This work explores how people’s beliefs about suffering shape the way they respond to difficult experiences. Two mindsets appear: a debilitative mindset, which sees suffering as harmful and limiting, and a facilitative mindset, which views suffering as something that can bring meaning, growth, and connection. These mindsets influence well-being, reactions to hardship, and even how strongly suffering is perceived. We identified five key dimensions—meaning in life, personal growth, solidarity, transformation, and the net effect of suffering—and developed a scale to measure them. Our findings highlight the importance of understanding how individuals interpret suffering and how these interpretations can support resilience and positive change.