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NEUMOLOGIA :UPDATE
(COSECHA DEL 14-15)
Josep Morera
Isabel Badorrey
Carlos Martínez-Rivera
Núria Angrill
Rosa Luz
Laura Sebastián
BARCELONA 9 MAIG 2015
2
3
4
5
CONTENIDO
- Asma Bronquial
- EPOC
- Bronquiectasias
- Cáncer de Pulmón
- Tabaquismo
- Tos
- Neumonía
- Tuberculosis
- SLEEP –APNEA
- Fibrosis Pulmonar Idiopática
- Nuevas enfermedades
- Conclusiones
6
ASMA BRONQUIAL
7
ASMA BRONQUIAL
N Engl J Med 2014;371:1198-1207.
8
ASMA BRONQUIAL
9
ASMA BRONQUIAL
What Is the Role of Tiotropium in
Asthma?:
A Systematic Review With Meta-analysis
Gustavo J. Rodrigo, MD; José A. Castro-Rodríguez, MD, PhD
Chest. 2015;147(2):388-396
10
EPOC
EPOC: Evaluación de la función pulmonar
durante 24 horas
wmFEV1 de 24-h de Relvar®
92/22 mcg (n=33) vs. placebo (n=51) en los días 28–29 1
Adaptado de Boscia JA, et al. Clin Ther 2012;34:1655–66e5
EPOC
12
Dual bronchodilation with QVA149 reduces patient-
reported dyspnoea in COPD: the BLAZE study.
Mahler DA. Eur Respir J. 2014 Jun;43(6):1599-609: 2013
EPOC
13
EPOC
14
EPOC
15
EPOC
16
BRONQUIECTASIAS
Thorax. 2015 May;70(5):399-400
February 1, 2015 vol. 45 no. 2 310-313
17
BRONQUIECTASIAS
18
Thorax. 2015 Apr;70(4):326-32
CANCER DE PULMÓN
19
CANCER DE PULMÓN
20
CANCER DE PULMÓN
N Engl J Med. 2015 Apr 19. [Epub ahead of print]
21
TABAQUISMO
COPD: Undefeated!
Mohsen Sadatsafavi, MD, PhD; Don D. Sin, MD, FCCP
Chest. 2015;147(4):868-869.
22
T
O
S
www.drjosepmorera.comwww.drjosepmorera.com
23
TOS
The Spectrum of Lung Disease due to
Chronic Occult Aspiration
John J. Cardasis1, Heber MacMahon2, and Aliya N. Husain3
Annals ATS Volume 11 Number 6|July 2014
24
TOS
The Spectrum of Lung Disease due to
Chronic Occult Aspiration
John J. Cardasis1, Heber MacMahon2, and Aliya N. Husain3
Annals ATS Volume 11 Number 6|July 2014
25
Effect of Corticosteroids on Treatment Failure
Among Hospitalized Patients With Severe
Community-Acquired Pneumonia and High
Inflammatory ResponseA Randomized Clinical
Trial
Antoni Torres, MD et al. JAMA. 2015;313(7):677-686.
NEUMONIA
Conclusions and Relevance Among patients with severe
community-acquired pneumonia and high initial inflammatory
response, the acute use of methylprednisolone compared with
placebo decreased treatment failure. If replicated, these findings
would support the use of corticosteroids as adjunctive treatment in
this clinical population.
26
NEUMONIA
The lancet vol 385 April 18, 2015
27
NEUMONIA
N Engl J Med 2015;372:1114-1125
28
NEUMONIA
n engl j med 372; February 26, 2015
29
www.drjosepmorera.comwww.drjosepmorera.com
TUBERCULOSIS
However, the drug should be available in a very controlled manner in the
context of special access programs for the treatment of MDR tuberculosis,
linking funding to the generation of evidence or the achievement of clinical
results previously agreed.
In 2013, among the world reported cases of pulmo- nary tuberculosis, 450,000 were
MDR-TB or XDR-TB. Almost 60% of them were located at India, China and Russian
Federation. In Spain, in 2012, 6,046 cases of tu- berculosis were reported, with a 3.9-
4.3% proportion of MDR-TB; and approximately 6% of them could be XDR- TB, a
higher ratio than other occidental countries
30
www.drjosepmorera.comwww.drjosepmorera.com
TUBERCULOSIS
Eur Respir J 2015; 45: 317–321
31
www.drjosepmorera.comwww.drjosepmorera.com
TUBERCULOSIS
32
www.drjosepmorera.comwww.drjosepmorera.com
SLEEP-APNEA
33
www.drjosepmorera.comwww.drjosepmorera.com
SLEEP-APNEA
Is obstructive sleep apnea associated with the risk
of ischemic stroke in patients with atrial
fibrillation?Filip M. Szymanski , Anna E. Platek , Krzysztof J. Filipiak
April 1, 2015Volume 184, Pages 481–482
Impact of Obstructive Sleep Apnea on Cardiovascular
Events after Coronary Artery Bypass Surgery
Carlos Henrique G. Uchôa, PT; Naury de Jesus Danzi-Soares, RN, PhD; Flávia S. Nunes,
MD, PhD; Altay A. L. de Souza; Flávia B. Nerbass, PT; Rodrigo P. Pedrosa, MD, PhD; Luiz
Antonio M. César, MD, PhD; Geraldo Lorenzi-Filho, MD, PhD; Luciano F. Drager, MD,
PhD Chest. 2015.
34
www.drjosepmorera.comwww.drjosepmorera.com
SLEEP-APNEA
January 2015, Vol 147, No. 1
35
FIBROSIS PULMONAR IDIOPÁTICA
36
NUEVAS ENFERMEDADES
Thorax 2014;69:692-693
37
CONCLUSIONES
38
MUCHAS GRACIAS !!

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