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UBS Global Life Sciences Conference




                        September 24, 2008
Who is Quest Diagnostics?
•Leader in Providing Healthcare Insights and Solutions
• Comprehensive Diagnostic Testing
    • Routine ——» Esoteric
           Diagnose
       •
           Monitor
       •
           Predict
       •
           Prevent
       •
–Advanced Information Technology Solutions
    • Improve Care and Efficiency
–Facilitate Introduction of New Therapeutics
    • Clinical Trials Testing
–Innovative Diagnostic Products
    • Enable Care Closer to the Patient
–Risk Assessment Solutions to Life Insurance Industry

 Touching Patients ~150 Million Times Each Year
                                                        Patients | Growth | People


                                                                                     2
The Leader in Diagnostic Testing

      • U.S. Diagnostic Testing Market: ~ $50 B




                      $ in millions




                                                                   Patients | Growth | People
Source: Washington G-2 Reports and company information

                                                                                                3
Favorable Industry Trends

  Essential Healthcare Service

• Growing and Aging Population

• Scientific & Medical Innovations

• Personal Interest in Health

• Convergence of Information


  Influences >70% of Healthcare Decisions
                                            Patients | Growth | People


                                                                         4
Moving to Higher Growth,
                              Higher Margin Segments

     2000 Revenue                  2007 Pro Forma Revenue




Total Revenue: $3.4 Billion      Total Pro Forma Revenue: $7.0 Billion


                                                         Patients | Growth | People


                                                                                      5
Expanding Market Leadership
                                                              2008
                                                 2000
• Clinical Testing                           •            •
• Gene-based & Esoteric Testing              •            •
• Employer Services                          •            •
• Anatomic Pathology Testing                 •P           •
• Risk Assessment Services                   •-           •
• Healthcare Information Technology          •-           •
• Point of Care (Near Patient) Testing       •-           •
• Clinical Trials Testing                    •P           •P
• International Market                       •-           •P

    Overall Market Leader/Niche Leadership
  P Market Participant                                  Patients | Growth | People


                                                                                     6
Our Goals

•Undisputed World Leader in Diagnostic Testing,
 Information and Services

•Profitably Grow > Industry Rate

•Expand Operating Income to 20%

•Expand International Operations to ~10% of Revenues




                                              Patients | Growth | People


                                                                           7
Strategy to Drive Profitable Growth

Sustainable Competitive Advantage

Deliver Superior Patient Experience
Continuously Drive Six Sigma Quality
Lead in Medical Innovation/Information
Leverage Unparalleled Assets & Capabilities
Expand Diagnostic Scope
Expand Geographic Reach

                                              Patients | Growth | People


                                                                           8
Delivering Superior Patient Experience

Patient Gold Standards
Prompt, caring, courteous service


PSC Appointment Scheduling
Only laboratory with appointment scheduling at PSCs
Reduces patient wait time; improves convenience


Google Health Collaboration
Facilitate patient-physician communications
Secure electronic access to lab results
                                                      Patients | Growth | People


                                                                                   9
Leading Medical Innovator

Multiple Channels to Access New Technology
   Internal Development – Nichols Institute
   Joint Development Relationships
   Licensing/Distribution Relationships
Focused on Addressing Areas of Significant Patient Need
   Cancer, Cardiovascular Conditions, Infectious Disease
   Less invasive; less painful; more convenient for patients
Leading Experts for Medical Consultation
   900 MDs & PhDs
Culture of Collaborative Innovation
   Academic relationships
   Investment in innovative firms and technologies
   Partnerships with pharmaceutical companies
                                                        Patients | Growth | People


                                                                                     10
Continual Stream of
                                    Diagnostic Testing Advances

Cancer                                Transplantation/Coagulation
   – LeumetaTM                           – HLA FDA-registered lab
   – HE-4                                – Coag consultations
   – H/I Breast Recurrence            New Technologies/New Applications
   – Cancer of Unknown Primary
                                         – XSenseTM (Fragile X)
Cardiovascular Disease                   – ClarisureTM (CGH Microarray)
   – Ion Mobility (Lipid Profile)        – LC/MS for Amino Acids
Infectious Disease                       – LC-MS/MS
   – HepaScoreTM                      Personalized Medicine
   – Chikungunya

                                                          Patients | Growth | People


                                                                                       11
Enabling Personalized and
                                      Targeted Medicine
  Enables More Appropriate Drug Therapy
     Rituxan®         Rituxan® Sensitivity (CD20)
     Herceptin®       Her2
     Campath®         Campath Sensitivity (CD2)
     Irinotecan       UGT1A1
     Warfarin         CYP450 2C9
     Carbamazephine   HLA - screens out certain Asian patients
     Abacavir         HLA - predisposition to hypersensitivity
     Aspirin          Monitor personal resistance levels
  Improves Disease Management
     Leumeta™         CellSearch
     Hepascore™

Improving Patient Care …..Reducing Medical Costs
                                                      Patients | Growth | People


                                                                                   12
Unparalleled Assets and Capabilities




                         Patients | Growth | People


                                                      13
Unique Brands and Services for
                                       Each Customer Type




Physicians                                 Hospital
                     Physician                                      Life Insurers
Hospitals            Hospital              Physician
Employers
International




                                                            Physicians
Point of care for:      Hospital Lab       Pharmaceutical
Hospitals                                                   Hospitals
                        Hospital Bedside    Companies
Physicians
Blood Banks                                                 Other provider groups
                                                                 Patients | Growth | People


                                                                                              14
Expanding Diagnostic Scope
                                   Near Patient Testing

Opportunity to Improve Patient Care

 Attractive benefits for hospitals,
 physician offices and
 international markets
 Enables more timely and
 effective decisions
 Expanding product menu
 Platform technology
 Results integrated into Care360

Reducing Medical Costs
                                               Patients | Growth | People


                                                                            15
Expanding Geographic Reach

Broadening Our Geographical Coverage

  Clear leadership in U.S….with room to grow

  Leverage existing labs in Puerto Rico, Mexico, and UK

  Increase foreign testing sent to Nichols Institute

  Exploit point of care distribution network in 130 countries

  Entering India – serving multiple markets

Increasing Market Opportunity
                                                   Patients | Growth | People


                                                                                16
India. . . An Untapped Opportunity

1 Billion People and Emerging Economic Power
  300 million people in middle class
  Expanding consumerism
Increased Incidence of Chronic Disease
  Diabetes: 17% (among the highest in the world)
  Hypertension: 51% of adults
  Hyperlipidemia
  Cancer: ~1 million new cases each year
  Infectious diseases: 1000 deaths/day from Tuberculosis
Expanding interest in early detection, prevention and treatment
Highly fragmented diagnostic testing market
                                                     Patients | Growth | People


                                                                                  17
Reducing Costs by $500 Million

Leverage Lean Six Sigma to Improve Efficiency

 Streamline Lab Operations

 Optimize Logistics Routes
 and PSC Resources

 Improve Billing and Call
 Center Operations

 Leverage Purchasing
 Capabilities

Maintain Service Levels & Stimulate Growth
                                                Patients | Growth | People


                                                                             18
2008 Q2 YTD Results

Returning to Earnings Growth

                            $3.6 B, ↑ 14.4%
Revenues

                            16.2%, ↑ 1.3%
Operating Income

                                     ↑~21%
EPS                         $1.55,

Cash from Operations        $371 million


Investing to Drive Superior Growth
                                              Patients | Growth | People


                                                                           19
2008 / 2009 Focus

  Margin Expansion and Earnings Growth

• Drive Top-Line Growth

• Integrate AmeriPath

• Reduce Costs by $500 Million

• Expand International and Products Businesses



  Excellence in Execution
                                                 Patients | Growth | People


                                                                              20
Building on Strength

Leader in a vital and growing industry

Strong cash generator, with a strong balance sheet

Uniquely positioned with unparalleled assets & capabilities

History of disciplined growth and successful acquisitions

Proven management team



Focused on Execution
                                                Patients | Growth | People


                                                                             21
Patients | Growth | People


                             22

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UBS Global Life Sciences Conference Quest Diagnostics Overview

  • 1. UBS Global Life Sciences Conference September 24, 2008
  • 2. Who is Quest Diagnostics? •Leader in Providing Healthcare Insights and Solutions • Comprehensive Diagnostic Testing • Routine ——» Esoteric Diagnose • Monitor • Predict • Prevent • –Advanced Information Technology Solutions • Improve Care and Efficiency –Facilitate Introduction of New Therapeutics • Clinical Trials Testing –Innovative Diagnostic Products • Enable Care Closer to the Patient –Risk Assessment Solutions to Life Insurance Industry Touching Patients ~150 Million Times Each Year Patients | Growth | People 2
  • 3. The Leader in Diagnostic Testing • U.S. Diagnostic Testing Market: ~ $50 B $ in millions Patients | Growth | People Source: Washington G-2 Reports and company information 3
  • 4. Favorable Industry Trends Essential Healthcare Service • Growing and Aging Population • Scientific & Medical Innovations • Personal Interest in Health • Convergence of Information Influences >70% of Healthcare Decisions Patients | Growth | People 4
  • 5. Moving to Higher Growth, Higher Margin Segments 2000 Revenue 2007 Pro Forma Revenue Total Revenue: $3.4 Billion Total Pro Forma Revenue: $7.0 Billion Patients | Growth | People 5
  • 6. Expanding Market Leadership 2008 2000 • Clinical Testing • • • Gene-based & Esoteric Testing • • • Employer Services • • • Anatomic Pathology Testing •P • • Risk Assessment Services •- • • Healthcare Information Technology •- • • Point of Care (Near Patient) Testing •- • • Clinical Trials Testing •P •P • International Market •- •P Overall Market Leader/Niche Leadership P Market Participant Patients | Growth | People 6
  • 7. Our Goals •Undisputed World Leader in Diagnostic Testing, Information and Services •Profitably Grow > Industry Rate •Expand Operating Income to 20% •Expand International Operations to ~10% of Revenues Patients | Growth | People 7
  • 8. Strategy to Drive Profitable Growth Sustainable Competitive Advantage Deliver Superior Patient Experience Continuously Drive Six Sigma Quality Lead in Medical Innovation/Information Leverage Unparalleled Assets & Capabilities Expand Diagnostic Scope Expand Geographic Reach Patients | Growth | People 8
  • 9. Delivering Superior Patient Experience Patient Gold Standards Prompt, caring, courteous service PSC Appointment Scheduling Only laboratory with appointment scheduling at PSCs Reduces patient wait time; improves convenience Google Health Collaboration Facilitate patient-physician communications Secure electronic access to lab results Patients | Growth | People 9
  • 10. Leading Medical Innovator Multiple Channels to Access New Technology Internal Development – Nichols Institute Joint Development Relationships Licensing/Distribution Relationships Focused on Addressing Areas of Significant Patient Need Cancer, Cardiovascular Conditions, Infectious Disease Less invasive; less painful; more convenient for patients Leading Experts for Medical Consultation 900 MDs & PhDs Culture of Collaborative Innovation Academic relationships Investment in innovative firms and technologies Partnerships with pharmaceutical companies Patients | Growth | People 10
  • 11. Continual Stream of Diagnostic Testing Advances Cancer Transplantation/Coagulation – LeumetaTM – HLA FDA-registered lab – HE-4 – Coag consultations – H/I Breast Recurrence New Technologies/New Applications – Cancer of Unknown Primary – XSenseTM (Fragile X) Cardiovascular Disease – ClarisureTM (CGH Microarray) – Ion Mobility (Lipid Profile) – LC/MS for Amino Acids Infectious Disease – LC-MS/MS – HepaScoreTM Personalized Medicine – Chikungunya Patients | Growth | People 11
  • 12. Enabling Personalized and Targeted Medicine Enables More Appropriate Drug Therapy Rituxan® Rituxan® Sensitivity (CD20) Herceptin® Her2 Campath® Campath Sensitivity (CD2) Irinotecan UGT1A1 Warfarin CYP450 2C9 Carbamazephine HLA - screens out certain Asian patients Abacavir HLA - predisposition to hypersensitivity Aspirin Monitor personal resistance levels Improves Disease Management Leumeta™ CellSearch Hepascore™ Improving Patient Care …..Reducing Medical Costs Patients | Growth | People 12
  • 13. Unparalleled Assets and Capabilities Patients | Growth | People 13
  • 14. Unique Brands and Services for Each Customer Type Physicians Hospital Physician Life Insurers Hospitals Hospital Physician Employers International Physicians Point of care for: Hospital Lab Pharmaceutical Hospitals Hospitals Hospital Bedside Companies Physicians Blood Banks Other provider groups Patients | Growth | People 14
  • 15. Expanding Diagnostic Scope Near Patient Testing Opportunity to Improve Patient Care Attractive benefits for hospitals, physician offices and international markets Enables more timely and effective decisions Expanding product menu Platform technology Results integrated into Care360 Reducing Medical Costs Patients | Growth | People 15
  • 16. Expanding Geographic Reach Broadening Our Geographical Coverage Clear leadership in U.S….with room to grow Leverage existing labs in Puerto Rico, Mexico, and UK Increase foreign testing sent to Nichols Institute Exploit point of care distribution network in 130 countries Entering India – serving multiple markets Increasing Market Opportunity Patients | Growth | People 16
  • 17. India. . . An Untapped Opportunity 1 Billion People and Emerging Economic Power 300 million people in middle class Expanding consumerism Increased Incidence of Chronic Disease Diabetes: 17% (among the highest in the world) Hypertension: 51% of adults Hyperlipidemia Cancer: ~1 million new cases each year Infectious diseases: 1000 deaths/day from Tuberculosis Expanding interest in early detection, prevention and treatment Highly fragmented diagnostic testing market Patients | Growth | People 17
  • 18. Reducing Costs by $500 Million Leverage Lean Six Sigma to Improve Efficiency Streamline Lab Operations Optimize Logistics Routes and PSC Resources Improve Billing and Call Center Operations Leverage Purchasing Capabilities Maintain Service Levels & Stimulate Growth Patients | Growth | People 18
  • 19. 2008 Q2 YTD Results Returning to Earnings Growth $3.6 B, ↑ 14.4% Revenues 16.2%, ↑ 1.3% Operating Income ↑~21% EPS $1.55, Cash from Operations $371 million Investing to Drive Superior Growth Patients | Growth | People 19
  • 20. 2008 / 2009 Focus Margin Expansion and Earnings Growth • Drive Top-Line Growth • Integrate AmeriPath • Reduce Costs by $500 Million • Expand International and Products Businesses Excellence in Execution Patients | Growth | People 20
  • 21. Building on Strength Leader in a vital and growing industry Strong cash generator, with a strong balance sheet Uniquely positioned with unparalleled assets & capabilities History of disciplined growth and successful acquisitions Proven management team Focused on Execution Patients | Growth | People 21
  • 22. Patients | Growth | People 22