This document contains a summary of topics in pulmonology, including asthma, COPD, bronchiectasis, lung cancer, smoking, cough, pneumonia, tuberculosis, sleep apnea, idiopathic pulmonary fibrosis, and new diseases. It discusses recent studies on these topics published between 2014 and 2015. The document is presented as part of an update in pulmonology given on May 9, 2015 in Barcelona.
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COPD and Asthma Updates
1. 1
NEUMOLOGIA :UPDATE
(COSECHA DEL 14-15)
Josep Morera
Isabel Badorrey
Carlos Martínez-Rivera
Núria Angrill
Rosa Luz
Laura Sebastián
BARCELONA 9 MAIG 2015
9. 9
ASMA BRONQUIAL
What Is the Role of Tiotropium in
Asthma?:
A Systematic Review With Meta-analysis
Gustavo J. Rodrigo, MD; José A. Castro-Rodríguez, MD, PhD
Chest. 2015;147(2):388-396
11. EPOC: Evaluación de la función pulmonar
durante 24 horas
wmFEV1 de 24-h de Relvar®
92/22 mcg (n=33) vs. placebo (n=51) en los días 28–29 1
Adaptado de Boscia JA, et al. Clin Ther 2012;34:1655–66e5
EPOC
12. 12
Dual bronchodilation with QVA149 reduces patient-
reported dyspnoea in COPD: the BLAZE study.
Mahler DA. Eur Respir J. 2014 Jun;43(6):1599-609: 2013
EPOC
23. 23
TOS
The Spectrum of Lung Disease due to
Chronic Occult Aspiration
John J. Cardasis1, Heber MacMahon2, and Aliya N. Husain3
Annals ATS Volume 11 Number 6|July 2014
24. 24
TOS
The Spectrum of Lung Disease due to
Chronic Occult Aspiration
John J. Cardasis1, Heber MacMahon2, and Aliya N. Husain3
Annals ATS Volume 11 Number 6|July 2014
25. 25
Effect of Corticosteroids on Treatment Failure
Among Hospitalized Patients With Severe
Community-Acquired Pneumonia and High
Inflammatory ResponseA Randomized Clinical
Trial
Antoni Torres, MD et al. JAMA. 2015;313(7):677-686.
NEUMONIA
Conclusions and Relevance Among patients with severe
community-acquired pneumonia and high initial inflammatory
response, the acute use of methylprednisolone compared with
placebo decreased treatment failure. If replicated, these findings
would support the use of corticosteroids as adjunctive treatment in
this clinical population.
29. 29
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TUBERCULOSIS
However, the drug should be available in a very controlled manner in the
context of special access programs for the treatment of MDR tuberculosis,
linking funding to the generation of evidence or the achievement of clinical
results previously agreed.
In 2013, among the world reported cases of pulmo- nary tuberculosis, 450,000 were
MDR-TB or XDR-TB. Almost 60% of them were located at India, China and Russian
Federation. In Spain, in 2012, 6,046 cases of tu- berculosis were reported, with a 3.9-
4.3% proportion of MDR-TB; and approximately 6% of them could be XDR- TB, a
higher ratio than other occidental countries
33. 33
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SLEEP-APNEA
Is obstructive sleep apnea associated with the risk
of ischemic stroke in patients with atrial
fibrillation?Filip M. Szymanski , Anna E. Platek , Krzysztof J. Filipiak
April 1, 2015Volume 184, Pages 481–482
Impact of Obstructive Sleep Apnea on Cardiovascular
Events after Coronary Artery Bypass Surgery
Carlos Henrique G. Uchôa, PT; Naury de Jesus Danzi-Soares, RN, PhD; Flávia S. Nunes,
MD, PhD; Altay A. L. de Souza; Flávia B. Nerbass, PT; Rodrigo P. Pedrosa, MD, PhD; Luiz
Antonio M. César, MD, PhD; Geraldo Lorenzi-Filho, MD, PhD; Luciano F. Drager, MD,
PhD Chest. 2015.