cancer
Breast Cancer
Cervical Cancer
Chronic Lymphocytic Leukemia
Endometrial Cancer
Ewing Sarcoma
Gastric Cancer
Gastrointestinal Stromal Tumors
Head And Neck Cancer
Hodgkin Lymphoma
Kidney Cancer
Liver Cancer
Malignant Mesothelioma
Medullary Thyroid Cancer
Melanoma
Multiple Myeloma
Non-Hodgkin Lymphoma
Non-Small Cell Lung Cancer
Ovarian Cancer
Pancreatic Cancer
Testicular Cancer
Thyroid Cancer
Age Related Macular Degeneration
Keratoconjunctivitis sicca (Dry Eye)
Retinal Vein Occlusion
Acute Respiratory Distress
Syndrome
Sepsis
Staphylococcal Infections
Acute Coronary Syndrome
Angina Pectoris
Atrial Fibrillation
Coronary Artery Disease (CAD)
Critical Limb Ischemia
Hypertension
Pulmonary Arterial Hypertension
Acute Pain
Anxiety Disorders
Chronic Pain
Dementia
Diabetic Neuropathy
Obsessive-Compulsive Disorder
Osteoarthritis Pain
Parkinson's Disease
Post-Traumatic Stress Disorder
Restless Legs Syndrome
Schizophrenia
Traumatic Brain Injury
Liver Cirrhosis
Childhood Enuresis
Growth Hormone Disorders
Hyperparathyroidism
Hyperthyroidism
Guillain-Barre Syndrome
Cytomegalovirus
Fungal Infections
Gram-Negative Bacterial Infections
H1N1 Infection
Herpes Zoster
HIV-1 Infection
Human Papillomavirus Infections
Staphylococcus Aureus (MRSA)
Cardiovascular Devices
Prosthetic Heart Valve
Peripheral Vascular Devices
Cardiovascular Monitoring & Diagnostic Devices
Cardiovascular Surgery
Cardiac Rhythm Management
Cardiovascular Prosthetic Devices
Interventional Cardiology
Cardiac Assist Devices
Wound Care Management
Hospital Supplies
Syringes and Needles
Disposable Hospital & Surgical Supplies
Drug Delivery Devices
Inhalation Systems
Needle Free Injections
Infusion Systems
Diabetes Care Devices
Insulin Delivery & Glucose Monitoring
Ophthalmic Devices
Cataract Surgery Devices
Ophthalmic Diagnostic Equipment
Refractive Surgery Devices
ENT Devices
Hearing Implants
Diagnostic Devices
Electrosurgical Devices
Dental Equipment & Accessories
Diagnostic Imaging & MRI Systems
C/T Systems & Mammography Equipment
X-Ray & Ultrasound Systems
Nuclear Imaging Equipment
Contrast Media Injectors
Bone Densitometry
Anesthesia and Respiratory Devices
Anesthesia Machines & Disposables
Respiratory Devices & Disposables
Sleep Apnea Diagnostic Systems
Healthcare IT
Medical Imaging Information Systems
Nephrology and Urology Devices
Renal Dialysis Equipment
Orthopedic Devices
Orthobiologics & Arthroscopy
Joint Reconstruction
Trauma Fixation
Orthopedic Prosthetics
Cranium Maxillofacial Fixation (CMF)
Spinal Surgery
Endoscopy Devices & instruments
Rigid & Flexible Endoscope
In Vitro Diagnostics
Genetic Testing
Clinical Chemistry
Hematology
Immuno Chemistry
Infectious Immunology
Histology And Cytology
Patient Monitoring
Multiparameter Patient Monitoring
Micro-Electromechanical Systems
Non-invasive Blood Pressure Monitors
Neurology Devices
Neurostimulation Devices
Interventional Neurology
CSF Management
Neurosurgical Products
Radiosurgery
Value to the
Lead Investor
2. Healthcare’s Investment Marketplace
Discovery
Develop-
ment I
N
D
PhaseI
PhaseII
PhaseIII
N
D
A
Approval
Launch
Growth
Mature
Healthcare Development & Financing Cycle
IPO / Public MarketsVenture CapitalAngels / Founders Private Equity / M&A
SEED
EXIT
… E M E R G I N G G R O W T H C O M PA N I E S
… ‘ L E A D ’ I N V E S T O R S
… D I R E C T I N V E S T O R S
… S T R AT E G I C PA RT N E R S & B U Y E R S
T R A N S F O R M I N G H E A LT H C A R E C A P I TA L M A R K E T S
on behalf of…
3. Healthcare’s Investment Bank
HealthiosXchange
12,000 Investors
Across (10)
Asset Classes
in (37) Countries &
2,000 Strategics in
(46) Market sectors
“Seed-to-Exit”
Direct
Investment
NO
Adverse
Selection
Messaging
&
Notifications
Ratings &
Reviews
Rules-Based
Deal Flow
Prediction &
Sentiment Data
Proprietary
Events
(6,000)+
Growth
Companies
NO Fee
NO Carry
Shorter “Exit”
Horizons
Real-Time
Valuations &
Research
Less
Correlation
Reporting &
Communications
Zero
Un-Invested
Capital
SHOWCASING THE PORTFOLIO
REDUCED FINANCING RISK
ADDITIONAL CARRIED INTEREST
GREATER FINANCING & “EXIT”
CERTAINTY
SUPERIOR RETURNS
8. Healthcare’s Investment Bank
Greater Transaction Certainty & “Exit” Path
The actual
number of
months before
the next
transaction is 4.
We predicted 3.
The actual value of the next
transaction is $150 million
and we predicted $150
million.
9. Healthcare’s Investment Bank
Superior Returns
12,000 Investors
Across (10)
Asset Classes
in (37) Countries &
2,000 Strategics in
(46) Market sectors
“Seed-to-Exit”
Direct
Investment
NO
Adverse
Selection
Messaging
&
Notifications
Ratings &
Reviews
Rules-Based
Deal Flow
Prediction &
Sentiment Data
Proprietary
Events
(6,000)+
Growth
Companies
NO Fee
NO Carry
Shorter “Exit”
Horizons
Real-Time
Valuations &
Research
Less
Correlation
Reporting &
Communications
Zero
Un-Invested
Capital
SUPERIOR RETURNS
Editor's Notes
All-at-once, the global healthcare industry is the most complex, chaotic, compelling and dynamic market in the world.
A $3 trillion global industry, growing 16% annually, capitalizing itself $13.8 million at a time through more than 9,000 negotiated transactions in 6,000 companies into which, on average, $49 million of capital is deployed over 6.2 years, yielding a “Cash-on-Cash” returns of 4.1x and IRR’s of 22.1% while generating 81% liquidity on invested capital through 892 “Exit” events, of which 87% are M&A.
HealthiosXchange is the premier capital marketplace dedicated exclusively to the global healthcare industry. By aggregating 6,000 Emerging Growth healthcare companies in (37) countries together with 30,000 investors in (10) asset classes and 2,000 strategic partners representing (46) market sectors IN A SINGLE MARKET ENVIRONMENT, HealthiosXchange represents a universal capital markets experience perfectly reflective of the industry it serves. We intend to transform the manner in which capital is invested – and value is realized – throughout the global healthcare industry, by serving the needs of:
The most successful Lead Investors
HealthiosXchange believes that the cornerstone of the global healthcare capital markets is the “Lead” institutional investor: Venture Capital, Growth Equity and Private Equity firms. In the healthcare capital markets, the “Lead” investor plays a critically important role:
Screening deal flow
Selecting the opportunity
Performing due diligence
Pricing the investment
Negotiating the transaction
Overseeing management
Providing governance
Performance measurement & reporting
Managing financing and liquidity pathway
HealthiosXchange seeks to be the premier healthcare capital market in the world, by transforming the manner in which capital is invested – and value is realized – throughout the global healthcare industry. We intend to achieve this goal by assisting “Lead” investors to:
Showcase their portfolio
Reduce financing risk in their portfolio
Achieve superior investment returns
Extend the relationship of Lead investors with their own Limited Partners
Create greater financing and “Exit” certainty
HealthiosXchange provides every emerging growth healthcare company with its own customized profile to:
Perfect the Company’s positioning within their target market sector
Maximize awareness among its Peers within its target market
360-degree social and industry media exposure
Engage with prospective investors and strategic partners
Provide notifications and alerts to key relationships based on news flow
Benchmark success with exclusive valuation, capital flows and investment research
Report progress to “Friends”, “Followers”, investors, partners and buyers
For Lead investors, these capabilities permit them to manage their portfolio in the most consistent, transparent and efficient manner.
Listed on HealthiosXchange are more than 30,000 healthcare investors in (37 countries, segregated in (10) discrete asset classes, along with more than 2,000 strategic buyers in (46) market categories. Among the listed investors are:
3,700 Family Offices
2,100 Alternative Direct Investors
1,300 “Cross-Over” Investors
18,000 Registered Investment Advisors
137 Private Banks
212 Foreign Trusts
29 Sovereign Wealth Organizations
Through this global footprint, HealthiosXchange is building the most comprehensive universe of active healthcare investors in the world. This capital markets footprint represents and important resource for “Lead” investors to ensure continuous, efficient and cost effective access to capital for their entire healthcare portfolio.
55% of Limited Partners with fund investments in healthcare identified management fees as the principal motivation for a shift in investment strategies. In addition, investors cited better control of investments, greater transparency, and an opportunity to gain direct exposure to new industries.
60% of North American investors (and more than 40% of foreign investors) would pay higher carried interest in return for lower fund management fees.
HealthiosXchange is pioneering unique capital markets strategies and syndication techniques which permit Lead investors to deepen their relationships with the Limited Partner community. In certain transactions, it will be possible for “Lead” investors to earn carried interest on capital deployed directly alongside of their own in support of the financing needs of designated portfolio companies.
100% of investment returns in the global healthcare industry is generated by 23.7% of portfolio companies
There have been (4,393) M&A transactions completed in the global healthcare industry between 2003 and 2012. Of those transactions, 80% (or 3,514 deals) have been consummated by 56% (or 1,107) of the strategic buyers
The ratio of portfolio companies which attracted a minimum of $15 million in invested capital since 2009 to strategic buyer which has consummated a minimum of one M&A transaction during the same period = 20.3 to 1
Exits represent the culmination of the investment cycle: a time when buyers consolidate value, when investors realize return, and when entrepreneurs consummate their success.
Yet, throughout the emerging growth healthcare community, liquidity has become exceedingly difficult to achieve.
HealthiosXchange provides Lead investors with the resources to ensure greater transaction certainty and “Exit” pathways by:
Hosting exclusive online events, investment conferences, road shows and “Shark Tanks”
Trending & Activity Reports
Benchmarking the achievement of milestones and inflection points (v.s. Peers)
Exploiting proprietary capital markets tools, such as Matching, Targeting and Geo-Location
100% of investment returns in the global healthcare industry is generated by 23.7% of portfolio companies
There have been (4,393) M&A transactions completed in the global healthcare industry between 2003 and 2012. Of those transactions, 80% (or 3,514 deals) have been consummated by 56% (or 1,107) of the strategic buyers
The ratio of portfolio companies which attracted a minimum of $15 million in invested capital since 2009 to strategic buyer which has consummated a minimum of one M&A transaction during the same period = 20.3 to 1
Exits represent the culmination of the investment cycle: a time when buyers consolidate value, when investors realize return, and when entrepreneurs consummate their success.
Yet, throughout the emerging growth healthcare community, liquidity has become exceedingly difficult to achieve.
HealthiosXchange provides Lead investors with the resources to ensure greater transaction certainty and “Exit” pathways by:
Hosting exclusive online events, investment conferences, road shows and “Shark Tanks”
Trending & Activity Reports
Benchmarking the achievement of milestones and inflection points (v.s. Peers)
Exploiting proprietary capital markets tools, such as Matching, Targeting and Geo-Location
HealthiosXchange believes that the cornerstone of the global healthcare capital markets is the “Lead” institutional investor: Venture Capital, Growth Equity and Private Equity firms. In this capacity, the “Lead” investor plays a critically important role.
By providing Lead investors with extensive resources in support of the needs of their portfolio, while reducing financing risk, enhancing investment returns and extending the relationship of Lead investors with their own Limited Partners, HealthiosXchange seeks to make a indelible contribution to the culture of innovation, growth and value creation around the world